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PDB: 69 件

6O7I
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Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6O7H
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BU of 6o7h by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6PPR
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BU of 6ppr by Molmil
Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and DNA
分子名称: ATP-dependent DNA helicase (UvrD/REP), DNA (70-MER), IRON/SULFUR CLUSTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-08
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PPJ
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BU of 6ppj by Molmil
Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP
分子名称: ATP-dependent DNA helicase (UvrD/REP), IRON/SULFUR CLUSTER, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-07
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
6O7E
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BU of 6o7e by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system
分子名称: Csm1, Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6PPU
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BU of 6ppu by Molmil
Cryo-EM structure of AdnAB-AMPPNP-DNA complex
分子名称: ATP-dependent DNA helicase (UvrD/REP), DNA (29-MER), IRON/SULFUR CLUSTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-08
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MUR
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BU of 6mur by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
分子名称: RNA (27-MER), RNA (5'-R(P*GP*CP*AP*AP*AP*CP*CP*GP*CP*CP*UP*CP*UP*GP*CP*CP*CP*GP*C)-3'), Uncharacterized protein, ...
著者Jia, N, Wang, C, Eng, E.T, Patel, D.J.
登録日2018-10-23
公開日2018-12-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUS
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Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
分子名称: RNA (25-MER), RNA (33-MER), Uncharacterized protein Csm1, ...
著者Jia, N, Wang, C, Eng, E.T.
登録日2018-10-23
公開日2018-12-12
最終更新日2019-01-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUA
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Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex
分子名称: Uncharacterized protein Csm1, Uncharacterized protein Csm4
著者Jia, N, Patel, D.J.
登録日2018-10-22
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUT
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BU of 6mut by Molmil
Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system
分子名称: RNA (5'-R(*GP*UP*GP*GP*AP*AP*AP*GP*GP*CP*GP*GP*GP*CP*AP*GP*AP*GP*GP*C)-3'), RNA (5'-R(P*CP*CP*UP*CP*UP*GP*CP*CP*CP*GP*CP*CP*UP*UP*UP*CP*CP*AP*C)-3'), Uncharacterized protein Csm1, ...
著者Jia, N, Wang, C, Eng, E.T, Patel, D.J.
登録日2018-10-23
公開日2018-12-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUU
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Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system
分子名称: RNA (25-MER), Uncharacterized protein Csm1, Uncharacterized protein Csm2, ...
著者Jia, N, Wang, C, Eng, E.T, Patel, D.J.
登録日2018-10-23
公開日2018-12-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
5Y6K
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BU of 5y6k by Molmil
Human serum trnasferrin bound to a fluorescent probe
分子名称: (2S)-6-[2-(7-azido-4-methyl-2-oxidanylidene-chromen-3-yl)ethanoylamino]-2-[bis(2-hydroxy-2-oxoethyl)amino]hexanoic acid, FE (III) ION, MALONATE ION, ...
著者Jiang, N, Cheng, T, Wang, M, Chan, G.C.F, Jin, L, Li, H, Sun, H.
登録日2017-08-12
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Tracking iron-associated proteomes in pathogens by a fluorescence approach.
Metallomics, 10, 2018
4QLA
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BU of 4qla by Molmil
Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori
分子名称: Juvenile hormone epoxide hydrolase, PENTAETHYLENE GLYCOL
著者Zhou, K, Jia, N, Hu, C, Jiang, Y.L, Yang, J.P, Chen, Y, Li, S, Zhou, C.Z.
登録日2014-06-11
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori.
Proteins, 82, 2014
8IFM
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BU of 8ifm by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2
分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
著者Zhang, J.T, Jia, N.
登録日2023-02-18
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
7XF0
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BU of 7xf0 by Molmil
Crystal strucutre of CasDinG in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CasDinG
著者Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
登録日2022-03-31
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XF1
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BU of 7xf1 by Molmil
Crystal strucutre of apoCasDinG in complex with ssDNA
分子名称: CasDinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')
著者Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
登録日2022-03-31
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XEX
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BU of 7xex by Molmil
Crystal strucutre of apoCasDinG
分子名称: CasDinG
著者Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
登録日2022-03-31
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG1
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BU of 7xg1 by Molmil
CryoEM structure of type IV-A Csf-crRNA binary complex
分子名称: Csf1, Csf2, Csf3, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-04-02
公開日2023-08-02
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
Mol.Cell, 83, 2023
7XG3
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BU of 7xg3 by Molmil
CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex
分子名称: Csf1, Csf2, Csf3, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-04-02
公開日2023-08-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XFZ
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BU of 7xfz by Molmil
CryoEM structure of type IV-A Csf-crRNAsp14-dsDNA ternary complex
分子名称: Csf1, Csf2, Csf3, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-04-02
公開日2023-08-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG0
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BU of 7xg0 by Molmil
CryoEM structure of type IV-A Csf-crRNA-dsDNA ternary complex
分子名称: Csf1, Csf2, Csf3, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-04-02
公開日2023-08-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG4
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CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex in a second state
分子名称: Csf1, Csf2, Csf3, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-04-02
公開日2023-08-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG2
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BU of 7xg2 by Molmil
CryoEM structure of type IV-A NTS-nicked dsDNA bound Csf-crRNA ternary complex
分子名称: Csf1, Csf2, Csf3, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-04-02
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
8K34
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BU of 8k34 by Molmil
Cryo-EM structure of SPARTA gRNA binary complex
分子名称: MAGNESIUM ION, Piwi domain-containing protein, RNA (5'-R(P*AP*AP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ...
著者Zhang, J.T, Jia, N.
登録日2023-07-14
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
8IFL
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BU of 8ifl by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1
分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
著者Zhang, J.T, Jia, N.
登録日2023-02-18
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024

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