4YMT
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![BU of 4ymt by Molmil](/molmil-images/mine/4ymt) | Crystal structure of an amino acid ABC transporter complex with arginines | Descriptor: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | Authors: | Ge, J, Yu, J, Yang, M. | Deposit date: | 2015-03-07 | Release date: | 2015-04-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.599 Å) | Cite: | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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8RNT
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![BU of 8rnt by Molmil](/molmil-images/mine/8rnt) | STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH ZINC(II) AT 1.8 ANGSTROMS RESOLUTION: A ZN2+.6H2O.CARBOXYLATE CLATHRATE | Descriptor: | RIBONUCLEASE T1, ZINC ION | Authors: | Ding, J, Choe, H.-W, Granzin, J, Saenger, W. | Deposit date: | 1991-09-23 | Release date: | 1993-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of ribonuclease T1 complexed with zinc(II) at 1.8 A resolution: a Zn2+.6H2O.carboxylate clathrate. Acta Crystallogr.,Sect.B, 48, 1992
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6W9U
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![BU of 6w9u by Molmil](/molmil-images/mine/6w9u) | Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H-Ac-6-FP | Descriptor: | 1-[[6-(1-$l^{1}-oxidanylethyl)-4-$l^{3}-oxidanylidene-2,3,6,8~{a}-tetrahydropteridin-2-yl]-$l^{2}-azanyl]ethanone, Beta-2-microglobulin, CHLORIDE ION, ... | Authors: | Awad, W, Rossjohn, J. | Deposit date: | 2020-03-23 | Release date: | 2020-08-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1 . Sci Immunol, 5, 2020
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6R5H
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![BU of 6r5h by Molmil](/molmil-images/mine/6r5h) | Major aspartyl peptidase 1 from C. neoformans | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | Authors: | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | Deposit date: | 2019-03-25 | Release date: | 2021-04-07 | Last modified: | 2021-06-09 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery. J.Med.Chem., 64, 2021
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6R6A
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![BU of 6r6a by Molmil](/molmil-images/mine/6r6a) | Major aspartyl peptidase 1 from C. neoformans | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Endopeptidase, ... | Authors: | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | Deposit date: | 2019-03-26 | Release date: | 2021-04-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery. J.Med.Chem., 64, 2021
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5XZR
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![BU of 5xzr by Molmil](/molmil-images/mine/5xzr) | The atomic structure of SHP2 E76A mutant in complex with allosteric inhibitor 9b | Descriptor: | 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Li, D, Xie, J, Zhu, J, Liu, C. | Deposit date: | 2017-07-13 | Release date: | 2017-12-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment. J. Med. Chem., 60, 2017
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4RL1
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![BU of 4rl1 by Molmil](/molmil-images/mine/4rl1) | |
1ZSR
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![BU of 1zsr by Molmil](/molmil-images/mine/1zsr) | Crystal structure of wild type HIV-1 protease (BRU isolate) with a hydroxyethylamine peptidomimetic inhibitor BOC-PHE-PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2 | Descriptor: | N-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-L-phenylalanyl-L-alpha-glutamyl-L-phenylalaninamide, PROTEASE RETROPEPSIN | Authors: | Skalova, T, Dohnalek, J, Duskova, J, Petrokova, H, Hasek, J. | Deposit date: | 2005-05-24 | Release date: | 2006-04-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution. Acta Crystallogr.,Sect.D, 62, 2006
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8QRN
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![BU of 8qrn by Molmil](/molmil-images/mine/8qrn) | mt-SSU in GTPBP8 knock-out cells, state 4 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | Deposit date: | 2023-10-09 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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8QRM
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![BU of 8qrm by Molmil](/molmil-images/mine/8qrm) | mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | Deposit date: | 2023-10-09 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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8BBN
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![BU of 8bbn by Molmil](/molmil-images/mine/8bbn) | SARS-CoV-2 Delta-RBD complexed with BA.2-10 and EY6A Fabs | Descriptor: | BA.2-10 heavy chain, BA.2-10 light chain, EY6A Heavy chain, ... | Authors: | Zhou, D, Ren, J, Stuart, D.I. | Deposit date: | 2022-10-14 | Release date: | 2023-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.58 Å) | Cite: | Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Rep, 42, 2023
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8BCZ
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![BU of 8bcz by Molmil](/molmil-images/mine/8bcz) | SARS-CoV-2 Delta-RBD complexed with Fabs BA.2-36, BA.2-23, EY6A and COVOX-45 | Descriptor: | BA.2-23 heavy chain, BA.2-23 light chain, BA.2-36 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2022-10-17 | Release date: | 2023-03-22 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Rep, 42, 2023
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8SJV
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![BU of 8sjv by Molmil](/molmil-images/mine/8sjv) | [4T24] Self-assembling left-handed tensegrity triangle with 24 interjunction base pairs and R3 symmetry | Descriptor: | DNA (5'-D(P*CP*TP*TP*GP*TP*AP*GP*TP*CP*TP*CP*AP*CP*CP*AP*CP*TP*GP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*GP*AP*AP*CP*AP*CP*TP*CP*CP*TP*GP*AP*GP*AP*CP*TP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*AP*CP*AP*TP*CP*AP*CP*AP*GP*TP*GP*GP*AP*CP*TP*AP*CP*AP*AP*G)-3'), ... | Authors: | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (8.59 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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4Z7U
