8SZE
| Crystal structure of Yersinia pestis dihydrofolate reductase in complex with Trimethoprim | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Dihydrofolate reductase, ... | Authors: | Shaw, G.X, Cherry, S, Tropea, J.E, Waugh, D.S, Ji, X. | Deposit date: | 2023-05-29 | Release date: | 2023-06-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Yersinia pestis dihydrofolate reductase in complex with Trimethoprim To be published
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1L4Y
| CRYSTAL STRUCTURE OF SHIKIMATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MGADP AT 2.0 ANGSTROM RESOLUTION | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Gu, Y, Reshetnikova, L, Li, Y, Wu, Y, Yan, H, Singh, S, Ji, X. | Deposit date: | 2002-03-06 | Release date: | 2002-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis. J.Mol.Biol., 319, 2002
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5Z0V
| Structural insight into the Zika virus capsid encapsulating the viral genome | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | Deposit date: | 2017-12-21 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.913 Å) | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
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5Z0R
| Structural insight into the Zika virus capsid encapsulating the viral genome | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | Deposit date: | 2017-12-20 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
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3FTD
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3FTF
| Crystal structure of A. aeolicus KsgA in complex with RNA and SAH | Descriptor: | 5'-R(P*AP*AP*CP*CP*GP*UP*AP*GP*GP*GP*GP*AP*AP*CP*CP*UP*GP*CP*GP*GP*UP*U)-3', Dimethyladenosine transferase, POTASSIUM ION, ... | Authors: | Tu, C, Ji, X. | Deposit date: | 2009-01-12 | Release date: | 2009-03-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase. Structure, 17, 2009
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3FTC
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3FTE
| Crystal structure of A. aeolicus KsgA in complex with RNA | Descriptor: | 5'-R(P*AP*AP*CP*CP*GP*UP*AP*GP*GP*GP*GP*AP*AP*CP*CP*UP*GP*CP*GP*GP*UP*U)-3', Dimethyladenosine transferase | Authors: | Tu, C, Ji, X. | Deposit date: | 2009-01-12 | Release date: | 2009-03-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase. Structure, 17, 2009
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2LXH
| NMR structure of the RING domain in ubiquitin ligase gp78 | Descriptor: | E3 ubiquitin-protein ligase AMFR, ZINC ION | Authors: | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | Deposit date: | 2012-08-27 | Release date: | 2013-08-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
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2LXP
| NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION | Authors: | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | Deposit date: | 2012-08-30 | Release date: | 2013-08-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
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6PBZ
| Crystal structure of Escherichia coli GppA | Descriptor: | CHLORIDE ION, Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase | Authors: | Song, H, Shaw, G.X, Wang, C, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.475 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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8H01
| SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in class 2 conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-09-27 | Release date: | 2023-04-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants. Commun Biol, 6, 2023
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8H00
| SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in the class 1 conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-09-27 | Release date: | 2023-04-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants. Commun Biol, 6, 2023
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6PC3
| Crystal structure of Helicobacter pylori PPX/GppA in complex with GSP | Descriptor: | 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CHLORIDE ION, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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6PC2
| Crystal structure of Helicobacter pylori PPX/GppA in complex with GNP | Descriptor: | Guanosine pentaphosphate phosphohydrolase, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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8ITU
| SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 IgG. | Descriptor: | 1H1 heavy chain, 1H1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2023-03-23 | Release date: | 2023-04-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants. Commun Biol, 6, 2023
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5GJB
| Zika virus NS3 helicase in complex with ssRNA | Descriptor: | NS3 helicase, RNA (5'-R(*AP*GP*AP*UP*CP*AP*A)-3') | Authors: | Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H. | Deposit date: | 2016-06-28 | Release date: | 2016-07-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Structural basis of Zika virus helicase in recognizing its substrates Protein Cell, 7, 2016
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5GJC
| Zika virus NS3 helicase in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, NS3 helicase | Authors: | Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H. | Deposit date: | 2016-06-28 | Release date: | 2016-07-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structural basis of Zika virus helicase in recognizing its substrates Protein Cell, 7, 2016
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1RHH
| Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution | Descriptor: | Fab X5, heavy chain, light chain | Authors: | Darbha, R, Phogat, S, Labrijn, A.F, Shu, Y, Gu, Y, Andrykovitch, M, Zhang, M.Y, Pantophlet, R, Martin, L, Vita, C, Burton, D.R, Dimitrov, D.S, Ji, X. | Deposit date: | 2003-11-14 | Release date: | 2004-02-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope Biochemistry, 43, 2004
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1TDI
| Crystal Structure of hGSTA3-3 in Complex with Glutathione | Descriptor: | GLUTATHIONE, Glutathione S-transferase A3-3 | Authors: | Gu, Y, Guo, J, Pal, A, Pan, S.S, Zimniak, P, Singh, S.V, Ji, X. | Deposit date: | 2004-05-22 | Release date: | 2005-01-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity. Biochemistry, 43, 2004
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1I4S
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3HD2
| Crystal structure of E. coli HPPK(Q50A) in complex with MgAMPCPP and pterin | Descriptor: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, CHLORIDE ION, ... | Authors: | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | Deposit date: | 2009-05-06 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published
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3HD1
| Crystal structure of E. coli HPPK(N10A) in complex with MgAMPCPP | Descriptor: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, CHLORIDE ION, ... | Authors: | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | Deposit date: | 2009-05-06 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published
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3HSZ
| Crystal structure of E. coli HPPK(F123A) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | Deposit date: | 2009-06-11 | Release date: | 2010-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
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3HT0
| Crystal structure of E. coli HPPK(F123A) in complex with MgAMPCPP | Descriptor: | CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, HPPK, ... | Authors: | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | Deposit date: | 2009-06-11 | Release date: | 2010-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
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