1XIL
 
 | | HYDROGEN BONDING IN HUMAN MANGANESE SUPEROXIDE DISMUTASE CONTAINING 3-FLUOROTYROSINE | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Ayala, I, Perry, J.J, Szczepanski, J, Cabelli, D.E, Tainer, J.A, Vala, M.T, Nick, H.S, Silverman, D.N. | | 登録日 | 2004-09-21 | | 公開日 | 2005-03-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Hydrogen bonding in human manganese superoxide dismutase containing 3-fluorotyrosine
Biophys.J., 89, 2005
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6ZYA
 | | Extended human uromodulin filament core at 3.5 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R. | | 登録日 | 2020-07-31 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism.
Elife, 9, 2020
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3CWL
 | | Crystal structure of alpha-1-antitrypsin, crystal form B | | 分子名称: | Alpha-1-antitrypsin, CHLORIDE ION | | 著者 | Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W. | | 登録日 | 2008-04-22 | | 公開日 | 2008-09-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008
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3CYO
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7NWF
 | | Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with hybrid-type glycan (GalGlcNAcMan5GlcNAc) product | | 分子名称: | Endo-beta-N-acetylglucosaminidase F1, GLYCEROL, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Trastoy, B, Du, J.J, Garcia-Alija, M, Sundberg, E.J, Guerin, M.E. | | 登録日 | 2021-03-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | GH18 endo-beta-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans.
J.Biol.Chem., 297, 2021
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1YXE
 | | Structure and inter-domain interactions of domain II from the blood stage malarial protein, apical membrane antigen 1 | | 分子名称: | apical membrane antigen 1 | | 著者 | Feng, Z.P, Keizer, D.W, Stevenson, R.A, Yao, S, Babon, J.J, Murphy, V.J, Anders, R.F, Norton, R.S. | | 登録日 | 2005-02-21 | | 公開日 | 2005-07-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Inter-domain Interactions of Domain II from the Blood-stage Malarial Protein, Apical Membrane Antigen 1.
J.Mol.Biol., 350, 2005
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1ZLL
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3D4U
 | | Bovine thrombin-activatable fibrinolysis inhibitor (TAFIa) in complex with tick-derived carboxypeptidase inhibitor. | | 分子名称: | ACETATE ION, Carboxypeptidase B2, Carboxypeptidase inhibitor, ... | | 著者 | Sanglas, L, Valnickova, Z, Arolas, J.L, Pallares, I, Guevara, T, Sola, M, Kristensen, T, Enghild, J.J, Aviles, F.X, Gomis-Ruth, F.X. | | 登録日 | 2008-05-15 | | 公開日 | 2008-08-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis.
Mol.Cell, 31, 2008
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1MQN
 | | BHA/LSTc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | | 著者 | ha, y, stevens, d.j, skehel, j.j, wiley, d.c. | | 登録日 | 2002-09-16 | | 公開日 | 2003-08-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus.
Virology, 309, 2003
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4Z3P
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2XBJ
 | | Crystal Structure of Chk2 in complex with an inhibitor | | 分子名称: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, NITRATE ION, ... | | 著者 | Anderson, V.E, Walton, M.I, Eve, P.D, Caldwell, J.J, Pearl, L.H, Oliver, A.W, Collins, I, Garrett, M.D. | | 登録日 | 2010-04-12 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2.
J.Med.Chem., 54, 2011
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1MK2
 | | SMAD3 SBD complex | | 分子名称: | ACETIC ACID, Madh-interacting protein, SMAD 3 | | 著者 | Qin, B.Y, Lam, S.S, Correia, J.J, Lin, K. | | 登録日 | 2002-08-28 | | 公開日 | 2002-10-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control
Genes Dev., 16, 2002
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2XM9
 | | Structure of a small molecule inhibitor with the kinase domain of Chk2 | | 分子名称: | 4-(1H-pyrazol-5-yl)-2-{4-[(3S)-pyrrolidin-3-ylamino]quinazolin-2-yl}phenol, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 | | 著者 | Caldwell, J.J, Welsh, E.J, Matijssen, C, Anderson, V.E, Antoni, L, Boxall, K, Urban, F, Hayes, A, Raynaud, F.I, Rigoreau, L.J, Raynham, T, Aherne, G.W, Pearl, L.H, Oliver, A.W, Garrett, M.D, Collins, I. | | 登録日 | 2010-07-26 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2.
