Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 6626 件
1YK8
DownloadVisualize
BU of 1yk8 by Molmil
Cathepsin K complexed with a cyanamide-based inhibitor
分子名称: Cathepsin K, TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE
著者Barrett, D.G, Deaton, D.N, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Payne, J.A, Shewchuk, L.M, Willard, D.H, Wright, L.L.
登録日2005-01-17
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Acyclic cyanamide-based inhibitors of cathepsin K.
Bioorg.Med.Chem.Lett., 15, 2005
5D5L
DownloadVisualize
BU of 5d5l by Molmil
PreQ1-II riboswitch with an engineered G-U wobble pair bound to Cs+
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, CESIUM ION, MAGNESIUM ION, ...
著者Wedekind, J.E, Liberman, J.A, Salim, M.
登録日2015-08-10
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cesium(I) binding to G-U-wobble base pairs in preQ1 riboswitches with implications for crystallographic phasing
to be published
1YKD
DownloadVisualize
BU of 1ykd by Molmil
Crystal Structure of the Tandem GAF Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand-Binding and Dimerization
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, adenylate cyclase
著者Martinez, S.E, Bruder, S, Schultz, A, Zheng, N, Schultz, J.E, Beavo, J.A, Linder, J.U.
登録日2005-01-17
公開日2005-02-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization
Proc.Natl.Acad.Sci.USA, 102, 2005
4AL4
DownloadVisualize
BU of 4al4 by Molmil
rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)3-oxo-propyl)carbamoylamino)ethoxy)phenyl)methylpropanedioic acid
分子名称: 2-[[4-[2-[[3-[(2-methyl-1,3-benzothiazol-6-yl)amino]-3-oxidanylidene-propyl]carbamoylamino]ethoxy]phenyl]methyl]propanedioic acid, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN
著者Tucker, J.A, Brassington, C, Hassall, G, Ward, R, Tart, J, Davies, G, Hohson, M, Pearson, S.
登録日2012-03-01
公開日2012-03-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
J.Med.Chem., 55, 2012
4AQ3
DownloadVisualize
BU of 4aq3 by Molmil
HUMAN BCL-2 WITH PHENYLACYLSULFONAMIDE INHIBITOR
分子名称: APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1, N,N-dibutyl-4-chloranyl-1-[2-(3,4-dihydro-1H-isoquinolin-2-ylcarbonyl)-4-[(7-iodanylnaphthalen-2-yl)sulfonylcarbamoyl]phenyl]-5-methyl-pyrazole-3-carboxamide
著者Bertrand, J.A, Fasolini, M, Modugno, M.
登録日2012-04-12
公開日2012-06-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a Phenylacylsulfonamide Series of Dual Bcl-2/Bcl-Xl Antagonists.
Bioorg.Med.Chem.Lett., 22, 2012
1XME
DownloadVisualize
BU of 1xme by Molmil
Structure of Recombinant Cytochrome ba3 Oxidase from Thermus thermophilus
分子名称: COPPER (II) ION, Cytochrome c oxidase polypeptide I, Cytochrome c oxidase polypeptide II, ...
著者Hunsicker-Wang, L.M, Pacoma, R.L, Chen, Y, Fee, J.A, Stout, C.D.
登録日2004-10-01
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A novel cryoprotection scheme for enhancing the diffraction of crystals of recombinant cytochrome ba3 oxidase from Thermus thermophilus.
Acta Crystallogr.,Sect.D, 61, 2005
5DID
DownloadVisualize
BU of 5did by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a difluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol
分子名称: (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2
著者Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
登録日2015-08-31
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
1XBX
DownloadVisualize
BU of 1xbx by Molmil
Structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/R139V/T169A mutant with bound D-ribulose 5-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, 5-O-phosphono-L-ribulose, MAGNESIUM ION, ...
著者Wise, E.L, Yew, W.S, Akana, J, Gerlt, J.A, Rayment, I.
登録日2004-08-31
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase
Biochemistry, 44, 2005
1XP3
DownloadVisualize
BU of 1xp3 by Molmil
Crystal Structure of Endonuclease IV (BA4508) from Bacillus anthracis at 2.57A Resolution.
分子名称: SULFATE ION, ZINC ION, endonuclease IV
著者Fogg, M.J, Levdikov, V.M, Blagova, E.V, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
登録日2004-10-08
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Crystal Structure of Endonuclease IV (BA4508) from Bacillus anthracis at 2.57A Resolution.
To be Published
4ANF
DownloadVisualize
BU of 4anf by Molmil
Structure of the ornithine carbamoyltransferase from Mycoplasma penetrans with a P23 Space group
分子名称: ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC
著者Gallego, P, Benach, J, Planell, R, Querol, E, Perez-Pons, J.A, Reverter, D.
登録日2012-03-16
公開日2012-03-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma Penetrans.
Plos One, 7, 2012
1XEA
DownloadVisualize
BU of 1xea by Molmil
Crystal structure of a Gfo/Idh/MocA family oxidoreductase from Vibrio cholerae
分子名称: NICKEL (II) ION, Oxidoreductase, Gfo/Idh/MocA family
著者R Rajashankar, K, Reynes, J.A, Kniewel, R, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2004-09-09
公開日2004-09-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of a Gfo/Idh/MocA family oxidoreductase from Vibrio cholerae
To be Published
1XIL
DownloadVisualize
BU of 1xil by Molmil
HYDROGEN BONDING IN HUMAN MANGANESE SUPEROXIDE DISMUTASE CONTAINING 3-FLUOROTYROSINE
分子名称: MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial
著者Ayala, I, Perry, J.J, Szczepanski, J, Cabelli, D.E, Tainer, J.A, Vala, M.T, Nick, H.S, Silverman, D.N.
