8PQL
 
 | | K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide | | 分子名称: | 5-azanylpentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A. | | 登録日 | 2023-07-11 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | | 主引用文献 | Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases.
Nat.Struct.Mol.Biol., 31, 2024
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2WUV
 | | Crystallographic analysis of counter-ion effects on subtilisin enzymatic action in acetonitrile | | 分子名称: | ACETONITRILE, CALCIUM ION, CESIUM ION, ... | | 著者 | Cianci, M, Tomaszewki, B, Helliwell, J.R, Halling, P.J. | | 登録日 | 2009-10-09 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Crystallographic Analysis of Counterion Effects on Subtilisin Enzymatic Action in Acetonitrile.
J.Am.Chem.Soc., 132, 2010
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2YPN
 | | Hydroxymethylbilane synthase | | 分子名称: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, PROTEIN (HYDROXYMETHYLBILANE SYNTHASE) | | 著者 | Nieh, Y.P, Raftery, J, Weisgerber, S, Habash, J, Schotte, F, Ursby, T, Wulff, M, Haedener, A, Campbell, J.W, Hao, Q, Helliwell, J.R. | | 登録日 | 1999-01-11 | | 公開日 | 1999-02-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Accurate and highly complete synchrotron protein crystal Laue diffraction data using the ESRF CCD and the Daresbury Laue software
J.Synchrotron Radiat., 6, 1999
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2VOV
 | | An oxidized tryptophan facilitates copper-binding in Methylococcus capsulatus secreted protein MopE. The structure of wild-type MopE to 1.35AA | | 分子名称: | CALCIUM ION, COPPER (II) ION, SURFACE-ASSOCIATED PROTEIN | | 著者 | Helland, R, Fjellbirkeland, A, Karlsen, O.A, Ve, T, Lillehaug, J.R, Jensen, H.B. | | 登録日 | 2008-02-22 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | An Oxidized Tryptophan Facilitates Copper Binding in Methylococcus Capsulatus-Secreted Protein Mope.
J.Biol.Chem., 283, 2008
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2W6N
 | |
2VYQ
 | | FERREDOXIN:NADP REDUCTASE MUTANT WITH THR 155 REPLACED BY GLY, ALA 160 REPLACED BY THR, LEU 263 REPLACED BY PRO AND TYR 303 REPLACED BY SER (T155G-A160T-L263P-Y303S) | | 分子名称: | FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Peregrina, J.R, Medina, M. | | 登録日 | 2008-07-28 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Protein Motifs Involved in Coenzyme Interaction and Enzymatic Efficiency in Anabaena Ferredoxin-Nadp+ Reductase.
Biochemistry, 48, 2009
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2WYG
 | | Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs | | 分子名称: | (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1R)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, FACTOR X LIGHT CHAIN | | 著者 | Kleanthous, S, Borthwick, A.D, Brown, D, Burns-Kurtis, C.L, Campbell, M, Chaudry, L, Chan, C, Clarte, M, Convery, M.A, Harling, J.D, Hortense, E, Irving, W.R, Irvine, S, Pateman, A.J, Patikis, A, Pinto, I.L, Pollard, D.R, Roethka, T.J, Senger, S, Shah, G.P, Stelman, G.J, Toomey, J.R, Watson, N.S, Whittaker, C, Zhou, P, Young, R.J. | | 登録日 | 2009-11-16 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Monoaryl P4 Motifs
Bioorg.Med.Chem.Lett., 20, 2010
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2XL3
 | | WDR5 IN COMPLEX WITH AN RBBP5 PEPTIDE AND HISTONE H3 PEPTIDE | | 分子名称: | GLYCEROL, HISTONE H3.1, RETINOBLASTOMA-BINDING PROTEIN 5, ... | | 著者 | Odho, Z, Southall, S.M, Wilson, J.R. | | 登録日 | 2010-07-19 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Characterisation of a Novel Wdr5 Binding Site that Recruits Rbbp5 Through a Conserved Motif and Enhances Methylation of H3K4 by Mll1.
J.Biol.Chem., 285, 2010
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2X62
 | | CRYSTAL STRUCTURE OF THE SIALYLTRANSFERASE CST-II Y81F IN COMPLEX WITH CMP | | 分子名称: | 1,2-ETHANEDIOL, ALPHA-2,3-/2,8-SIALYLTRANSFERASE, N3-PROTONATED CYTIDINE-5'-MONOPHOSPHATE | | 著者 | Lee, H.J, Lairson, L.L, Rich, J.R, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | | 登録日 | 2010-02-14 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II from Campylobacter Jejuni.
