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PDB: 5 件
6ARK
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BU of 6ark by Molmil
Crystal Structure of compound 10 covalently bound to K-Ras G12C
分子名称: (3R)-N-(6-bromonaphthalen-2-yl)-3-hydroxy-1-propanoyl-L-prolinamide, GLYCEROL, GTPase KRas, ...
著者Nnadi, C.I, Jenkins, M.L, Gentile, D.R, Bateman, L.A, Zaidman, D, Balius, T.E, Nomura, D.K, Burke, J.E, Shokat, K.M, London, N.
登録日2017-08-22
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Novel K-Ras G12C Switch-II Covalent Binders Destabilize Ras and Accelerate Nucleotide Exchange.
J Chem Inf Model, 58, 2018
6DJL
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BU of 6djl by Molmil
Crystal structure of the Rab11 GEF SH3BP5 bound to nucleotide free Rab11A
分子名称: Ras-related protein Rab-11A, SH3 domain-binding protein 5
著者Burke, J.E, Jenkins, M.L, Boulanger, M.J.
登録日2018-05-25
公開日2018-09-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.10001159 Å)
主引用文献Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5.
Nat Commun, 9, 2018
5VBE
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BU of 5vbe by Molmil
Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GDP
分子名称: 1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gentile, D.R, Jenkins, M.L, Moss, S.M, Burke, J.E, Shokat, K.M.
登録日2017-03-29
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Cell Chem Biol, 24, 2017
5VBM
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BU of 5vbm by Molmil
Crystal Structure of Small Molecule Disulfide 2C07 Bound to K-Ras Cys Light M72C GDP
分子名称: 1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gentile, D.R, Jenkins, M.L, Moss, S.M, Burke, J.E, Shokat, K.M.
登録日2017-03-29
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Cell Chem Biol, 24, 2017
5VBZ
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BU of 5vbz by Molmil
Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GppNHp
分子名称: 1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide, GTPase HRas, MAGNESIUM ION, ...
著者Gentile, D.R, Jenkins, M.L, Moss, S.M, Burke, J.E, Shokat, K.M.
登録日2017-03-30
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Cell Chem Biol, 24, 2017

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件を2024-10-02に公開中

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