3ZDE
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![BU of 3zde by Molmil](/molmil-images/mine/3zde) | Potassium free structure of E. coli ExoIX | Descriptor: | PROTEIN XNI | Authors: | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | Deposit date: | 2012-11-26 | Release date: | 2013-07-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases Nucleic Acids Res., 41, 2013
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3ZDB
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![BU of 3zdb by Molmil](/molmil-images/mine/3zdb) | Structure of E. coli ExoIX in complex with the palindromic 5ov4 DNA oligonucleotide, di-magnesium and potassium | Descriptor: | 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ACETATE ION, ... | Authors: | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | Deposit date: | 2012-11-26 | Release date: | 2013-07-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases Nucleic Acids Res., 41, 2013
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3ZZ9
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![BU of 3zz9 by Molmil](/molmil-images/mine/3zz9) | Crystal structure of 3C protease of coxsackievirus B3 complexed with alpha, beta-unsaturated ethyl ester inhibitor 83 | Descriptor: | 3C PROTEINASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(2-TERT-BUTOXY-2-OXOETHYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE | Authors: | Tan, J, Anand, K, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2011-08-31 | Release date: | 2012-09-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations To be Published
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3ZDD
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![BU of 3zdd by Molmil](/molmil-images/mine/3zdd) | Structure of E. coli ExoIX in complex with the palindromic 5ov6 oligonucleotide and potassium | Descriptor: | 1,2-ETHANEDIOL, 5OV6 DNA, ISOPROPYL ALCOHOL, ... | Authors: | Flemming, C.S, Hemsworth, G.R, Anstey-Gilbert, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | Deposit date: | 2012-11-26 | Release date: | 2013-07-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of Escherichia coli ExoIX--implications for DNA binding and catalysis in flap endonucleases. Nucleic Acids Res., 41, 2013
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3ZZ6
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![BU of 3zz6 by Molmil](/molmil-images/mine/3zz6) | Crystal structure of 3C protease of coxsackievirus B3 complexed with Michael receptor inhibitor 75 | Descriptor: | ETHYL (4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE, POLYPROTEIN 3BCD | Authors: | Tan, J, Anand, K, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2011-08-31 | Release date: | 2012-09-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Peptidic Ab-Nonsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations To be Published
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1IUK
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![BU of 1iuk by Molmil](/molmil-images/mine/1iuk) | The structure of native ID.343 from Thermus thermophilus | Descriptor: | hypothetical protein TT1466 | Authors: | Wada, T, Shirouzu, M, Park, S.-Y, Tame, J.R, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-03-05 | Release date: | 2003-07-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of a conserved CoA-binding protein synthesized by a cell-free system. Acta Crystallogr.,Sect.D, 59, 2003
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1IY7
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![BU of 1iy7 by Molmil](/molmil-images/mine/1iy7) | Crystal Structure of CPA and sulfamide-based inhibitor complex | Descriptor: | Carboxypeptidase A, PHENYLALANINE-N-SULFONAMIDE, ZINC ION | Authors: | Kim, S.J, Woo, J.R, Park, J.D, Kim, D.H, Ryu, S.E. | Deposit date: | 2002-07-24 | Release date: | 2003-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Sulfamide-Based Inhibitors for Carboxypeptidase A. Novel Type Transition State Analogue Inhibitors for Zinc Proteases J.Med.Chem., 45, 2002
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3ZD8
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![BU of 3zd8 by Molmil](/molmil-images/mine/3zd8) | Potassium bound structure of E. coli ExoIX in P1 | Descriptor: | POTASSIUM ION, PROTEIN XNI | Authors: | Anstey-Gilbert, C.S, Hemsworth, G.R, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | Deposit date: | 2012-11-26 | Release date: | 2013-07-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases Nucleic Acids Res., 41, 2013
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1KMV
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![BU of 1kmv by Molmil](/molmil-images/mine/1kmv) | HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (SRI-9662), A LIPOPHILIC ANTIFOLATE | Descriptor: | (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE, DIHYDROFOLATE REDUCTASE, DIMETHYL SULFOXIDE, ... | Authors: | Klon, A.E, Heroux, A, Ross, L.J, Pathak, V, Johnson, C.A, Piper, J.R, Borhani, D.W. | Deposit date: | 2001-12-17 | Release date: | 2002-07-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution. J.Mol.Biol., 320, 2002
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4A82
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![BU of 4a82 by Molmil](/molmil-images/mine/4a82) | Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966. | Descriptor: | CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Authors: | Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C. | Deposit date: | 2011-11-18 | Release date: | 2012-01-11 | Last modified: | 2024-05-08 | Method: | ELECTRON CRYSTALLOGRAPHY (9 Å) | Cite: | The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate. J.Biol.Chem., 286, 2011
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1KWP
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![BU of 1kwp by Molmil](/molmil-images/mine/1kwp) | Crystal Structure of MAPKAP2 | Descriptor: | MAP Kinase Activated Protein Kinase 2, MERCURY (II) ION | Authors: | Meng, W, Swenson, L.L, Fitzgibbon, M.J, Hayakawa, K, ter Haar, E, Behrens, A.E, Fulghum, J.R, Lippke, J.A. | Deposit date: | 2002-01-30 | Release date: | 2002-09-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinase 2 Suggests a Bifunctional Switch That
Couples Kinase Activation with Nuclear Export J.Biol.Chem., 277, 2002
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1PAA
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![BU of 1paa by Molmil](/molmil-images/mine/1paa) | STRUCTURE OF A HISTIDINE-X4-HISTIDINE ZINC FINGER DOMAIN: INSIGHTS INTO ADR1-UAS1 PROTEIN-DNA RECOGNITION | Descriptor: | YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION | Authors: | Bernstein, B.E, Hoffman, R.C, Horvath, S.J, Herriott, J.R, Klevit, R.E. | Deposit date: | 1994-07-15 | Release date: | 1994-10-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition. Biochemistry, 33, 1994
