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PDB: 6626 件

4UV4
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Crystal structure of anti-FPR Fpro0165 Fab fragment
分子名称: FPRO0165 FAB
著者Douthwaite, J.A, Sridharan, S, Huntington, C, Marwood, R, Hammersley, J, Hakulinen, J.K, Ek, M, Sjogren, T, Rider, D, Privezentzev, C, Seaman, J.C, Cariuk, P, Knights, V, Young, J, Wilkinson, T, Sleeman, M, Finch, D.K, Lowe, D.C, Vaughan, T.J.
登録日2014-08-04
公開日2014-12-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1.
Mabs, 7, 2015
4UVE
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Discovery of pyrimidine isoxazoles InhA in complex with compound 9
分子名称: 2-(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYLETHANOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], MAGNESIUM ION, ...
著者Read, J.A, Gingell, H, Madhavapeddi, P, Ghorpade, S, Cowan, S.
登録日2014-08-05
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Hitting the Target in More Than One Way: Novel, Direct Inhibitors of Mycobacterium Tuberculosis Enoyl Acp Reductase
To be Published
4UVG
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Discovery of pyrimidine isoxazoles InhA in complex with compound 15
分子名称: 5-[(4,6-dimethylpyrimidin-2-yl)sulfanylmethyl]isoxazole-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], MAGNESIUM ION, ...
著者Read, J.A, Gingell, H, Madhavapeddi, P, Ghorpade, S, Cowan, S.
登録日2014-08-05
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Hitting the Target in More Than One Way: Novel, Direct Inhibitors of Mycobacterium Tuberculosis Enoyl Acp Reductase
To be Published
4UUV
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Structure of the DNA binding ETS domain of human ETV4 in complex with DNA
分子名称: 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', ETS TRANSLOCATION VARIANT 4
著者Newman, J.A, Cooper, C.D.O, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O.
登録日2014-07-31
公開日2014-08-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
4V3J
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Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MONOTREME LACTATING PROTEIN
著者Kumar, A, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R.
登録日2014-10-20
公開日2016-01-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4V00
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Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MONOTREME LACTATING PROTEIN
著者Enjapoori, A.K, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R.
登録日2014-09-10
公開日2015-09-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4V6E
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Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, W, Dunkle, J.A, Cate, J.H.D.
登録日2009-06-28
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.712 Å)
主引用文献Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4UTW
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Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens
分子名称: CHLORIDE ION, N-acetyl-D-glucosamine-6-phosphate, PUTATIVE N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE
著者Pelissier, M.C, Sebban-Kreuzer, C, Guerlesquin, F, Brannigan, J.A, Davies, G.J, Bourne, Y, Vincent, F.
登録日2014-07-23
公開日2014-10-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Characterization of the Clostridium Perfringens N-Acetylmannosamine-6-Phosphate 2-Epimerase Essential for the Sialic Acid Salvage Pathway
J.Biol.Chem., 289, 2014
4V7T
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Crystal structure of the E. coli ribosome bound to chloramphenicol.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-14
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1942 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V97
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Crystal structure of the bacterial ribosome ram mutation G299A.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2012-04-06
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.516 Å)
主引用文献Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4WQC
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Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208N mutant
分子名称: 1,2-ETHANEDIOL, HEME C, SULFATE ION, ...
著者Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
登録日2014-10-21
公開日2015-02-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
4WQ8
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Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - tetrathionate soak
分子名称: HEME C, IODIDE ION, SULFATE ION, ...
著者Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
登録日2014-10-21
公開日2015-02-18
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.3989 Å)
主引用文献Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
4WQ9
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Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - dithionite soak
分子名称: 1,2-ETHANEDIOL, HEME C, HYDROSULFURIC ACID, ...
著者Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
登録日2014-10-21
公開日2015-02-18
最終更新日2021-09-08
