2E6L
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![BU of 2e6l by Molmil](/molmil-images/mine/2e6l) | structure of mouse WRN exonuclease domain | 分子名称: | SULFATE ION, Werner syndrome ATP-dependent helicase homolog, ZINC ION | 著者 | Cho, Y, Choi, J.M. | 登録日 | 2006-12-27 | 公開日 | 2007-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | probing the roles of active site residues in 3'-5' exonuclease of werner syndrome protein TO BE PUBLISHED
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6PTL
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8SLZ
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![BU of 8slz by Molmil](/molmil-images/mine/8slz) | |
7OI2
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![BU of 7oi2 by Molmil](/molmil-images/mine/7oi2) | SaFtsz complexed with GDP (NaCl purification) | 分子名称: | 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu Morales, J.M. | 登録日 | 2021-05-11 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics. Plos Biol., 20, 2022
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4UOI
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![BU of 4uoi by Molmil](/molmil-images/mine/4uoi) | Unexpected structure for the N-terminal domain of Hepatitis C virus envelope glycoprotein E1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GENOME POLYPROTEIN | 著者 | El Omari, K, Iourin, O, Kadlec, J, Harlos, K, Grimes, J.M, Stuart, D.I. | 登録日 | 2014-06-04 | 公開日 | 2014-08-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | Unexpected Structure for the N-Terminal Domain of Hepatitis C Virus Envelope Glycoprotein E1 Acta Crystallogr.,Sect.D, 70, 2014
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7RKH
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![BU of 7rkh by Molmil](/molmil-images/mine/7rkh) | Yeast CTP Synthase (URA8) tetramer bound to ATP/UTP at neutral pH | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ... | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-22 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RMV
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![BU of 7rmv by Molmil](/molmil-images/mine/7rmv) | Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-28 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RMK
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![BU of 7rmk by Molmil](/molmil-images/mine/7rmk) | Yeast CTP Synthase (Ura7) Bundle bound to substrates at low pH | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-27 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RNR
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![BU of 7rnr by Molmil](/molmil-images/mine/7rnr) | Yeast CTP Synthase (Ura8) Bundle Bound to Substrates at Low pH | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ... | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-29 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RNL
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![BU of 7rnl by Molmil](/molmil-images/mine/7rnl) | Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates | 分子名称: | CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-29 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RMF
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![BU of 7rmf by Molmil](/molmil-images/mine/7rmf) | Substrate-bound Ura7 filament at low pH | 分子名称: | CTP synthase | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-27 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RMC
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![BU of 7rmc by Molmil](/molmil-images/mine/7rmc) | Yeast CTP Synthase (Ura7) filament bound to CTP at low pH | 分子名称: | CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-27 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RL5
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![BU of 7rl5 by Molmil](/molmil-images/mine/7rl5) | Yeast CTP Synthase (URA8) filament bound to CTP at low pH | 分子名称: | CTP synthase, CYTIDINE-5'-TRIPHOSPHATE | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-23 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RMO
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![BU of 7rmo by Molmil](/molmil-images/mine/7rmo) | Yeast CTP Synthase (Ura7) Bundle bound to Products at low pH | 分子名称: | CTP synthase, CYTIDINE-5'-TRIPHOSPHATE | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-27 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RL0
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![BU of 7rl0 by Molmil](/molmil-images/mine/7rl0) | Yeast CTP Synthase (URA8) Filament bound to ATP/UTP at low pH | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ... | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-22 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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6ZP7
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![BU of 6zp7 by Molmil](/molmil-images/mine/6zp7) | SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up open conformation) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Martinez, M, Marabini, R, Carazo, J.M. | 登録日 | 2020-07-08 | 公開日 | 2020-07-29 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures. Iucrj, 7, 2020
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6ZOW
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![BU of 6zow by Molmil](/molmil-images/mine/6zow) | SARS-CoV-2 spike in prefusion state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Martinez, M, Marabini, R, Carazo, J.M. | 登録日 | 2020-07-07 | 公開日 | 2020-07-29 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures. Iucrj, 7, 2020
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6ZP5
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![BU of 6zp5 by Molmil](/molmil-images/mine/6zp5) | SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up closed conformation) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Martinez, M, Marabini, R, Carazo, J.M. | 登録日 | 2020-07-08 | 公開日 | 2020-07-29 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures. Iucrj, 7, 2020
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7JZV
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![BU of 7jzv by Molmil](/molmil-images/mine/7jzv) | Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | 分子名称: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | 著者 | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1. Nat.Struct.Mol.Biol., 28, 2021
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6IC4
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6I2D
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![BU of 6i2d by Molmil](/molmil-images/mine/6i2d) | |
6ZTB
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![BU of 6ztb by Molmil](/molmil-images/mine/6ztb) | Crystal Structure of human P-Cadherin EC1_EC2 | 分子名称: | CALCIUM ION, Cadherin-3, SODIUM ION | 著者 | Rondeau, J.M, Lehmann, S. | 登録日 | 2020-07-17 | 公開日 | 2021-05-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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6ZTF
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6ZTR
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![BU of 6ztr by Molmil](/molmil-images/mine/6ztr) | Crystal Structure of the anti-human P-Cadherin Fab CQY684 in complex with human P-Cadherin(108-324) | 分子名称: | CALCIUM ION, CQY684 Fab heavy-chain, CQY684 Fab light-chain, ... | 著者 | Rondeau, J.M, Lehmann, S. | 登録日 | 2020-07-20 | 公開日 | 2021-05-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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8FOZ
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![BU of 8foz by Molmil](/molmil-images/mine/8foz) | Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; filament assembly interface reconstruction | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | O'Neill, A.G, Kollman, J.M. | 登録日 | 2023-01-03 | 公開日 | 2023-04-19 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. J.Biol.Chem., 299, 2023
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