8YCM
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![BU of 8ycm by Molmil](/molmil-images/mine/8ycm) | Monomeric Human STK19 | Descriptor: | Isoform 4 of Inactive serine/threonine-protein kinase 19, SULFATE ION | Authors: | Li, J, Ma, X, Dong, Z. | Deposit date: | 2024-02-18 | Release date: | 2024-03-06 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Mutations found in cancer patients compromise DNA binding of the winged helix protein STK19. Sci Rep, 14, 2024
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1RU1
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![BU of 1ru1 by Molmil](/molmil-images/mine/1ru1) | CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.40 ANGSTROM RESOLUTION (MONOCLINIC FORM) | Descriptor: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION, ... | Authors: | Blaszczyk, J, Ji, X. | Deposit date: | 2003-12-10 | Release date: | 2004-02-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase. Biochemistry, 43, 2004
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4X8O
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![BU of 4x8o by Molmil](/molmil-images/mine/4x8o) | Crystal structure of E. coli Adenylate kinase Y171W mutant in complex with inhibitor Ap5a | Descriptor: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... | Authors: | Sauer-Eriksson, A.E, Kovermann, M, Aden, J, Grundstrom, C, Wolf-Watz, M, Sauer, U.H. | Deposit date: | 2014-12-10 | Release date: | 2015-07-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for catalytically restrictive dynamics of a high-energy enzyme state. Nat Commun, 6, 2015
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7XKZ
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![BU of 7xkz by Molmil](/molmil-images/mine/7xkz) | Solution structure of subunit epsilon of the Mycobacterium abscessus F-ATP synthase | Descriptor: | ATP synthase epsilon chain | Authors: | Shin, J, Grueber, G, Harikishore, A, Wong, C.F, Prya, R, Dick, T. | Deposit date: | 2022-04-20 | Release date: | 2023-03-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Atomic solution structure of Mycobacterium abscessus F-ATP synthase subunit epsilon and identification of Ep1MabF1 as a targeted inhibitor. Febs J., 289, 2022
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3V4V
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![BU of 3v4v by Molmil](/molmil-images/mine/3v4v) | crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yu, Y, Zhu, J, Springer, T.A. | Deposit date: | 2011-12-15 | Release date: | 2012-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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8XPX
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![BU of 8xpx by Molmil](/molmil-images/mine/8xpx) | The Crystal Structure of PARP12 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Shen, Z. | Deposit date: | 2024-01-04 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Crystal Structure of PARP12 from Biortus. To Be Published
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1LQL
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![BU of 1lql by Molmil](/molmil-images/mine/1lql) | Crystal structure of OsmC like protein from Mycoplasma pneumoniae | Descriptor: | osmotical inducible protein C like family | Authors: | Choi, I.-G, Shin, D.H, Brandsen, J, Jancarik, J, Kim, R, Yokota, H, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2002-05-10 | Release date: | 2003-08-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of a stress inducible protein from Mycoplasma pneumoniae at 2.85 A resolution J.STRUCT.FUNCT.GENOM., 4, 2003
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6RQ7
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![BU of 6rq7 by Molmil](/molmil-images/mine/6rq7) | Gadolinium MRI contrast compound binding in human plasma glycoprotein afamin - resurrection of highly anisotropic data | Descriptor: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rupp, B, Bowler, M.W, Naschberger, A, Juyoux, P, vonVelsen, J. | Deposit date: | 2019-05-15 | Release date: | 2019-07-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Controlled dehydration, structural flexibility and gadolinium MRI contrast compound binding in the human plasma glycoprotein afamin. Acta Crystallogr D Struct Biol, 75, 2019
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6RTU
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![BU of 6rtu by Molmil](/molmil-images/mine/6rtu) | Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus complexed with alpha-aminoadipic acid | Descriptor: | 2-AMINOHEXANEDIOIC ACID, ACETATE ION, GLYCEROL, ... | Authors: | Hasse, D, Huelsemann, J, Carlsson, G, Andersson, I. | Deposit date: | 2019-05-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus. Acta Crystallogr D Struct Biol, 75, 2019
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4WQN
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![BU of 4wqn by Molmil](/molmil-images/mine/4wqn) | Crystal structure of N6-methyladenosine RNA reader YTHDF2 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, YTH domain-containing family protein 2 | Authors: | Zhu, T, Roundtree, I.A, Wang, P, Wang, X, Wang, L, Sun, C, Tian, Y, Li, J, He, C, Xu, Y. | Deposit date: | 2014-10-22 | Release date: | 2014-11-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.121 Å) | Cite: | Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine. Cell Res., 24, 2014
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8YZN
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![BU of 8yzn by Molmil](/molmil-images/mine/8yzn) | |
3TRK
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![BU of 3trk by Molmil](/molmil-images/mine/3trk) | Structure of the Chikungunya virus nsP2 protease | Descriptor: | Nonstructural polyprotein, SODIUM ION | Authors: | Cheung, J, Franklin, M, Mancia, F, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | Deposit date: | 2011-09-09 | Release date: | 2011-09-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Structure of the Chikungunya virus nsP2 protease To be Published
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4PGA