J.Biol.Chem., 286, 2011
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2WYJ
 | | Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs | | 分子名称: | (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, FACTOR X LIGHT CHAIN | | 著者 | Kleanthous, S, Borthwick, A.D, Brown, D, Burns-Kurtis, C.L, Campbell, M, Chaudry, L, Chan, C, Clarte, M, Convery, M.A, Harling, J.D, Hortense, E, Irving, W.R, Irvine, S, Pateman, A.J, Patikis, A, Pinto, I.L, Pollard, D.R, Roethka, T.J, Senger, S, Shah, G.P, Stelman, G.J, Toomey, J.R, Watson, N.S, Whittaker, C, Zhou, P, Young, R.J. | | 登録日 | 2009-11-16 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Monoaryl P4 Motifs
Bioorg.Med.Chem.Lett., 20, 2010
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8SA2
 | | Adenosylcobalamin-bound riboswitch dimer, form 1 | | 分子名称: | Adenosylcobalamin, adenosylcobalamin riboswitch form 1 | | 著者 | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | | 登録日 | 2023-03-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
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8SA4
 | | Adenosylcobalamin-bound riboswitch dimer, form 3 | | 分子名称: | Adenosylcobalamin, adenosylcobalamin riboswitch form 3 | | 著者 | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | | 登録日 | 2023-03-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
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8S9M
 | | DNA cytosine-N4 methyltransferase (residues 79-324) from the Bdelloid rotifer Adineta vaga | | 分子名称: | 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN | | 著者 | Zhou, J, Horton, J.R, Cheng, X. | | 登録日 | 2023-03-29 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga.
J.Biol.Chem., 299, 2023
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8SA3
 | | Adenosylcobalamin-bound riboswitch dimer, form 2 | | 分子名称: | Adenosylcobalamin, adenosylcobalamin riboswitch form 2 | | 著者 | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | | 登録日 | 2023-03-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
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8SA6
 | | apo form of adenosylcobalamin riboswitch dimer | | 分子名称: | apo form of adenosylcobalamin riboswitch dimer | | 著者 | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | | 登録日 | 2023-03-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | | 主引用文献 | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
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8SA5
 | | Adenosylcobalamin-bound riboswitch dimer, form 4 | | 分子名称: | Adenosylcobalamin, adenosylcobalamin riboswitch form 4 | | 著者 | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | | 登録日 | 2023-03-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
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8SSQ
 | | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 35mer DNA 35-4 | | 分子名称: | DNA (35-MER) Strand 2, DNA (35-MER) Strand I, SODIUM ION, ... | | 著者 | Horton, J.R, Yang, J, Cheng, X. | | 登録日 | 2023-05-08 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
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8SSR
 | | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 35mer DNA 35-20 | | 分子名称: | DNA (35-MER) Strand I, DNA (35-MER) Strand II, SODIUM ION, ... | | 著者 | Horton, J.R, Yang, J, Cheng, X. | | 登録日 | 2023-05-08 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | | 主引用文献 | Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
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8S9N
 | | DNA cytosine-N4 methyltransferase (residues 61-324) from the Bdelloid rotifer Adineta vaga - C2 crystal form | | 分子名称: | 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN | | 著者 | Zhou, J, Horton, J.R, Cheng, X. | | 登録日 | 2023-03-29 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga.
J.Biol.Chem., 299, 2023
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8S9O
 | | DNA cytosine-N4 methyltransferase (residues 61-324) from the Bdelloid rotifer Adineta vaga - P1 crystal form | | 分子名称: | 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN | | 著者 | Zhou, J, Horton, J.R, Cheng, X. | | 登録日 | 2023-03-29 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga.
J.Biol.Chem., 299, 2023
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2W70
 | |
2VZL
 | | FERREDOXIN-NADP REDUCTASE (MUTATIONS: T155G, A160T, L263P AND Y303S) COMPLEXED WITH NAD BY COCRYSTALLIZATION | | 分子名称: | FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Peregrina, J.R, Medina, M. | | 登録日 | 2008-07-28 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Protein Motifs Involved in Coenzyme Interaction and Enzymatic Efficiency in Anabaena Ferredoxin-Nadp+ Reductase.
Biochemistry, 48, 2009
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8Q7R
 | | Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide | | 分子名称: | 5-azanyl-1-oxidanyl-pentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A. | | 登録日 | 2023-08-16 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
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2X3U
 | | Ferredoxin-NADP reductase mutant with Tyr 303 replaced by Phe (Y303F) | | 分子名称: | FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Peregrina, J.R, Sanchez-Azqueta, A, Medina, M. | | 登録日 | 2010-01-27 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Role of Specific Residues in Coenzyme Binding, Charge-Transfer Complex Formation, and Catalysis in Anabaena Ferredoxin Nadp(+)-Reductase.
Biochim.Biophys.Acta, 1797, 2010
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8SO0
 | | Cryo-EM structure of the PP2A:B55-FAM122A complex | | 分子名称: | FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, ... | | 著者 | Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. | | 登録日 | 2023-04-28 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.79961 Å) | | 主引用文献 | Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
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