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PDB: 42507 件

1GF9
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CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
分子名称: LYSOZYME, SODIUM ION
著者Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
登録日2000-12-04
公開日2000-12-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
1GFJ
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CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
分子名称: LYSOZYME, SODIUM ION
著者Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
登録日2000-12-04
公開日2000-12-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
7ZRA
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Crystal structure of E.coli LexA in complex with nanobody NbSOS1(Nb14497)
分子名称: 1,2-ETHANEDIOL, LexA repressor, Nanobody NbSOS1 (Nb14497)
著者Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L.
登録日2022-05-04
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway.
Structure, 30, 2022
8KG9
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Yeast replisome in state III
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.52 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
5JAG
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LeuT T354H mutant in the outward-oriented, Na+-free Return State
分子名称: Transporter, octyl beta-D-glucopyranoside
著者Malinauskaite, L, Sahin, C, Said, S, Grouleff, J, Shahsavar, A, Bjerregaard, H, Noer, P, Severinsen, K, Boesen, T, Schiott, B, Sinning, S, Nissen, P.
登録日2016-04-12
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.
Nat Commun, 7, 2016
7K3M
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Crystal Structure of the Beta Lactamase Class D from Chitinophaga pinensis by Serial Crystallography
分子名称: Beta-lactamase
著者Kim, Y, Sherrell, D.A, Johnson, J, Lavens, A, Maltseva, N, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-11
公開日2020-09-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Beta Lactamase Class D from Chitinophaga pinensis by Serial Crystallography
To Be Published
8A8U
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Mycobacterium tuberculosis ClpC1 hexamer structure
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
著者Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
登録日2022-06-24
公開日2022-10-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8A8V
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Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
著者Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
登録日2022-06-24
公開日2022-10-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
7JOY
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Product structure of SARS-CoV-2 Mpro C145A mutant in complex with its C-terminal autoprocessing sequence.
分子名称: 3C-like proteinase
著者Lee, J, Worrall, L.J, Paetzel, M, Strynadka, N.C.J.
登録日2020-08-07
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site.
Nat Commun, 11, 2020
8A8W
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Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
著者Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
登録日2022-06-24
公開日2022-10-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
5DAB
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Crystal structure of FTO-IN115
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, CHLORIDE ION, ...
著者Chai, J, Zhou, B, Liu, W, Han, Z, Niu, T.
登録日2015-08-19
公開日2016-08-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of FTO-IN115
To Be Published
1K4B
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STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES
分子名称: 5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3'
著者Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J.
登録日2001-10-07
公開日2001-12-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
8KG6
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Yeast replisome in state I
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
5JBW
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Crystal structure of LiuC
分子名称: 3-hydroxybutyryl-CoA dehydratase
著者Bock, T, Reichelt, J, Mueller, R, Blankenfeldt, W.
登録日2016-04-14
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus xanthus, Reveals Insights into Specificity and Catalysis.
Chembiochem, 17, 2016
1K9S
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PURINE NUCLEOSIDE PHOSPHORYLASE FROM E. COLI IN COMPLEX WITH FORMYCIN A DERIVATIVE AND PHOSPHATE
分子名称: 2-(7-AMINO-6-METHYL-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 2-HYDROXYMETHYL-5-(7-METHYLAMINO-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, ...
著者Koellner, G, Bzowska, A, Wielgus-Kutrowska, B, Luic, M, Steiner, T, Saenger, W, Stepinski, J.
登録日2001-10-30
公開日2001-11-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.
J.Mol.Biol., 315, 2002
3C7V
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Structural Insight into the Kinetics and Delta-Cp of interactions between TEM-1 Beta-Lactamase and BLIP
分子名称: Beta-lactamase, Beta-lactamase inhibitory protein
著者Wang, J, Chow, D.-C.
登録日2008-02-08
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural insight into the kinetics and DeltaCp of interactions between TEM-1 beta-lactamase and beta-lactamase inhibitory protein (BLIP)
J.Biol.Chem., 284, 2009
7LNJ
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CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA
分子名称: DNA Strand 1, DNA Strand 2, Site-specific DNA-methyltransferase (adenine-specific)
著者Horton, J.R, Cheng, X, Zhou, J.
登録日2021-02-07
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Clostridioides difficile specific DNA adenine methyltransferase CamA squeezes and flips adenine out of DNA helix.
Nat Commun, 12, 2021
5JJR
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Dengue 3 NS5 protein with compound 29
分子名称: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-4-methoxy-2-methyl-N-[(quinolin-8-yl)sulfonyl]benzamide, DI(HYDROXYETHYL)ETHER, ...
著者Lescar, J, El Sahili, A.
登録日2016-04-25
公開日2016-07-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Plos Pathog., 12, 2016
1O8Q
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The active site of the molybdenum cofactor biosenthetic protein domain Cnx1G
分子名称: MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN
著者Kuper, J, Winking, J, Hecht, H.J, Schwarz, G, Mendel, R.R.
登録日2002-11-28
公開日2003-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Active Site of the Molybdenum Cofactor Biosynthetic Protein Domain Cnx1G
Arch.Biochem.Biophys., 411, 2003
4R11
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A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
分子名称: Cadherin-related hmr-1, IODIDE ION, Protein humpback-2
著者Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
登録日2014-08-03
公開日2015-04-29
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
5JCS
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CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E.
登録日2016-04-15
公開日2016-11-16
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Nat.Struct.Mol.Biol., 23, 2016
1FTS
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SIGNAL RECOGNITION PARTICLE RECEPTOR FROM E. COLI
分子名称: FTSY
著者Montoya, G, Svensson, C, Luirink, J, Sinning, I.
登録日1996-11-20
公開日1998-05-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the NG domain from the signal-recognition particle receptor FtsY.
Nature, 385, 1997
3C9P
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Crystal structure of uncharacterized protein SP1917
分子名称: 1,2-ETHANEDIOL, Uncharacterized protein SP1917
著者Chang, C, Zhou, M, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-02-18
公開日2008-02-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of uncharacterized protein SP1917.
To be Published
1K73
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Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit
分子名称: 23S RRNA, 5S RRNA, ANISOMYCIN, ...
著者Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
登録日2001-10-18
公開日2003-07-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
3BOG
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Snow Flea Antifreeze Protein Quasi-racemate
分子名称: 6.5 kDa glycine-rich antifreeze protein, UNKNOWN LIGAND
著者Pentelute, B.L, Kent, S.B.H, Gates, Z.P, Tereshko, V, Kossiakoff, A.A, Kurutz, J, Dashnau, J, Vaderkooi, J.M.
登録日2007-12-17
公開日2008-09-23
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers
J.Am.Chem.Soc., 130, 2008

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件を2024-08-14に公開中

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