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PDB: 3272 件

7L4X
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YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by two six-bp DNA duplexes in P3221 Crystal
分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA w/N6A
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
7L4Y
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YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by Two Six-bp DNA Duplexes in P212121 Crystal
分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA 13mer
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
7L4V
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C-terminal bZIP domain of human C/EBPbeta Bound to DNA with Consensus Recognition with GT Mismatch
分子名称: 1,2-ETHANEDIOL, CCAAT/enhancer-binding protein beta, DNA Strand 1, ...
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations.
Nucleic Acids Res., 49, 2021
2BC5
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Crystal structure of E. coli cytochrome b562 with engineered c-type heme linkages
分子名称: HEME C, SULFATE ION, Soluble cytochrome b562
著者Faraone-Mennella, J, Tezcan, F.A, Gray, H.B, Winkler, J.R.
登録日2005-10-18
公開日2006-09-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Stability and Folding Kinetics of Structurally Characterized Cytochrome c-b(562).
Biochemistry, 45, 2006
2BCE
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CHOLESTEROL ESTERASE FROM BOS TAURUS
分子名称: CHOLESTEROL ESTERASE
著者Chen, J.C.-H, Miercke, L.J.W, Krucinski, J, Starr, J.R, Saenz, G, Wang, X, Spilburg, C.A, Lange, L.G, Ellsworth, J.L, Stroud, R.M.
登録日1998-01-28
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of bovine pancreatic cholesterol esterase at 1.6 A: novel structural features involved in lipase activation.
Biochemistry, 37, 1998
1KMV
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HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (SRI-9662), A LIPOPHILIC ANTIFOLATE
分子名称: (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE, DIHYDROFOLATE REDUCTASE, DIMETHYL SULFOXIDE, ...
著者Klon, A.E, Heroux, A, Ross, L.J, Pathak, V, Johnson, C.A, Piper, J.R, Borhani, D.W.
登録日2001-12-17
公開日2002-07-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution.
J.Mol.Biol., 320, 2002
1KWP
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Crystal Structure of MAPKAP2
分子名称: MAP Kinase Activated Protein Kinase 2, MERCURY (II) ION
著者Meng, W, Swenson, L.L, Fitzgibbon, M.J, Hayakawa, K, ter Haar, E, Behrens, A.E, Fulghum, J.R, Lippke, J.A.
登録日2002-01-30
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinase 2 Suggests a Bifunctional Switch That Couples Kinase Activation with Nuclear Export
J.Biol.Chem., 277, 2002
2ARY
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Catalytic domain of Human Calpain-1
分子名称: BETA-MERCAPTOETHANOL, CALCIUM ION, Calpain-1 catalytic subunit
著者Walker, J.R, Davis, T, Lunin, V, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-08-22
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition
J.Mol.Biol., 366, 2007
7JZ3
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Osmoporin OmpC from E.coli K12
分子名称: Outer membrane protein C
著者Lyu, M, Su, C, Morgan, C.E, Bolla, J.R, Robinson, C.V, Yu, E.W.
登録日2020-09-01
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins.
Nat.Methods, 18, 2021
4MT1
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Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump
分子名称: Drug efflux protein
著者Su, C.-C, Bolla, J.R, Yu, E.W.
登録日2013-09-18
公開日2014-08-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel.
Plos One, 9, 2014
4K07
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Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant
分子名称: Amyloidogenic immunoglobulin light chain protein AL-103, SULFATE ION
著者Thompson, J.R, Berkholz, D.S, Mahlum, E.W, Ramirez-Alvarado, M.
登録日2013-04-03
公開日2013-10-30
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations.
J.Mol.Biol., 426, 2014
4K00
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Crystal structure of Slr0204, a 1,4-dihydroxy-2-naphthoyl-CoA thioesterase from Synechocystis
分子名称: 1,2-ETHANEDIOL, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase
著者Furt, F, Allen, W.J, Widhalm, J.R, Madzelan, P, Rizzo, R.C, Basset, G, Wilson, M.A.
登録日2013-04-03
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis.
Acta Crystallogr.,Sect.D, 69, 2013
2B9E
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Human NSUN5 protein
分子名称: NOL1/NOP2/Sun domain family, member 5 isoform 2, S-ADENOSYLMETHIONINE
著者Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-10-11
公開日2005-10-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Crystal Structure of Human NSUN5 protein in complex with S-adenosyl-L-methionine
To be Published
2B3W
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NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.
分子名称: Hypothetical protein ybiA
著者Ramelot, T.A, Cort, J.R, Xiao, R, Shih, L.Y, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2005-09-21
公開日2005-11-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.
