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PDB: 3278 件

3CUX
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Atomic Resolution Structures of Escherichia coli and Bacillis anthracis Malate Synthase A: Comparison with Isoform G and Implications for Structure Based Drug Design
分子名称: MAGNESIUM ION, Malate synthase
著者Lohman, J.R, Remington, S.J.
登録日2008-04-17
公開日2008-11-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Atomic resolution structures of Escherichia coli and Bacillus anthracis malate synthase A: comparison with isoform G and implications for structure-based drug discovery
Protein Sci., 17, 2008
5EYV
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Crystal Structure of Adenylosuccinate lyase from Schistosoma mansoni in APO form.
分子名称: Adenylosuccinate lyase
著者Romanello, L, Torini, J.R, Bird, L.E, Nettleship, J.E, Owens, R.J, Reddivari, Y, Brandao-Neto, J, Pereira, H.M.
登録日2015-11-25
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Mol. Biochem. Parasitol., 214, 2017
8DVW
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Structure of the Campylobacter concisus glycosyltransferase PglA R203Q
分子名称: N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
著者Vuksanovic, N, Clasman, J.R, Bernstein, H.M, Imperiali, B, Allen, K.N.
登録日2022-07-30
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA.
Protein Sci., 33, 2024
8DVZ
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Structure of the Campylobacter concisus glycosyltransferase PglA R282V variant
分子名称: N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
著者Vuksanovic, N, Clasman, J.R, Bernstein, H.M, Imperiali, B, Allen, K.N.
登録日2022-07-30
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA.
Protein Sci., 33, 2024
4L6I
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Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine
分子名称: ADENINE, S-methyl-5'-thioadenosine phosphorylase, SULFATE ION
著者Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M.
登録日2013-06-12
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.
Plos Negl Trop Dis, 10, 2016
8DQD
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Structure of the Campylobacter concisus glycosyltransferase PglA
分子名称: N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
著者Vuksanovic, N, Clasman, J.R, Bernstein, H.M, Imperiali, B, Allen, K.N.
登録日2022-07-18
公開日2024-01-17
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA.
Protein Sci., 33, 2024
5EZQ
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Venezuelan Equine Encephalitis Virus (VEEV) Nonstructural protein 2 (nsP2) Cysteine Protease
分子名称: Non-structural Protein 2 Cysteine Protease
著者Compton, J.R, Legler, P.M.
登録日2015-11-26
公開日2016-04-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Kinetic, Mutational, and Structural Studies of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease.
Biochemistry, 55, 2016
7N5S
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ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6)
分子名称: DNA Strand I, DNA Strand II, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
7N5T
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ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5)
分子名称: DNA Strand I, DNA Strand II, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
8EW3
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Cryo EM structure of Vibrio cholerae NQR
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Na(+)-translocating NADH-quinone reductase subunit A, ...
著者Fuller, J.R, Juarez, O.
登録日2022-10-21
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (2.65159 Å)
主引用文献Novel cofactor binding motifs, electron transfer and ion pumping mechanisms of the respiratory complex NQR
To Be Published
5BX4
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Crystal structure of Thermoanaerobacterium xylanolyticum GH116 beta-glucosidase with Glucoimidazole
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLUCOIMIDAZOLE, ...
著者Charoenwattanasatien, R, Pengthaisong, S, Sansenya, S, Mutoh, R, Tankrathok, A, Tanaka, H, Kurisu, G, Ketudat Cairns, J.R.
登録日2015-06-08
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
3CGD
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BU of 3cgd by Molmil
Pyridine Nucleotide Complexes with Bacillus anthracis Coenzyme A-Disulfide Reductase: A Structural Analysis of Dual NAD(P)H Specificity
分子名称: COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Wallen, J.R.
登録日2008-03-05
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Pyridine Nucleotide Complexes with Bacillus anthracis Coenzyme A-Disulfide Reductase: A Structural Analysis of Dual NAD(P)H Specificity.
