4L5Y
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![BU of 4l5y by Molmil](/molmil-images/mine/4l5y) | Methylthioadenosine phosphorylase from Schistosoma mansoni in APO form | 分子名称: | PHOSPHATE ION, S-methyl-5'-thioadenosine phosphorylase | 著者 | Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2013-06-11 | 公開日 | 2014-06-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.0957 Å) | 主引用文献 | Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
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7N5V
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![BU of 7n5v by Molmil](/molmil-images/mine/7n5v) | ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 20) | 分子名称: | DNA Strand I, DNA Strand II, ZINC ION, ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2021-06-06 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia. J.Biol.Chem., 299, 2023
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5CJ3
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![BU of 5cj3 by Molmil](/molmil-images/mine/5cj3) | Crystal structure of the zorbamycin binding protein (ZbmA) from Streptomyces flavoviridis with zorbamycin | 分子名称: | CHLORIDE ION, COPPER (II) ION, Zbm binding protein, ... | 著者 | Chang, C, Bigelow, L, Clancy, S, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Rudolf, J.D, Ma, M, Chang, C.-Y, Lohman, J.R, Yang, D, Shen, B, Enzyme Discovery for Natural Product Biosynthesis, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2015-07-13 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6499 Å) | 主引用文献 | Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892. Biochemistry, 54, 2015
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6UT2
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![BU of 6ut2 by Molmil](/molmil-images/mine/6ut2) | 3D structure of the leiomodin/tropomyosin binding interface | 分子名称: | Leiomodin-2, Tropomyosin alpha-1 chain chimeric peptide | 著者 | Tolkatchev, D, Smith, G.E, Helms, G.L, Cort, J.R, Kostyukova, A.S. | 登録日 | 2019-10-29 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Leiomodin creates a leaky cap at the pointed end of actin-thin filaments. Plos Biol., 18, 2020
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5C7J
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![BU of 5c7j by Molmil](/molmil-images/mine/5c7j) | CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | 分子名称: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | 著者 | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2015-06-24 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
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1DQU
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![BU of 1dqu by Molmil](/molmil-images/mine/1dqu) | CRYSTAL STRUCTURE OF THE ISOCITRATE LYASE FROM ASPERGILLUS NIDULANS | 分子名称: | ISOCITRATE LYASE | 著者 | Britton, K.L, Langridge, S.J, Baker, P.J, Weeradechapon, K, Sedelnikova, S.E, De Lucas, J.R, Rice, D.W, Turner, G. | 登録日 | 2000-01-05 | 公開日 | 2000-05-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The crystal structure and active site location of isocitrate lyase from the fungus Aspergillus nidulans. Structure Fold.Des., 8, 2000
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6UYB
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![BU of 6uyb by Molmil](/molmil-images/mine/6uyb) | Crystal structure of TEAD2 bound to Compound 1 | 分子名称: | (3R,4R)-1-{3-[(E)-2-(4-chlorophenyl)ethenyl]-4-methoxy-5-methylphenyl}-3,4-dihydroxypyrrolidin-2-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | 著者 | Noland, C.L, Holden, J.K, Crawford, J.J, Zbieg, J.R, Cunningham, C.N. | 登録日 | 2019-11-12 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.543 Å) | 主引用文献 | Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling. Cell Rep, 31, 2020
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5CEH
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![BU of 5ceh by Molmil](/molmil-images/mine/5ceh) | Structure of histone lysine demethylase KDM5A in complex with selective inhibitor | 分子名称: | 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, NICKEL (II) ION, ... | 著者 | Kiefer, J.R, Vinogradova, M. | 登録日 | 2015-07-06 | 公開日 | 2016-05-18 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nat.Chem.Biol., 12, 2016
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1DVC
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![BU of 1dvc by Molmil](/molmil-images/mine/1dvc) | SOLUTION NMR STRUCTURE OF HUMAN STEFIN A AT PH 5.5 AND 308K, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | STEFIN A | 著者 | Martin, J.R, Craven, C.J, Jerala, R, Kroon-Zitko, L, Zerovnik, E, Turk, V, Waltho, J.P. | 登録日 | 1996-02-26 | 公開日 | 1996-08-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The three-dimensional solution structure of human stefin A. J.Mol.Biol., 246, 1995
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6V62
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![BU of 6v62 by Molmil](/molmil-images/mine/6v62) | SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine | 分子名称: | 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ... | 著者 | Dai, S, Horton, J.R, Cheng, X. | 登録日 | 2019-12-04 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation. J.Biol.Chem., 295, 2020
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6UTE
