8AMV
 
 | | RepB pMV158 hexamer | | 分子名称: | PHOSPHATE ION, Replication protein RepB, SODIUM ION | | 著者 | Machon, C, Amodio, J, Boer, R.D, Ruiz-Maso, J.A, del Solar, G, Coll, M. | | 登録日 | 2022-08-04 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Structures of pMV158 replication initiator RepB with and without DNA reveal a flexible dual-function protein.
Nucleic Acids Res., 51, 2023
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7KN0
 | | Structure of the integrin aIIb(W968V)b3 transmembrane complex | | 分子名称: | Integrin alpha-IIb, Integrin beta-3 | | 著者 | Situ, A.J, Kim, J, An, W, Kim, C, Ulmer, T.S. | | 登録日 | 2020-11-03 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insight Into Pathological Integrin alpha IIb beta 3 Activation From Safeguarding The Inactive State.
J.Mol.Biol., 433, 2021
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1GFH
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-12-04 | | 公開日 | 2000-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
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2Y87
 | | Native VIM-7. Structural and computational investigations of VIM-7: Insights into the substrate specificity of VIM metallo-beta- lactamases | | 分子名称: | MAGNESIUM ION, METALLO-B-LACTAMASE, UNKNOWN ATOM OR ION, ... | | 著者 | Saradhi, P, Leiros, H.-K.S, Ahmad, R, Spencer, J, Leiros, I, Walsh, T.R, Sundsfjord, A, Samuelsen, O. | | 登録日 | 2011-02-03 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural and Computational Investigations of Vim- 7: Insights Into the Substrate Specificity of Vim Metallo-Beta-Lactamases
J.Mol.Biol., 411, 2011
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8AMU
 | | RepB pMV158 OBD domain bound to DDR region | | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*GP*TP*CP*GP*CP*CP*GP*AP*AP*AP*AP*GP*TP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*AP*CP*TP*TP*TP*TP*CP*GP*GP*CP*GP*AP*CP*TP*TP*TP*T)-3'), MANGANESE (II) ION, ... | | 著者 | Amodio, J, Machon, C, Boer, R.D, Ruiz-Maso, J.A, del Solar, G, Coll, M. | | 登録日 | 2022-08-04 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of pMV158 replication initiator RepB with and without DNA reveal a flexible dual-function protein.
Nucleic Acids Res., 51, 2023
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1GFT
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-12-04 | | 公開日 | 2000-12-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
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8AFG
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3J2A
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (13.1 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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2YF0
 | | Human Myotubularin related protein 6 (MTMR6) | | 分子名称: | MYOTUBULARIN-RELATED PROTEIN 6, SULFATE ION | | 著者 | Moche, M, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Kouznetsova, E, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, VanDenBerg, S, Wahlberg, E, Weigelt, J, Welin, M, Nordlund, P. | | 登録日 | 2011-03-31 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structure of Human Mtmr6
To be Published
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5KBS
 | | Cryo-EM structure of GluA2-0xSTZ at 8.7 Angstrom resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | | 登録日 | 2016-06-03 | | 公開日 | 2016-07-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016
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8J6F
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8B0Q
 | | Deinococcus radiodurans UvrC C-terminal half | | 分子名称: | UvrABC system protein C | | 著者 | Timmins, J, Stelter, M. | | 登録日 | 2022-09-08 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional insights into the activation of the dual incision activity of UvrC, a key player in bacterial NER.
Nucleic Acids Res., 51, 2023
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8JBW
 | | Crystal structure of ZtHPPD-(+)-Usnic acid complex | | 分子名称: | (9bR)-2,6-diethanoyl-8,9b-dimethyl-3,7,9-tris(oxidanyl)dibenzofuran-1-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | | 著者 | Lin, H.-Y, Dong, J, Yang, G.-F. | | 登録日 | 2023-05-09 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery and Development of 4-Hydroxyphenylpyruvate Dioxygenase as a Novel Crop Fungicide Target.