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![BU of 4pga by Molmil](/molmil-images/mine/4pga) | GLUTAMINASE-ASPARAGINASE FROM PSEUDOMONAS 7A | Descriptor: | AMMONIUM ION, GLUTAMINASE-ASPARAGINASE, SULFATE ION | Authors: | Jakob, C.G, Lewinski, K, Lacount, M.W, Roberts, J, Lebioda, L. | Deposit date: | 1997-01-14 | Release date: | 1997-07-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Ion binding induces closed conformation in Pseudomonas 7A glutaminase-asparaginase (PGA): crystal structure of the PGA-SO4(2-)-NH4+ complex at 1.7 A resolution. Biochemistry, 36, 1997
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6RRM
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![BU of 6rrm by Molmil](/molmil-images/mine/6rrm) | Crystal structure of LdtMt2 from Mycobacterium tuberculosis bound to Ebselen | Descriptor: | 1,2-ETHANEDIOL, AMMONIUM ION, GLYCEROL, ... | Authors: | Brem, J, Lohans, C, Schofield, C. | Deposit date: | 2019-05-20 | Release date: | 2019-08-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Targeting the Mycobacterium tuberculosis transpeptidase LdtMt2with cysteine-reactive inhibitors including ebselen. Chem.Commun.(Camb.), 55, 2019
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9B4H
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![BU of 9b4h by Molmil](/molmil-images/mine/9b4h) | Chlamydomonas reinhardtii mastigoneme filament | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain-containing protein, Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein, ... | Authors: | Dai, J, Ma, M, Zhang, R, Brown, A. | Deposit date: | 2024-03-20 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices. Cell, 2024
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4H52
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![BU of 4h52 by Molmil](/molmil-images/mine/4h52) | Wild-type influenza N2 neuraminidase covalent complex with 3-fluoro-Neu5Ac | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CALCIUM ION, ... | Authors: | Vavricka, C.J, Liu, Y, Kiyota, H, Sriwilaijaroen, N, Qi, J, Tanaka, K, Wu, Y, Li, Q, Li, Y, Yan, J, Suzuki, Y, Gao, G.F. | Deposit date: | 2012-09-18 | Release date: | 2013-02-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors Nat Commun, 4, 2013
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2C8H
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![BU of 2c8h by Molmil](/molmil-images/mine/2c8h) | Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (NAD-bound state, crystal form I) | Descriptor: | MONO-ADP-RIBOSYLTRANSFERASE C3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | Authors: | Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A. | Deposit date: | 2005-12-03 | Release date: | 2007-02-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Properties of Wild-Type and Two Artt Motif Mutants Clostridium Botulinum C3 Exoenzyme Isoform 1 in Different Substrate Complexed States and Crystal Forms. To be Published
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4ZC0
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![BU of 4zc0 by Molmil](/molmil-images/mine/4zc0) | Structure of a dodecameric bacterial helicase | Descriptor: | HEXATANTALUM DODECABROMIDE, Replicative DNA helicase | Authors: | Bazin, A, Cherrier, M.V, Gutsche, I, Timmins, J, Terradot, L. | Deposit date: | 2015-04-15 | Release date: | 2015-10-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (6.7 Å) | Cite: | Structure and primase-mediated activation of a bacterial dodecameric replicative helicase. Nucleic Acids Res., 43, 2015
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4ZQY
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![BU of 4zqy by Molmil](/molmil-images/mine/4zqy) | |
1RNE
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![BU of 1rne by Molmil](/molmil-images/mine/1rne) | |
9B7F
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![BU of 9b7f by Molmil](/molmil-images/mine/9b7f) | S_SAD structure of HEWL using lossless default compression | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | Authors: | Jakoncic, J, Bernstein, H.J, Soares, A.S, Horvat, K. | Deposit date: | 2024-03-27 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments To Be Published
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4Z1K
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![BU of 4z1k by Molmil](/molmil-images/mine/4z1k) | Carbonic anhydrase inhibitors: Design and synthesis of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hCA VII, hCA IX, and hCA XIV) | Descriptor: | 4-[(6,7-dihydroxy-3,4-dihydroisoquinolin-2(1H)-yl)carbonyl]benzenesulfonamide, Carbonic anhydrase 2, ZINC ION | Authors: | Brynda, J, Pospisilova, K, Rezacova, P, Pachl, P. | Deposit date: | 2015-03-27 | Release date: | 2015-08-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. Eur.J.Med.Chem., 102, 2015
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1R43
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![BU of 1r43 by Molmil](/molmil-images/mine/1r43) | Crystal structure of beta-alanine synthase from Saccharomyces kluyveri (selenomethionine substituted protein) | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-AMINO ISOBUTYRATE, ... | Authors: | Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D. | Deposit date: | 2003-10-03 | Release date: | 2003-11-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases J.Biol.Chem., 278
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4Z1R
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![BU of 4z1r by Molmil](/molmil-images/mine/4z1r) | Crystal structure of collagen-like peptide at 1.27 Angstrom resolution | Descriptor: | Collagen-like peptide | Authors: | Plonska-Brzezinska, M.E, Czyrko, J, Brus, D.M, Imierska, M, Brzezinski, K. | Deposit date: | 2015-03-27 | Release date: | 2015-11-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Triple helical collagen-like peptide interactions with selected polyphenolic compounds. Rsc Adv, 5, 2015
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6T35
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![BU of 6t35 by Molmil](/molmil-images/mine/6t35) | Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101) | Descriptor: | Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Lang, P.A, Leissing, T.M, Schofield, C.J, Brem, J. | Deposit date: | 2019-10-10 | Release date: | 2020-11-18 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Studies on enmetazobactam clarify mechanisms of widely used beta-lactamase inhibitors. Proc.Natl.Acad.Sci.USA, 119, 2022
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