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PDB: 5587 件

1XQ7
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Cyclophilin from Trypanosoma cruzi bound to cyclosporin A
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
著者Caruthers, J.M, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-10-11
公開日2004-12-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Cyclophilin from Trypanosoma Cruzi Bound to Cyclosporin A
To be Published
1XUH
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TRYPSIN-KETO-BABIM-CO+2, PH 8.2
分子名称: BIS(5-AMIDINO-2-BENZIMIDAZOLYL)METHANONE, CALCIUM ION, COBALT (II) ION, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
6GSD
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BU of 6gsd by Molmil
Plantago Major multifunctional oxidoreductase in complex with progesterone and NADP+
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROGESTERONE, Progesterone 5-beta-reductase
著者Fellows, R, Silva, C, Russo, C.M, Lee, S.G, Jez, J.M, Chisholm, J.D, Zubieta, C, Nanao, M.
登録日2018-06-14
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily.
Sci Rep, 8, 2018
6FLB
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3H5 Fab bound to EDIII of DenV 2 Xtal form 2
分子名称: CHLORIDE ION, Domain III of Dengue virus 2, GLYCEROL, ...
著者Flanagan, A, Renner, M, Grimes, J.M.
登録日2018-01-25
公開日2018-10-24
最終更新日2018-10-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus.
Nat. Immunol., 19, 2018
4ESJ
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RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA
分子名称: AZIDE ION, DNA (5'-D(*CP*TP*GP*GP*(6MA)P*TP*CP*CP*AP*G)-3'), GLYCEROL, ...
著者Siwek, W, Czapinska, H, Bochtler, M, Bujnicki, J.M, Skowronek, K.
登録日2012-04-23
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Nucleic Acids Res., 40, 2012
1XL4
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Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1
分子名称: Inward rectifier potassium channel, MAGNESIUM ION, POTASSIUM ION
著者Gulbis, J.M, Kuo, A, Smith, B, Doyle, D.A, Edwards, A, Arrowsmith, C, Sundstrom, M.
登録日2004-09-30
公開日2004-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Two intermediate gating state crystal structures of the KirBac3.1 K+ channel
To be Published
3BD6
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BU of 3bd6 by Molmil
Glycogen Phosphorylase complex with 1(-D-ribofuranosyl) cyanuric acid
分子名称: 1-beta-D-ribofuranosyl-1,3,5-triazinane-2,4,6-trione, Glycogen phosphorylase, muscle form
著者Sovantzis, D.A, Hadjiloi, T, Hayes, J.M, Zographos, S.E, Chrysina, E.D, Oikonomakos, N.G.
登録日2007-11-14
公開日2008-11-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献D-Glucopyranosyl pyrimidine nucleoside binding to muscle glycogen phosphorylase b
To be Published
1XUJ
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TRYPSIN-KETO-BABIM-ZN+2, PH 8.2
分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANONE ZINC, CALCIUM ION, SULFATE ION, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
6FLC
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2C8 Fab bound to EDIII of DenV 2
分子名称: Domain III of Dengue virus 2, GLYCEROL, Heavy chain of 2C8 Fab, ...
著者Flanagan, A, Renner, M, Grimes, J.M.
登録日2018-01-25
公開日2018-10-24
最終更新日2018-10-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus.
Nat. Immunol., 19, 2018
1XL6
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Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1
分子名称: Inward rectifier potassium channel, MAGNESIUM ION, POTASSIUM ION, ...
著者Gulbis, J.M, Kuo, A, Smith, B, Doyle, D.A, Edwards, A, Arrowsmith, C, Sundstrom, M.
登録日2004-09-30
公開日2004-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Two intermediate gating state crystal structures of the KirBac3.1 K+ channel
To be Published
3B2N
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Crystal structure of DNA-binding response regulator, LuxR family, from Staphylococcus aureus
分子名称: SODIUM ION, Uncharacterized protein Q99UF4
著者Malashkevich, V.N, Toro, R, Meyer, A.J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-10-18
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of DNA-binding response regulator, LuxR family, from Staphylococcus aureus.
To be Published
1XPO
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BU of 1xpo by Molmil
Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin
分子名称: 5'-R(*CP*UP*CP*UP*CP*UP*CP*U)-3', BICYCLOMYCIN, MAGNESIUM ION, ...
著者Skordalakes, E, Brogan, A.P, Park, B.S, Kohn, H, Berger, J.M.
登録日2004-10-09
公開日2005-02-08
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural mechanism of inhibition of the rho transcription termination factor by the antibiotic bicyclomycin
Structure, 13, 2005
6FLA
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3H5 Fab bound to EDIII of DenV 2 Xtal form 1
分子名称: CHLORIDE ION, Domain III of Dengue virus 2, GLYCEROL, ...
