4CPK
| Crystal structure of PBP2a double clinical mutant N146K-E150K from MRSA | 分子名称: | CADMIUM ION, CHLORIDE ION, Penicillin binding protein 2 prime, ... | 著者 | Otero, L.H, Rojas-Altuve, A, Hermoso, J.A. | 登録日 | 2014-02-07 | 公開日 | 2014-09-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Disruption of Allosteric Response as an Unprecedented Mechanism of Resistance to Antibiotics. J.Am.Chem.Soc., 136, 2014
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1RQ2
| MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH CITRATE | 分子名称: | CITRIC ACID, Cell division protein ftsZ | 著者 | Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W. | 登録日 | 2003-12-04 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches. J.Mol.Biol., 342, 2004
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1CSL
| CRYSTAL STRUCTURE OF THE RRE HIGH AFFINITY SITE | 分子名称: | 5'-R(*AP*AP*CP*GP*GP*GP*CP*GP*CP*AP*GP*AP*A)-3', 5'-R(*UP*CP*UP*GP*AP*CP*GP*GP*UP*AP*CP*GP*UP*UP*U)-3' | 著者 | Ippolito, J.A, Steitz, T.A. | 登録日 | 1999-08-18 | 公開日 | 2000-02-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution. J.Mol.Biol., 295, 2000
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1KYR
| Crystal Structure of a Cu-bound Green Fluorescent Protein Zn Biosensor | 分子名称: | COPPER (II) ION, Green Fluorescent Protein, MAGNESIUM ION | 著者 | Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2002-02-05 | 公開日 | 2002-04-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural chemistry of a green fluorescent protein Zn biosensor. J.Am.Chem.Soc., 124, 2002
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1RTX
| Crystal Structure of Synechocystis Hemoglobin with a Covalent Heme Linkage | 分子名称: | CADMIUM ION, Cyanoglobin, POTASSIUM ION, ... | 著者 | Hoy, J.A, Kundu, S, Trent, J.T, Ramaswamy, S, Hargrove, M.S. | 登録日 | 2003-12-10 | 公開日 | 2004-04-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of synechocystis hemoglobin with a covalent heme linkage. J.Biol.Chem., 279, 2004
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1CVB
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4D2B
| Structure of a ligand free POT family peptide transporter | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, DI-OR TRIPEPTIDE:H+ SYMPORTER, ... | 著者 | Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S. | 登録日 | 2014-05-09 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters. Embo Rep., 15, 2014
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1SO4
| Crystal structure of K64A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate | 分子名称: | 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION | 著者 | Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I. | 登録日 | 2004-03-12 | 公開日 | 2004-06-08 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,) Biochemistry, 43, 2004
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4JBB
| Crystal structure of Glutathione S-transferase A6TBY7(Target EFI-507184) from Klebsiella pneumoniae MGH 78578, GSH complex | 分子名称: | CHLORIDE ION, FORMIC ACID, GLUTATHIONE, ... | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-02-19 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal Structure of Glutathione S-Transferase A6Tby7 (Target Efi-507184) from Klebsiella Pneumoniae To be Published
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1LRN
| Aquifex aeolicus KDO8P synthase H185G mutant in complex with Cadmium | 分子名称: | CADMIUM ION, KDO-8-phosphate synthetase, PHOSPHATE ION | 著者 | Wang, J, Duewel, H.S, Stuckey, J.A, Woodard, R.W, Gatti, D.L. | 登録日 | 2002-05-15 | 公開日 | 2002-11-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Function of His185 in Aquifex aeolicus 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase J.Mol.Biol., 324, 2002
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4JPY
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1SJD
| x-ray structure of o-succinylbenzoate synthase complexed with n-succinyl phenylglycine | 分子名称: | N-SUCCINYL PHENYLGLYCINE, N-acylamino acid racemase | 著者 | Thoden, J.B, Taylor-Ringia, E.A, Garrett, J.B, Gerlt, J.A, Holden, H.M, Rayment, I. | 登録日 | 2004-03-03 | 公開日 | 2004-06-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis Biochemistry, 43, 2004
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4JFZ
| Structure of phosphoserine (pSAb) scaffold bound to pSer peptide | 分子名称: | Fab heavy chain, Fab light chain, PROPANOIC ACID, ... | 著者 | Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A. | 登録日 | 2013-02-28 | 公開日 | 2013-08-28 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Nature-inspired design of motif-specific antibody scaffolds. Nat.Biotechnol., 31, 2013
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3NQE