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![BU of 6ute by Molmil](/molmil-images/mine/6ute) | Crystal structure of Z032 Fab in complex with WNV EDIII | 分子名称: | Envelope domain III, GLYCEROL, Z032 Fab heavy chain, ... | 著者 | Esswein, S.R, Gristick, H.B, Keeffe, J.R, Bjorkman, P.J. | 登録日 | 2019-10-29 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody. Proc.Natl.Acad.Sci.USA, 117, 2020
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7NJZ
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![BU of 7njz by Molmil](/molmil-images/mine/7njz) | X-ray crystallography study of RoAb13 which binds to PIYDIN, a part of the CCR5 N terminal domain | 分子名称: | Antibody RoAb13 Heavy Chain, Antibody RoAb13 Light Chain, Region from C-C chemokine receptor type 5 N-terminal domain | 著者 | Helliwell, J.R, Chayen, N, Saridakis, E, Govada, L. | 登録日 | 2021-02-17 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5. Iucrj, 8, 2021
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6UYA
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![BU of 6uya by Molmil](/molmil-images/mine/6uya) | Crystal structure of Compound 19 bound to IRAK4 | 分子名称: | Interleukin-1 receptor-associated kinase 4, N-{2-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-6-(morpholin-4-yl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide, SULFATE ION | 著者 | Kiefer, J.R, Bryan, M.C, Lupardus, P.J, Zarrin, A.A, Rajapaksa, N.S, Gobbi, A, Drobnick, J, Kolesnikov, A, Liang, J, Do, S. | 登録日 | 2019-11-12 | 公開日 | 2019-11-20 | 最終更新日 | 2020-04-01 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity. Acs Med.Chem.Lett., 11, 2020
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5CEI
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![BU of 5cei by Molmil](/molmil-images/mine/5cei) | Crystal structure of CDK8:Cyclin C complex with compound 22 | 分子名称: | 1,2-ETHANEDIOL, 4-(4-iodophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide, Cyclin-C, ... | 著者 | Kiefer, J.R, Schneider, E.V, Maskos, K, Koehler, M.F.T. | 登録日 | 2015-07-06 | 公開日 | 2016-02-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells. Acs Med.Chem.Lett., 7, 2016
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7OI1
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5CHH
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![BU of 5chh by Molmil](/molmil-images/mine/5chh) | Crystal structure of transcriptional regulator CdpR from Pseudomonas aeruginosa | 分子名称: | AraC family transcriptional regulator | 著者 | Zhao, J.R, Yu, X, Zhu, M, Kang, H.P, Kong, W.N, Ma, J.B, Deng, X, Gan, J.H, Liang, H.H. | 登録日 | 2015-07-10 | 公開日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa Plos Biol., 14, 2016
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5DVK
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![BU of 5dvk by Molmil](/molmil-images/mine/5dvk) | Fc Design 7.7 B chain homodimer T366V/K409I | 分子名称: | Ig gamma-1 chain C region | 著者 | Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. | 登録日 | 2015-09-21 | 公開日 | 2016-03-30 | 最終更新日 | 2016-04-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
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5DW5
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4FNJ
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5E0E
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![BU of 5e0e by Molmil](/molmil-images/mine/5e0e) | |
4L5C
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![BU of 4l5c by Molmil](/molmil-images/mine/4l5c) | Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine in space group P212121 | 分子名称: | ADENINE, GLYCEROL, S-methyl-5'-thioadenosine phosphorylase | 著者 | Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2013-06-10 | 公開日 | 2014-06-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.075 Å) | 主引用文献 | Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
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4FHT
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![BU of 4fht by Molmil](/molmil-images/mine/4fht) | Crystal Structure of the PcaV transcriptional regulator from Streptomyces coelicolor in complex with its natural ligand | 分子名称: | 3,4-DIHYDROXYBENZOIC ACID, ACETATE ION, PcaV transcriptional regulator | 著者 | Brown, B.L, Davis, J.R, Sello, J.K, Page, R. | 登録日 | 2012-06-06 | 公開日 | 2013-04-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Study of PcaV from Streptomyces coelicolor yields new insights into ligand-responsive MarR family transcription factors. Nucleic Acids Res., 41, 2013
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5EFS
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![BU of 5efs by Molmil](/molmil-images/mine/5efs) | The crystal structure of human kynurenine aminotransferase II | 分子名称: | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 著者 | Nematollahi, A, Sun, G, Kwan, A, Harrop, S.J, Hanrahan, J.R, Nadvi, N.A, Church, W.B. | 登録日 | 2015-10-26 | 公開日 | 2015-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.82503 Å) | 主引用文献 | The crystal structure of human kynurenine aminotransferase II To Be Published
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2FL3
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5CT9
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![BU of 5ct9 by Molmil](/molmil-images/mine/5ct9) | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 5% [BMIM][Cl] | 分子名称: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | 登録日 | 2015-07-23 | 公開日 | 2015-11-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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