著者Flanagan, A, Renner, M, Grimes, J.M.
登録日2018-01-25
公開日2018-10-24
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus.
Nat. Immunol., 19, 2018
4F08
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Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
分子名称: 1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
著者Murray, J.M.
登録日2012-05-03
公開日2012-07-04
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2.
J.Med.Chem., 55, 2012
3BG2
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BU of 3bg2 by Molmil
Crystal structure of deoxyguanosinetriphosphate triphosphohydrolase from Flavobacterium sp. MED217
分子名称: DGTP triphosphohydrolase
著者Fedorov, A.A, Fedorov, E.V, Toro, R, Meyer, A.J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-11-25
公開日2007-12-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the deoxyguanosinetriphosphate triphosphohydrolase from Flavobacterium sp. MED217.
To be Published
3BGF
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BU of 3bgf by Molmil
X-ray crystal structure of the SARS coronavirus spike receptor binding domain in complex with F26G19 Fab
分子名称: F26G19 Fab, Spike protein S1
著者Pak, J.E, Rini, J.M.
登録日2007-11-26
公開日2008-12-02
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into immune recognition of the severe acute respiratory syndrome coronavirus S protein receptor binding domain.
J.Mol.Biol., 388, 2009
4BZW
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BU of 4bzw by Molmil
Complete crystal structure of the carboxylesterase Cest-2923 (lp_2923) from Lactobacillus plantarum WCFS1
分子名称: ACETATE ION, LIPASE/ESTERASE, SULFATE ION, ...
著者Benavente, R, Esteban-Torres, M, Acebron, I, delasRivas, B, Munoz, R, Alvarez, Y, Mancheno, J.M.
登録日2013-07-30
公開日2013-10-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Structure, Biochemical Characterization and Analysis of the Pleomorphism of Carboxylesterase Cest-2923 from Lactobacillus Plantarum Wcfs1
FEBS J., 280, 2013
3B1V
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Crystal structure of an S. thermophilus NFeoB E67A mutant bound to mGMPPNP
分子名称: 3'-O-(N-methylanthraniloyl)-beta:gamma-imidoguanosine-5'-triphosphate, CHLORIDE ION, Ferrous iron uptake transporter protein B, ...
著者Ash, M.R, Maher, M.J, Guss, J.M, Jormakka, M.
登録日2011-07-15
公開日2011-11-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A suite of Switch I and Switch II mutant structures from the G-protein domain of FeoB
Acta Crystallogr.,Sect.D, 67, 2011
4BQU
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Japanin from Rhipicephalus appendiculatus bound to cholesterol: Orthorhombic crystal form
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M.
登録日2013-06-02
公開日2014-06-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks.
Sci Rep, 7, 2017
3B4T
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Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340
分子名称: PHOSPHATE ION, Ribonuclease PH
著者Antczak, A.J, Berger, J.M, Lekin, T, Segelke, B.W, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB), TB Structural Genomics Consortium (TBSGC)
登録日2007-10-24
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献2.1 A Crystal structure of RNase PH from Mycobacterium tuberculosis.
To be Published
3BJS
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Crystal structure of a member of enolase superfamily from Polaromonas sp. JS666
分子名称: MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme
著者Patskovsky, Y, Bonanno, J.B, Ozyurt, S, Dickey, M, Sauder, J.M, Reyes, C, Groshong, C, Gheyi, T, Smith, D, Wasserman, S.R, Gerlt, J, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-12-04
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of a Member of Enolase Superfamily from Polaromonas sp. JS666.
To be Published
3B8Z
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High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2)
分子名称: CALCIUM ION, N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide, ZINC ION, ...
著者Shieh, H.-S, Williams, J.M, Mathis, K.J, Tortorella, M.D, Tomasselli, A.
登録日2007-11-02
公開日2007-12-11
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2).
J.Biol.Chem., 283, 2008
3B1Z
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Crystal structure of an S. thermophilus NFeoB T35S mutant without nucleotide
分子名称: Ferrous iron uptake transporter protein B, SULFATE ION
著者Ash, M.R, Maher, M.J, Guss, J.M, Jormakka, M.
登録日2011-07-15
公開日2011-11-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A suite of Switch I and Switch II mutant structures from the G-protein domain of FeoB
Acta Crystallogr.,Sect.D, 67, 2011
1XYR
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Poliovirus 135S cell entry intermediate
分子名称: Genome polyprotein, Coat protein VP1, Coat protein VP2, ...
著者Bubeck, D, Filman, D.J, Cheng, N, Steven, A.C, Hogle, J.M, Belnap, D.M.
登録日2004-11-10
公開日2005-08-02
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes.
J.Virol., 79, 2005
1XUK
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TRYPSIN-BABIM-SULFATE, PH 5.9
分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE, CALCIUM ION, SULFATE ION, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-11-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998

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