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1KMS
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![BU of 1kms by Molmil](/molmil-images/mine/1kms) | HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 6-([5-QUINOLYLAMINO]METHYL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (SRI-9439), A LIPOPHILIC ANTIFOLATE | Descriptor: | 6-([5-QUINOLYLAMINO]METHYL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Klon, A.E, Heroux, A, Ross, L.J, Pathak, V, Johnson, C.A, Piper, J.R, Borhani, D.W. | Deposit date: | 2001-12-17 | Release date: | 2002-07-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution. J.Mol.Biol., 320, 2002
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1OXA
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![BU of 1oxa by Molmil](/molmil-images/mine/1oxa) | CYTOCHROME P450 (DONOR:O2 OXIDOREDUCTASE) | Descriptor: | 6-DEOXYERYTHRONOLIDE B, CYTOCHROME P450 ERYF, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Cupp-Vickery, J.R, Poulos, T.L. | Deposit date: | 1995-07-14 | Release date: | 1995-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of cytochrome P450eryF involved in erythromycin biosynthesis. Nat.Struct.Biol., 2, 1995
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1UA0
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![BU of 1ua0 by Molmil](/molmil-images/mine/1ua0) | Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase | Descriptor: | 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... | Authors: | Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. | Deposit date: | 2004-08-11 | Release date: | 2004-09-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279, 2004
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1UA1
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![BU of 1ua1 by Molmil](/molmil-images/mine/1ua1) | Structure of aminofluorene adduct paired opposite cytosine at the polymerase active site. | Descriptor: | 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... | Authors: | Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. | Deposit date: | 2004-08-11 | Release date: | 2004-09-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279, 2004
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4RNV
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![BU of 4rnv by Molmil](/molmil-images/mine/4rnv) | G303 Circular Permutation of Old Yellow Enzyme with the Inhibitor p-Hydroxybenzaldehyde | Descriptor: | FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1, P-HYDROXYBENZALDEHYDE | Authors: | Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S. | Deposit date: | 2014-10-26 | Release date: | 2015-01-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.473 Å) | Cite: | STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME. ACS Catal, 5, 2015
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2KRJ
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![BU of 2krj by Molmil](/molmil-images/mine/2krj) | High-Resolution Solid-State NMR Structure of a 17.6 kDa Protein | Descriptor: | COBALT (II) ION, Macrophage metalloelastase | Authors: | Bertini, I, Bhaumik, A, De Pa pe, G, Griffin, R.G, Lelli, M, Lewandowski, J.R, Luchinat, C. | Deposit date: | 2009-12-18 | Release date: | 2010-02-23 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR | Cite: | High-resolution solid-state NMR structure of a 17.6 kDa protein. J.Am.Chem.Soc., 132, 2010
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8Y6C
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![BU of 8y6c by Molmil](/molmil-images/mine/8y6c) | Norovirus GII.10 P domain and 2'-FL (powder) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GII.10 norovirus P domain in complex with 2'FL (powder), ... | Authors: | Hansman, G, Tame, J.R.H, Kher, G, Pancera, M. | Deposit date: | 2024-02-02 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Norovirus GII.10 P domain and 2'-FL (powder) To Be Published
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8WEY
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![BU of 8wey by Molmil](/molmil-images/mine/8wey) | PSI-LHCI of the red alga Cyanidium caldarium RK-1 (NIES-2137) | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{R} )-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... | Authors: | Kato, K, Hamaguchi, T, Nakajima, Y, Kawakami, K, Yonekura, K, Shen, J.R, Nagao, R. | Deposit date: | 2023-09-19 | Release date: | 2024-02-14 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (1.92 Å) | Cite: | The structure of PSI-LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red-lineage LHCs. Proc.Natl.Acad.Sci.USA, 121, 2024
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2FHD
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![BU of 2fhd by Molmil](/molmil-images/mine/2fhd) | Crystal structure of Crb2 tandem tudor domains | Descriptor: | DNA repair protein rhp9/CRB2, PHOSPHATE ION | Authors: | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | Deposit date: | 2005-12-23 | Release date: | 2007-01-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell(Cambridge,Mass.), 127, 2006
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9FLA
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![BU of 9fla by Molmil](/molmil-images/mine/9fla) | |
9CL9
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![BU of 9cl9 by Molmil](/molmil-images/mine/9cl9) | WT 12C IM fraction, B-b3 with RluB bound | Descriptor: | 23S rRNA, Large ribosomal subunit protein bL20, Large ribosomal subunit protein bL21, ... | Authors: | Lee, J, Sheng, K, Williamson, J.R. | Deposit date: | 2024-07-10 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (5.04 Å) | Cite: | 50S ribosome assembly intermediates at low temperature reveal bound RluB To Be Published
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2F9K
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![BU of 2f9k by Molmil](/molmil-images/mine/2f9k) | Crystal structure of human FPPS in complex with Zoledronate and Zn2+ | Descriptor: | Farnesyl Diphosphate Synthase, PHOSPHATE ION, ZINC ION, ... | Authors: | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | Deposit date: | 2005-12-06 | Release date: | 2006-02-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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8Y6D
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![BU of 8y6d by Molmil](/molmil-images/mine/8y6d) | Norovirus GII.10 P domain and 2'-FL (tablet) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GII.10 norovirus P domain in complex with 2'-FL (tablet), ... | Authors: | Hansman, G, Tame, J.R.H, Kher, G, Pancera, M. | Deposit date: | 2024-02-02 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Norovirus GII.10 P domain and 2'-FL (tablet) To Be Published
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