3B8Z
High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2)
Summary for 3B8Z
Entry DOI | 10.2210/pdb3b8z/pdb |
Descriptor | protein ADAMTS-5, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | alpha/beta, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix : Q9UNA0 |
Total number of polymer chains | 2 |
Total formula weight | 49330.38 |
Authors | Shieh, H.-S.,Williams, J.M.,Mathis, K.J.,Tortorella, M.D.,Tomasselli, A. (deposition date: 2007-11-02, release date: 2007-12-11, Last modification date: 2021-10-20) |
Primary citation | Shieh, H.S.,Mathis, K.J.,Williams, J.M.,Hills, R.L.,Wiese, J.F.,Benson, T.E.,Kiefer, J.R.,Marino, M.H.,Carroll, J.N.,Leone, J.W.,Malfait, A.M.,Arner, E.C.,Tortorella, M.D.,Tomasselli, A. High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2). J.Biol.Chem., 283:1501-1507, 2008 Cited by PubMed: 17991750DOI: 10.1074/jbc.M705879200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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