J.Agric.Food Chem., 71, 2023
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5CWW
 | | Crystal structure of the Chaetomium thermophilum heterotrimeric Nup82 NTD-Nup159 TAIL-Nup145N APD complex | | 分子名称: | Nucleoporin NUP145N, Nucleoporin NUP159, Nucleoporin NUP82 | | 著者 | Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-07-28 | | 公開日 | 2015-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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8J0O
 | | cryo-EM structure of human EMC and VDAC | | 分子名称: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | | 著者 | Li, M, Zhang, C, Wu, J, Lei, M. | | 登録日 | 2023-04-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural insights into human EMC and its interaction with VDAC.
Aging (Albany NY), 16, 2024
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4DK5
 | | Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine inhibitor | | 分子名称: | 4-(2-[(6-methoxypyridin-3-yl)amino]-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | | 著者 | Whittington, D.A, Tang, J, Yakowec, P. | | 登録日 | 2012-02-03 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases.
J.Med.Chem., 55, 2012
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4O7T
 | | SAICAR synthetase (Type-2) in complex with ADP, ASP and TMP | | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ASPARTIC ACID, ... | | 著者 | Manjunath, K, Jeyakanthan, J, Sekar, K. | | 登録日 | 2013-12-26 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | SAICAR synthetase (Type-2) in complex with ADP, ASP and TMP
To be Published
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5CZ3
 | | Crystal Structure of Myxoma Virus M64 | | 分子名称: | BETA-MERCAPTOETHANOL, M64R | | 著者 | Krumm, B.E, Meng, X, Li, Y, Xiang, Y, Deng, J. | | 登録日 | 2015-07-31 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
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3J2F
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (17.6 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.
Nucleic Acids Res., 41, 2013
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7LGP
 | | DapE enzyme from Shigella flexneri | | 分子名称: | CHLORIDE ION, SODIUM ION, Succinyl-diaminopimelate desuccinylase, ... | | 著者 | Osipiuk, J, Endres, M, Becker, D.P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2021-01-20 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | DapE enzyme from Shigella flexneri
To Be Published
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8J23
 | | Cryo-EM structure of FFAR2 complex in apo state | | 分子名称: | Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Tai, L, Li, F, Sun, X, Tang, W, Wang, J. | | 登録日 | 2023-04-14 | | 公開日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular recognition and activation mechanism of short chain fatty acid receptors FFAR2 and FFAR3
To Be Published
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8B2T
 | | SARS-CoV-2 Main Protease (Mpro) in complex with nirmatrelvir alkyne | | 分子名称: | 3C-like proteinase nsp5, Nirmatrelvir (reacted form) | | 著者 | Owen, C.D, Crawshaw, A.D, Warren, A.J, Trincao, J, Zhao, Y, Brewitz, L, Malla, T.R, Salah, E, Petra, L, Strain-Damerell, C, Schofield, C.J, Walsh, M.A. | | 登録日 | 2022-09-14 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | | 主引用文献 | Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine.
J.Med.Chem., 66, 2023
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5JQB
 | | Crystal structure of Ebola glycoprotein in complex with ibuprofen | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, Envelope glycoprotein 2, ... | | 著者 | Zhao, Y, Ren, J, Stuart, D.I. | | 登録日 | 2016-05-04 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Toremifene interacts with and destabilizes the Ebola virus glycoprotein.
Nature, 535, 2016
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3BAG
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1J9K
 | | CRYSTAL STRUCTURE OF SURE PROTEIN FROM T.MARITIMA IN COMPLEX WITH TUNGSTATE | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, STATIONARY PHASE SURVIVAL PROTEIN, ... | | 著者 | Suh, S.W, Lee, J.Y, Kwak, J.E, Moon, J. | | 登録日 | 2001-05-27 | | 公開日 | 2001-09-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family.
Nat.Struct.Biol., 8, 2001
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