J.Med.Chem., 54, 2011
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1MPZ
 | | NMR solution structure of native Viperidae lebetina obtusa protein | | 分子名称: | Obtustatin | | 著者 | Moreno-Murciano, M.P, Monleon, D, Marcinkiewicz, C, Calvete, J.J, Celda, B. | | 登録日 | 2002-09-13 | | 公開日 | 2003-02-11 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Solution Structure of the Non-RGD Disintegrin Obtustatin
J.Mol.Biol., 329, 2003
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1MQL
 | | BHA of Ukr/63 | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | | 著者 | ha, y, stevens, d.j, skehel, j.j, wiley, d.c. | | 登録日 | 2002-09-16 | | 公開日 | 2003-08-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus.
Virology, 309, 2003
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4ZCV
 | | Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P212121 form | | 分子名称: | CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, GLYCEROL, ... | | 著者 | Harborne, S.P.D, Ruprecht, J.J, Kunji, E.R.S. | | 登録日 | 2015-04-16 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier.
Biochim.Biophys.Acta, 1847, 2015
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3CL0
 | | N1 Neuraminidase H274Y + oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | | 著者 | Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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1YD1
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: magnesium | | 分子名称: | GLYCEROL, MAGNESIUM ION, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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2XKW
 | | LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST PIOGLITAZONE | | 分子名称: | (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Mueller, J.J, Schupp, M, Unger, T, Kintscher, U, Heinemann, U. | | 登録日 | 2010-07-14 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Binding Diversity of Pioglitazone by Peroxisome Proliferator-Activated Receptor-Gamma
To be Published
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1YD0
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: manganese | | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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4ZJC
 | | Structures of the human OX1 orexin receptor bound to selective and dual antagonists | | 分子名称: | OLEIC ACID, [5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]{(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl}methanone, human OX1R fusion protein to P.abysii glycogen synthase | | 著者 | Yin, J, Brautigam, C.A, Shao, Z, Clark, L, Harrell, C.M, Gotter, A.L, Coleman, P.J, Renger, J.J, Rosenbaum, D.M. | | 登録日 | 2015-04-29 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.832 Å) | | 主引用文献 | Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Nat.Struct.Mol.Biol., 23, 2016
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1YD3
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y43F bound to its catalytic divalent cation | | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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2XC1
 | | Full-length Tailspike Protein Mutant Y108W of Bacteriophage P22 | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, ... | | 著者 | Mueller, J.J, Seul, A, Seckler, R, Heinemann, U. | | 登録日 | 2010-04-15 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker
Acta Crystallogr.,Sect.D, 70, 2014
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3CWM
 | | Crystal structure of alpha-1-antitrypsin complexed with citrate | | 分子名称: | Alpha-1-antitrypsin, CITRIC ACID | | 著者 | Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W. | | 登録日 | 2008-04-22 | | 公開日 | 2008-09-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008
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1NIN
 | | PLASTOCYANIN FROM ANABAENA VARIABILIS, NMR, 20 STRUCTURES | | 分子名称: | COPPER (II) ION, PLASTOCYANIN | | 著者 | Badsberg, U, Jorgensen, A.M.M, Gesmar, H, Led, J.J, Hammerstad-Petersen, J.M, Ulstrup, J. | | 登録日 | 1996-03-13 | | 公開日 | 1996-10-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of reduced plastocyanin from the blue-green alga Anabaena variabilis.
Biochemistry, 35, 1996
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