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
4WQA
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BU of 4wqa by Molmil
Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - tetrathionate co-crystallization
分子名称: 1,2-ETHANEDIOL, HEME C, IODIDE ION, ...
著者Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
登録日2014-10-21
公開日2015-02-18
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
4WQE
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BU of 4wqe by Molmil
Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208G mutant
分子名称: HEME C, IODIDE ION, SULFATE ION, ...
著者Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
登録日2014-10-21
公開日2015-02-18
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
4WQD
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BU of 4wqd by Molmil
Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208G mutant
分子名称: 1,2-ETHANEDIOL, GUANIDINE, HEME C, ...
著者Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
登録日2014-10-21
公開日2015-02-18
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
4ZN9
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Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Oxabicyclic Heptene Sulfonate (OBHS)
分子名称: Estrogen receptor, Nuclear receptor-interacting peptide, cyclohexa-2,5-dien-1-yl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
著者Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
登録日2015-05-04
公開日2015-09-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.215 Å)
主引用文献Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands.
Chemmedchem, 7, 2012
8IJG
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Crystal structure of alcohol dehydrogenase M5 from Burkholderia gladioli with NADP
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative short-chain dehydrogenases/reductase family protein
著者Han, X, Mei, Z.L, Liu, W.D, Sun, Z.T, Ma, J.A.
登録日2023-02-27
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure of alcohol dehydrogenase from Burkholderia gladioli with NADP
To Be Published
8OET
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SFX structure of the class II photolyase complexed with a thymine dimer
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, DNA (14-mer), Deoxyribodipyrimidine photo-lyase, ...
著者Lane, T.J, Christou, N.-E, Melo, D.V.M, Apostolopoulou, V, Pateras, A, Mashhour, A.R, Galchenkova, M, Gunther, S, Reinke, P, Kremling, V, Oberthuer, D, Henkel, A, Sprenger, J, Scheer, T.E.S, Lange, E, Yefanov, O.N, Middendorf, P, Sellberg, J.A, Schubert, R, Fadini, A, Cirelli, C, Beale, E.V, Johnson, P, Dworkowski, F, Ozerov, D, Bertrand, Q, Wranik, M, Zitter, E.D, Turk, D, Bajt, S, Chapman, H, Bacellar, C.
登録日2023-03-12
公開日2023-11-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Time-resolved crystallography captures light-driven DNA repair.
Science, 382, 2023
8OF5
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Crystal structure of Aurora A 122-403 C290A, N332A, Q335A, C393A bound to ADP
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
著者Miles, J.A, Hammond, K.L.R, Bayliss, R.
登録日2023-03-14
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structure of Aurora A 122-403 C290A, N332A, Q335A, C393A bound to ADP
To Be Published
8OJL
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Human Mitochondrial Lon Y394E Mutant ADP Bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
著者Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
登録日2023-03-24
公開日2024-04-03
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OM7
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Human Mitochondrial Lon Y186E Mutant ADP Bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
著者Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
登録日2023-03-31
公開日2024-04-10
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OKA
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Human Mitochondrial Lon Y394F Mutant ADP Bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
著者Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
登録日2023-03-28
公開日2024-04-10
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8PI2
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Native alpha-1-antitrypsin at 1.5 Angstrom (Cys232Ser)
分子名称: 1,2-ETHANEDIOL, Alpha-1-antitrypsin, DIMETHYL SULFOXIDE, ...
著者Wang, M, Irving, J.A.
登録日2023-06-20
公開日2023-07-05
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural determinants of instability in alpha-1-antitrypsin
To Be Published
8IJ6
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Crystal structure of alcohol dehydrogenase from Burkholderia gladioli with NADP
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative short-chain dehydrogenases/reductase family protein
著者Han, X, Mei, Z.L, Liu, W.D, Sun, Z.T, Ma, J.A.
登録日2023-02-26
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structure of alcohol dehydrogenase from Burkholderia gladioli with NADP
To Be Published

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件を2024-07-17に公開中

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