Biochemistry, 47, 2008
8EVU
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BU of 8evu by Molmil
Cryo EM structure of Vibrio cholerae NQR
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Na(+)-translocating NADH-quinone reductase subunit A, ...
著者Fuller, J.R, Juarez, O.
登録日2022-10-20
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (2.5804 Å)
主引用文献Novel cofactor binding motifs, electron transfer and ion pumping mechanisms of the respiratory complex NQR
To Be Published
3CLZ
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BU of 3clz by Molmil
The set and ring associated (SRA) domain of UHRF1 bound to methylated DNA
分子名称: 5'-D(*DCP*DCP*DCP*DTP*DGP*DCP*DGP*DGP*DGP*DCP*DCP*DC)-3', 5'-D(*DGP*DGP*DGP*DCP*DCP*(5CM)P*DGP*DCP*DAP*DGP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1
著者Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-03-20
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
Nature, 455, 2008
8EW6
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BU of 8ew6 by Molmil
Anti-human CD8 VHH complex with CD8 alpha
分子名称: Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain
著者Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P.
登録日2022-10-21
公開日2022-11-23
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging.
Eur J Nucl Med Mol Imaging, 50, 2023
5BX2
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BU of 5bx2 by Molmil
Crystal structure of Thermoanaerobacterium xylanolyticum GH116 beta-glucosidase with 2-deoxy-2-fluoroglucoside
分子名称: 1,2-ETHANEDIOL, 2-deoxy-2-fluoro-alpha-D-glucopyranose, CALCIUM ION, ...
著者Charoenwattanasatien, R, Pengthaisong, S, Sansenya, S, Mutoh, R, Tanaka, H, Kurisu, G, Ketudat Cairns, J.R.
登録日2015-06-08
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
4G2K
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BU of 4g2k by Molmil
Crystal structure of the Marburg Virus GP2 ectodomain in its post-fusion conformation
分子名称: CHLORIDE ION, GLYCEROL, General control protein GCN4, ...
著者Malashkevich, V.N, Koellhoffer, J.F, Harrison, J.S, Toro, R, Bhosle, R.C, Chandran, K, Lai, J.R, Almo, S.C.
登録日2012-07-12
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Marburg Virus GP2 Core Domain in Its Postfusion Conformation.
Biochemistry, 51, 2012
8EOP
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BU of 8eop by Molmil
Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-10-04
公開日2022-12-21
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
3CV1
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BU of 3cv1 by Molmil
Atomic Resolution Structures of Escherichia coli and Bacillis anthracis Malate Synthase A: Comparison with Isoform G and Implications for Structure Based Drug Design
分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ...
著者Lohman, J.R.
登録日2008-04-17
公開日2008-11-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Atomic resolution structures of Escherichia coli and Bacillus anthracis malate synthase A: comparison with isoform G and implications for structure-based drug discovery
Protein Sci., 17, 2008
5C7M
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BU of 5c7m by Molmil
CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT
分子名称: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C
著者Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
登録日2015-06-24
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
4FZ5
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Crystal Structure of Human TIRAP TIR-domain
分子名称: Toll/interleukin-1 receptor domain-containing adapter protein
著者Woo, J.R, Kim, S, Shoelson, S.E, Park, S.
登録日2012-07-06
公開日2013-05-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献X-ray Crystallographic Structure of TIR-Domain from the Human TIR-Domain Containing Adaptor Protein/MyD88 Adaptor-Like Protein (TIRAP/MAL)
Bull.Korean Chem.Soc., 33, 2013
8F8Y
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PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
4L5A
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BU of 4l5a by Molmil
Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with tubercidin
分子名称: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, S-methyl-5'-thioadenosine phosphorylase, SULFATE ION
著者Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M.
登録日2013-06-10
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2993 Å)
主引用文献Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.
Plos Negl Trop Dis, 10, 2016
8F8Z
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PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, H3 N-Terminal Peptide, Lysine-specific demethylase PHF2, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
7MYO
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Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719
分子名称: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
著者Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K.
登録日2021-05-21
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation.
Proc.Natl.Acad.Sci.USA, 118, 2021

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