登録日2004-09-21
公開日2005-03-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Hydrogen bonding in human manganese superoxide dismutase containing 3-fluorotyrosine
Biophys.J., 89, 2005
4AL6
DownloadVisualize
BU of 4al6 by Molmil
Crystal structure of the S148ACsy4-crRNA complex
分子名称: CRRNA, 5'-R(CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP* CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
5A46
DownloadVisualize
BU of 5a46 by Molmil
FGFR1 in complex with dovitinib
分子名称: 1,2-ETHANEDIOL, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ...
著者Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L.
登録日2015-06-05
公開日2015-08-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
1XR3
DownloadVisualize
BU of 1xr3 by Molmil
Actinorhodin Polyketide Ketoreductase with NADP and the Inhibitor Isoniazid bound
分子名称: 4-(DIAZENYLCARBONYL)PYRIDINE, ACTINORHODIN POLYKETIDE KETOREDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Korman, T.P, Hill, J.A, Vu, T.N, Tsai, S.C.
登録日2004-10-13
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity.
Biochemistry, 43, 2004
1XVR
DownloadVisualize
BU of 1xvr by Molmil
echinomycin (CGTACG)2 complex
分子名称: 2-CARBOXYQUINOXALINE, 5'-D(*CP*GP*TP*AP*CP*G)-3', ECHINOMYCIN, ...
著者Cuesta-Seijo, J.A, Sheldrick, G.M.
登録日2004-10-28
公開日2005-04-12
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of Complexes between Echinomycin and Duplex DNA.
Acta Crystallogr.,Sect.D, 61, 2005
4A3R
DownloadVisualize
BU of 4a3r by Molmil
Crystal structure of Enolase from Bacillus subtilis.
分子名称: CITRIC ACID, ENOLASE, SODIUM ION
著者Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A.S, Harwood, C.R, Lewis, R.J.
登録日2011-10-04
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dissection of the Network of Interactions that Links RNA Processing with Glycolysis in the Bacillus Subtilis Degradosome.
J.Mol.Biol., 416, 2012
1KZX
DownloadVisualize
BU of 1kzx by Molmil
Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T)
分子名称: INTESTINAL FATTY ACID-BINDING PROTEIN (T54)
著者Zhang, F, Luecke, C, Baier, L.J, Sacchettini, J.C, Hamilton, J.A.
登録日2002-02-08
公開日2003-07-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism
Biochemistry, 42, 2003
4A3S
DownloadVisualize
BU of 4a3s by Molmil
Crystal structure of PFK from Bacillus subtilis
分子名称: 6-PHOSPHOFRUCTOKINASE
著者Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A.S, Harwood, C.R, Lewis, R.J.
登録日2011-10-04
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dissection of the Network of Interactions that Links RNA Processing with Glycolysis in the Bacillus Subtilis Degradosome.
J.Mol.Biol., 416, 2012
1XMN
DownloadVisualize
BU of 1xmn by Molmil
Crystal structure of thrombin bound to heparin
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ...
著者Carter, W.J, Cama, E, Huntington, J.A.
登録日2004-10-04
公開日2004-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of thrombin bound to heparin
J.Biol.Chem., 280, 2005
5AA4
DownloadVisualize
BU of 5aa4 by Molmil
Crystal structure of MltF from Pseudomonas aeruginosa in complex with cell-wall tetrapeptide
分子名称: MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F, [6-[[(2~{R})-1-azanyl-1-oxidanylidene-propan-2-yl]amino]-6-oxidanylidene-5-[[(4~{R})-5-oxidanyl-5-oxidanylidene-4-[[(2~{S})-2-[[(2~{R})-2-oxidanylpropanoyl]amino]propanoyl]amino]pentanoyl]amino]hexyl]azanium
著者Dominguez-Gil, T, Acebron, I, Hermoso, J.A.
登録日2015-07-23
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.
Structure, 24, 2016
5DIG
DownloadVisualize
BU of 5dig by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoromethyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol
分子名称: (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2
著者Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
登録日2015-09-01
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
4AMU
DownloadVisualize
BU of 4amu by Molmil
Structure of ornithine carbamoyltransferase from Mycoplasma penetrans with a P321 space group
分子名称: ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC
著者Gallego, P, Benach, J, Planell, R, Querol, E, Perez-Pons, J.A, Reverter, D.
登録日2012-03-13
公開日2012-03-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma Penetrans.
Plos One, 7, 2012
5D55
DownloadVisualize
BU of 5d55 by Molmil
Crystal structure of the E. coli Hda pilus minor tip subunit, HdaB
分子名称: CITRATE ANION, HdaB,HdaA (Adhesin), HUS-associated diffuse adherence, ...
著者Lee, W.-C, Garnett, J.A, Matthews, S.J.
登録日2015-08-10
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and analysis of HdaB: The enteroaggregative Escherichia coli AAF/IV pilus tip protein.
Protein Sci., 25, 2016
5D0J
DownloadVisualize
BU of 5d0j by Molmil
Grb7 SH2 with inhibitor peptide
分子名称: G7-TEdFP peptide, Growth factor receptor-bound protein 7, PHOSPHATE ION
著者Gunzburg, M.J, Watson, G.M, Wilce, J.A, Wilce, M.C.J.
登録日2015-08-03
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon