7UJK
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![BU of 7ujk by Molmil](/molmil-images/mine/7ujk) | Integrin alaphIIBbeta3 complex with lamifiban | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.43265581 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UDG
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![BU of 7udg by Molmil](/molmil-images/mine/7udg) | Integrin alaphIIBbeta3 complex with lotrafiban | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-19 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.800069 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UJE
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![BU of 7uje by Molmil](/molmil-images/mine/7uje) | Integrin alaphIIBbeta3 complex with UR2922 in Mn2+ | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.499968 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UE0
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![BU of 7ue0 by Molmil](/molmil-images/mine/7ue0) | Integrin alaphIIBbeta3 complex with fradafiban | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-20 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.741962 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UKP
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![BU of 7ukp by Molmil](/molmil-images/mine/7ukp) | Integrin alaphIIBbeta3 complex with a gantofiban analog | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-04-01 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.80112982 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UBR
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![BU of 7ubr by Molmil](/molmil-images/mine/7ubr) | Integrin alaphIIBbeta3 complex with GR144053 | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-15 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.04992747 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7ZX4
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![BU of 7zx4 by Molmil](/molmil-images/mine/7zx4) | Clathrin N-terminal domain in complex with a HURP phospho-peptide | Descriptor: | CHLORIDE ION, Clathrin heavy chain 1, Disks large-associated protein 5, ... | Authors: | Kliche, J, Badgujar, D, Dobritzsch, D, Ivarsson, Y. | Deposit date: | 2022-05-20 | Release date: | 2023-03-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions. Mol.Syst.Biol., 19, 2023
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7UH8
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![BU of 7uh8 by Molmil](/molmil-images/mine/7uh8) | Integrin alaphIIBbeta3 complex with roxifiban (Mn/Ca) | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-25 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.750024 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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6SV3
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![BU of 6sv3 by Molmil](/molmil-images/mine/6sv3) | Structure of coproheme-LmCpfC | Descriptor: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Ferrochelatase, GLYCEROL | Authors: | Hofbauer, S, Helm, J, Djinovic-Carugo, K, Furtmueller, P.G. | Deposit date: | 2019-09-17 | Release date: | 2019-12-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.64000869 Å) | Cite: | Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase. Febs J., 287, 2020
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7NSB
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![BU of 7nsb by Molmil](/molmil-images/mine/7nsb) | Supramolecular assembly module of yeast Chelator-GID SR4 E3 ubiquitin ligase | Descriptor: | Glucose-induced degradation protein 7, Glucose-induced degradation protein 8, Vacuolar import and degradation protein 30 | Authors: | Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2021-03-05 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme. Mol.Cell, 81, 2021
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2C1C
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![BU of 2c1c by Molmil](/molmil-images/mine/2c1c) | Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors | Descriptor: | CARBOXYPEPTIDASE B, YTTRIUM ION, ZINC ION | Authors: | Bayes, A, Comellas-Bigler, M, Rodriguez de la Vega, M, Maskos, K, Bode, W, Aviles, F.X, Jongsma, M.A, Beekwilder, J, Vendrell, J. | Deposit date: | 2005-09-12 | Release date: | 2005-10-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of the Resistance of an Insect Carboxypeptidase to Plant Protease Inhibitors. Proc.Natl.Acad.Sci.USA, 102, 2005
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7NS3
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![BU of 7ns3 by Molmil](/molmil-images/mine/7ns3) | Substrate receptor scaffolding module of yeast Chelator-GID SR4 E3 ubiquitin ligase bound to Fbp1 substrate | Descriptor: | BJ4_G0018240.mRNA.1.CDS.1, Fructose-bisphosphatase, Glucose-induced degradation protein 8, ... | Authors: | Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A. | Deposit date: | 2021-03-05 | Release date: | 2021-05-05 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme. Mol.Cell, 81, 2021
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6PAA
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![BU of 6paa by Molmil](/molmil-images/mine/6paa) | |
6B5Q