To be Published
2AZH
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Solution structure of iron-sulfur cluster assembly protein SUFU from Bacillus subtilis, with zinc bound at the active site. Northeast Structural Genomics Consortium target SR17
分子名称: SufU, ZINC ION
著者Kornhaber, G.J, Swapna, G.V.T, Ramelot, T.A, Cort, J.R, Aramini, J.M, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2005-09-10
公開日2005-09-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Zn-Ligated Fe-S Cluster Assembly Scaffold Protein SufU From Bacillus subtilis
To be published
2AVD
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Crystal Structure of Human Catechol-O-methyltransferase domain containing 1
分子名称: Catechol-O-methyltransferase, S-ADENOSYLMETHIONINE
著者Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-08-29
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Human Catechol-O-methyltransferase domain containing 1 in complex with S-adenosyl-L-methionine
To be Published
1JIO
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P450eryF/6DEB
分子名称: 6-DEOXYERYTHRONOLIDE B, CYTOCHROME P450 107A1, PROTOPORPHYRIN IX CONTAINING FE
著者Cupp-Vickery, J.R, Garcia, C, Hofacre, A, McGee-Estrada, K.
登録日2001-07-02
公開日2001-10-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF.
J.Mol.Biol., 311, 2001
1JZG
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Pseudomonas aeruginosa Reduced Azurin (Cu1+) Ru(tpy)(phen)(His83)
分子名称: (2,2':6',2'-TERPYRIDINE)-(1,10-PHENANTHROLINE) RUTHENIUM (II), AZURIN, COPPER (I) ION, ...
著者Crane, B.R, Di Bilio, A.J, Winkler, J.R, Gray, H.B.
登録日2001-09-16
公開日2001-10-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Electron tunneling in single crystals of Pseudomonas aeruginosa azurins.
J.Am.Chem.Soc., 123, 2001
1JZJ
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Pseudomonas aeruginosa Azurin Os(bpy)2(im)(His83)
分子名称: COPPER (II) ION, DELTA-BIS(2,2'-BIPYRIDINE)IMIDAZOLE OSMIUM (II), LAMBDA-BIS(2,2'-BIPYRIDINE)IMIDAZOLE OSMIUM (II), ...
著者Crane, B.R, Di Bilio, A.J, Winkler, J.R, Gray, H.B.
登録日2001-09-16
公開日2001-10-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Electron tunneling in single crystals of Pseudomonas aeruginosa azurins.
J.Am.Chem.Soc., 123, 2001
4MAB
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Resolving Cys to Ala variant of Salmonella Alkyl Hydroperoxide Reductase C in its substrate-ready conformation
分子名称: Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, GLYCEROL, ...
著者Perkins, A, Nelson, K.J, Williams, J.R, Poole, L.B, Karplus, P.A.
登録日2013-08-15
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin.
Biochemistry, 52, 2013
1JZF
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Pseudomonas aeruginosa Oxidized Azurin(Cu2+) Ru(tpy)(phen)(His83)
分子名称: (2,2':6',2'-TERPYRIDINE)-(1,10-PHENANTHROLINE) RUTHENIUM (II), AZURIN, COPPER (II) ION, ...
著者Crane, B.R, Di Bilio, A.J, Winkler, J.R, Gray, H.B.
登録日2001-09-16
公開日2001-10-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Electron tunneling in single crystals of Pseudomonas aeruginosa azurins.
J.Am.Chem.Soc., 123, 2001
1JZI
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Pseudomonas aeruginosa Azurin Re(phen)(CO)3(His83)
分子名称: (1,10 PHENANTHROLINE)-(TRI-CARBON MONOXIDE) RHENIUM (I), AZURIN, COPPER (II) ION, ...
著者Crane, B.R, Di Bilio, A.J, Winkler, J.R, Gray, H.B.
登録日2001-09-16
公開日2001-10-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Electron tunneling in single crystals of Pseudomonas aeruginosa azurins.
J.Am.Chem.Soc., 123, 2001
2AWF
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Structure of human Ubiquitin-conjugating enzyme E2 G1
分子名称: Ubiquitin-conjugating enzyme E2 G1
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty, P, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-09-01
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
4LT1
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HEWL co-crystallised with Carboplatin in non-NaCl conditions: crystal 1 processed using the XDS software package
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, Lysozyme C, ...
著者Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Schreurs, A.M.M, Helliwell, J.R.
登録日2013-07-23
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Carboplatin binding to a model protein in non-NaCl conditions to eliminate partial conversion to cisplatin, and the use of different criteria to choose the resolution limit
To be Published
1L6O
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XENOPUS DISHEVELLED PDZ DOMAIN
分子名称: Dapper 1, Segment polarity protein dishevelled homolog DVL-2
著者Cheyette, B.N.R, Waxman, J.S, Miller, J.R, Takemaru, K.-I, Sheldahl, L.C, Khlebtsova, N, Fox, E.P, Earnest, T, Moon, R.T.
登録日2002-03-11
公開日2003-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation
Dev.Cell, 2, 2002

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