| Crystal structure of the mutant L123N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | 登録日 | 2010-06-29 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.421 Å) | 主引用文献 | Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50, 2011
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4JUU
| Crystal structure of a putative hydroxyproline epimerase from xanthomonas campestris (TARGET EFI-506516) with bound phosphate and unknown ligand | 分子名称: | CHLORIDE ION, Epimerase, PHOSPHATE ION, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-03-25 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of a putative hydroxyproline epimerase from xanthomonas campestris (TARGET EFI-506516) with bound phosphate and unknown ligand To be Published
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1LDP
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4JXK
| Crystal Structure of Oxidoreductase ROP_24000 (Target EFI-506400) from Rhodococcus opacus B4 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, oxidoreductase | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-03-28 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Oxidoreductase Rop_24000 (Target EFI-506400) from Rhodococcus Opacus To be Published
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4JXY
| CRYSTAL STRUCTURE OF POLYPRENYL SYNTHASE PATL_3739 (TARGET EFI-509195) FROM Pseudoalteromonas atlantica | 分子名称: | GLUTARIC ACID, PHOSPHATE ION, Trans-hexaprenyltranstransferase | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-03-28 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | CRYSTAL STRUCTURE OF ISOPRENOID SYNTHASE PATL_3739 FROM Pseudoalteromonas atlantica To be Published
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3NQ7
| Crystal structure of the mutant F71A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | 登録日 | 2010-06-29 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.443 Å) | 主引用文献 | Crystal structure of the mutant F71A of orotidine 5'-monophosphate
decarboxylase from Methanobacterium thermoautotrophicum complexed with
inhibitor BMP To be Published
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1L99
| PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES | 分子名称: | BETA-MERCAPTOETHANOL, T4 LYSOZYME | 著者 | Pjura, P, Mcintosh, L.P, Wozniak, J.A, Matthews, B.W. | 登録日 | 1992-07-13 | 公開日 | 1993-10-31 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties. Proteins, 15, 1993
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3NXW
| Crystal structure of Staphylococcal nuclease variant Delta+PHS L125A at cryogenic temperature | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | 著者 | Caro, J.A, Schlessman, J.L, Garcia-Moreno, E.B, Heroux, A. | 登録日 | 2010-07-14 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Cavities determine the pressure unfolding of proteins. Proc.Natl.Acad.Sci.USA, 109, 2012
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1SJ4
| Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution | 分子名称: | precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A | 著者 | Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A. | 登録日 | 2004-03-02 | 公開日 | 2004-05-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A Conformational Switch controls hepatitis delta virus ribozyme
catalysis Nature, 429, 2004
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1SJB
| X-ray structure of o-succinylbenzoate synthase complexed with o-succinylbenzoic acid | 分子名称: | 2-SUCCINYLBENZOATE, MAGNESIUM ION, N-acylamino acid racemase | 著者 | Thoden, J.B, Taylor-Ringia, E.A, Garrett, J.B, Gerlt, J.A, Holden, H.M, Rayment, I. | 登録日 | 2004-03-03 | 公開日 | 2004-06-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis Biochemistry, 43, 2004
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1CEQ
| CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE. | 分子名称: | PROTEIN (L-LACTATE DEHYDROGENASE) | 著者 | Read, J.A, Wilkinson, K.W, Tranter, R, Sessions, R.B, Brady, R.L. | 登録日 | 1999-03-10 | 公開日 | 1999-03-19 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase. J.Biol.Chem., 274, 1999
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1SKL
| Structure of the antimicrobial hexapeptide cyc-(RRNalNalRF) bound to DPC micelles | 分子名称: | cyclic hexapeptide RR(NAL)(NAL)RF | 著者 | Appelt, C, Soderhall, J.A, Bienert, M, Dathe, M, Schmieder, P. | 登録日 | 2004-03-05 | 公開日 | 2005-03-15 | 最終更新日 | 2012-12-12 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the antimicrobial, cationic hexapeptide cyclo(RRWWRF) and its analogues in solution and bound to detergent micelles. Chembiochem, 6, 2005
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