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![BU of 6b5q by Molmil](/molmil-images/mine/6b5q) | DCN1 bound to 38 | Descriptor: | DCN1-like protein 1, Peptidomimetic Inhibitors DI-591, TRIETHYLENE GLYCOL | Authors: | Stuckey, J. | Deposit date: | 2017-09-29 | Release date: | 2018-02-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction. J. Med. Chem., 61, 2018
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1RGF
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![BU of 1rgf by Molmil](/molmil-images/mine/1rgf) | HYDROLASE, GUANYLORIBONUCLEASE | Descriptor: | RIBONUCLEASE, SULFATE ION | Authors: | Sevcik, J, Dauter, Z, Lamzin, V.S, Wilson, K.S. | Deposit date: | 1995-06-05 | Release date: | 1996-10-14 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Ribonuclease from Streptomyces aureofaciens at atomic resolution. Acta Crystallogr.,Sect.D, 52, 1996
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8I6O
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![BU of 8i6o by Molmil](/molmil-images/mine/8i6o) | |
8I6R
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![BU of 8i6r by Molmil](/molmil-images/mine/8i6r) | Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | Authors: | Xu, X, Li, J, Luo, M. | Deposit date: | 2023-01-29 | Release date: | 2023-06-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site. Proc.Natl.Acad.Sci.USA, 120, 2023
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8I6S
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![BU of 8i6s by Molmil](/molmil-images/mine/8i6s) | Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | Authors: | Xu, X, Li, J, Luo, M. | Deposit date: | 2023-01-29 | Release date: | 2023-06-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site. Proc.Natl.Acad.Sci.USA, 120, 2023
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4L91
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![BU of 4l91 by Molmil](/molmil-images/mine/4l91) | Crystal structure of Human Hsp90 with X29 | Descriptor: | 4-(6-bromo[1,2,4]triazolo[4,3-a]pyridin-3-yl)-6-chlorobenzene-1,3-diol, Heat shock protein HSP 90-alpha | Authors: | Li, J, Ren, J, Yang, M, Xiong, B, He, J. | Deposit date: | 2013-06-18 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization Bioorg.Med.Chem.Lett., 24, 2014
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1R4Y
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![BU of 1r4y by Molmil](/molmil-images/mine/1r4y) | SOLUTION STRUCTURE OF THE DELETION MUTANT DELTA(7-22) OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN | Descriptor: | Ribonuclease alpha-sarcin | Authors: | Garcia-Mayoral, M.F, Garcia-Ortega, L, Lillo, M.P, Santoro, J, Martinez Del Pozo, A, Gavilanes, J.G, Rico, M, Bruix, M. | Deposit date: | 2003-10-09 | Release date: | 2004-04-06 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | NMR structure of the noncytotoxic {alpha}-sarcin mutant {Delta}(7-22): The importance of the native conformation of peripheral loops for activity. Protein Sci., 13, 2004
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7ZKE
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![BU of 7zke by Molmil](/molmil-images/mine/7zke) | Mot1:TBP:DNA - pre-hydrolysis state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (36-MER), ... | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | Deposit date: | 2022-04-12 | Release date: | 2023-04-26 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
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6PH4
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![BU of 6ph4 by Molmil](/molmil-images/mine/6ph4) | Full length LOV-PAS-HK construct from the LOV-HK sensory protein from Brucella abortus (light-adapted, construct 15-489) | Descriptor: | Blue-light-activated histidine kinase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | Authors: | Rinaldi, J, Otero, L.H, Fernandez, I, Goldbaum, F.A, Shin, H, Yang, X, Klinke, S. | Deposit date: | 2019-06-25 | Release date: | 2020-12-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
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6VN7
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![BU of 6vn7 by Molmil](/molmil-images/mine/6vn7) | Cryo-EM structure of an activated VIP1 receptor-G protein complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Duan, J, Shen, D.-D, Zhou, X.E, Liu, Q.-F, Zhuang, Y.-W, Zhang, H.-B, Xu, P.-Y, Ma, S.-S, He, X.-H, Melcher, K, Zhang, Y, Xu, H.E, Yi, J. | Deposit date: | 2020-01-29 | Release date: | 2020-09-02 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy. Nat Commun, 11, 2020
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6SHX
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![BU of 6shx by Molmil](/molmil-images/mine/6shx) | DNA mismatch repair proteins MLH1 and MLH3 | Descriptor: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | Authors: | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | Deposit date: | 2019-08-08 | Release date: | 2021-05-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SNS
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![BU of 6sns by Molmil](/molmil-images/mine/6sns) | DNA mismatch repair proteins MLH1 and MLH3 | Descriptor: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | Authors: | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | Deposit date: | 2019-08-27 | Release date: | 2021-05-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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