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![BU of 4z7u by Molmil](/molmil-images/mine/4z7u) | S13 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1, ... | Authors: | Petersen, J, Rossjohn, J, Reid, H.H, Koning, F. | Deposit date: | 2015-04-08 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Determinants of Gliadin-Specific T Cell Selection in Celiac Disease. J Immunol., 194, 2015
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7MY0
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![BU of 7my0 by Molmil](/molmil-images/mine/7my0) | Sy-CrtE IPP structure | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Geranylgeranyl pyrophosphate synthase, ... | Authors: | Peat, T.S, Newman, J. | Deposit date: | 2021-05-19 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
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8SJR
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![BU of 8sjr by Molmil](/molmil-images/mine/8sjr) | [3T17] Self-assembling right-handed tensegrity triangle with 17 interjunction base pairs and R3 symmetry | Descriptor: | DNA (5'-D(*CP*AP*GP*CP*AP*GP*CP*CP*TP*GP*AP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*TP*AP*TP*TP*CP*AP*CP*CP*AP*CP*GP*AP*T)-3'), ... | Authors: | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (5.25 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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8SJM
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![BU of 8sjm by Molmil](/molmil-images/mine/8sjm) | [3T12] Self-assembling left-handed tensegrity triangle with 12 interjunction base pairs and R3 symmetry | Descriptor: | DNA (5'-D(*CP*AP*GP*CP*AP*TP*CP*GP*CP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*CP*GP*CP*AP*TP*GP*TP*GP*GP*CP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*AP*TP*GP*CP*GP*AP*G)-3'), ... | Authors: | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (8.08 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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7N9J
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![BU of 7n9j by Molmil](/molmil-images/mine/7n9j) | Crystal structure of H2DB in complex with HSF2 melanoma neoantigen | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | Deposit date: | 2021-06-18 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure of the complex between H2DB and melanoma HSF2 neoantigen YGFRNVVHI To be Published
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8SJN
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![BU of 8sjn by Molmil](/molmil-images/mine/8sjn) | [3T13] Self-assembling left-handed tensegrity triangle with 13 interjunction base pairs and R3 symmetry | Descriptor: | DNA (5'-D(*CP*AP*GP*CP*AP*TP*CP*GP*CP*CP*TP*GP*AP*CP*TP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*CP*GP*CP*TP*GP*TP*GP*GP*CP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*GP*AP*G)-3'), ... | Authors: | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (7.3 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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7NA5
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![BU of 7na5 by Molmil](/molmil-images/mine/7na5) | Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen | Descriptor: | 47BE7 TCR alpha chain, 47BE7 TCR beta chain, Beta-2-microglobulin, ... | Authors: | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | Deposit date: | 2021-06-19 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the TCR-H2DB ternary complex with melanoma HSF2 neoantigen YGFRNVVHI To be Published
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8SJS
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![BU of 8sjs by Molmil](/molmil-images/mine/8sjs) | [3T18] Self-assembling right-handed tensegrity triangle with 18 interjunction base pairs and P63 symmetry | Descriptor: | DNA (5'-D(*CP*AP*GP*AP*GP*CP*CP*TP*GP*AP*CP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*TP*C)-3'), DNA (5'-D(P*TP*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*G)-3'), ... | Authors: | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (6.31 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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4Z7W
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![BU of 4z7w by Molmil](/molmil-images/mine/4z7w) | T316 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQ8-glia-alpha1, MHC class II HLA-DQ-alpha chain, ... | Authors: | Petersen, J, Rossjohn, J, Reid, H.H, Koning, F. | Deposit date: | 2015-04-08 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Determinants of Gliadin-Specific T Cell Selection in Celiac Disease. J Immunol., 194, 2015
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8SJW
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![BU of 8sjw by Molmil](/molmil-images/mine/8sjw) | [4T28] Self-assembling right-handed tensegrity triangle with 28 interjunction base pairs and R3 symmetry | Descriptor: | DNA (28-MER), DNA (5'-D(*GP*AP*AP*CP*TP*GP*CP*CP*TP*GP*AP*AP*TP*TP*AP*CP*TP*GP*AP*CP*CP*G)-3'), DNA (5'-D(*TP*CP*AP*TP*CP*AP*GP*TP*GP*GP*CP*AP*GP*T)-3'), ... | Authors: | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (7.64 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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8SJQ
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![BU of 8sjq by Molmil](/molmil-images/mine/8sjq) | [3T16] Self-assembling right-handed tensegrity triangle with 16 interjunction base pairs and R3 symmetry | Descriptor: | DNA (5'-D(*CP*AP*GP*CP*AP*TP*GP*CP*CP*TP*GP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*AP*TP*GP*C)-3'), DNA (5'-D(P*TP*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*G)-3'), ... | Authors: | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (6.19 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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8SJP
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![BU of 8sjp by Molmil](/molmil-images/mine/8sjp) | [3T15] Self-assembling DNA motif with 15 base pairs between junctions and P32 symmetry | Descriptor: | DNA (5'-D(*CP*AP*GP*CP*TP*GP*AP*CP*CP*TP*GP*AP*CP*TP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*CP*CP*TP*GP*TP*GP*GP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*CP*GP*AP*TP*GP*GP*AP*CP*AP*GP*GP*GP*G)-3'), ... | Authors: | Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (5.22 Å) | Cite: | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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