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PDB: 42289 件

4Y52
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Crystal structure of 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation.
分子名称: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, L, Chong, J, Wang, D.
登録日2015-02-11
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
1GB6
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CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
分子名称: LYSOZYME, SODIUM ION
著者Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
登録日2000-06-26
公開日2000-07-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
5ND1
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Viral evolution results in multiple, surface-allocated enzymatic activities in a fungal double-stranded RNA virus
分子名称: Capsid protein
著者Mata, C.P, Luque, D, Gomez Blanco, J, Rodriguez, J.M, Suzuki, N, Ghabrial, S.A, Carrascosa, J.L, Trus, B.L, Caston, J.R.
登録日2017-03-07
公開日2017-11-29
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Acquisition of functions on the outer capsid surface during evolution of double-stranded RNA fungal viruses.
PLoS Pathog., 13, 2017
5V4N
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Structure of HLA-DR1 with bound alpha3(135-145) peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, alpha3(135-145)-HLA-DRB1*01:01
著者Petersen, J, Rossjohn, J.
登録日2017-03-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.405 Å)
主引用文献Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
8EEY
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Cas7-11 in complex with DR-mismatched target RNA, Csx29 and Csx30
分子名称: Cas7-11, Csx29, Csx30, ...
著者Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F.
登録日2022-09-07
公開日2022-11-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Science, 378, 2022
8DOF
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Pseudomonas aeruginosa MurC with WYH9-2-P - OSA_001044
分子名称: (2R)-2-cyclohexyl-2-[(4-{[5-(propan-2-yl)-1H-pyrazol-3-yl]amino}-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]ethan-1-ol, 1,2-ETHANEDIOL, SULFATE ION, ...
著者Horanyi, P.S, Wang, Y, Todd, M.H, Abendroth, J, Edwards, T, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-07-13
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Pseudomonas aeruginosa MurC with WYH9-2-P - OSA_001044
To Be Published
4YAY
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XFEL structure of human Angiotensin Receptor
分子名称: 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one, Soluble cytochrome b562,Type-1 angiotensin II receptor
著者Zhang, H, Unal, H, Gati, C, Han, G.W, Zatsepin, N.A, James, D, Wang, D, Nelson, G, Weierstall, U, Messerschmidt, M, Williams, G.J, Boutet, S, Yefanov, O.M, White, T.A, Liu, W, Ishchenko, A, Tirupula, K.C, Desnoyer, R, Sawaya, M.C, Xu, Q, Coe, J, Cornrad, C.E, Fromme, P, Stevens, R.C, Katritch, V, Karnik, S.S, Cherezov, V, GPCR Network (GPCR)
登録日2015-02-18
公開日2015-04-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.
Cell, 161, 2015
2CAU
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CANAVALIN FROM JACK BEAN
分子名称: PROTEIN (CANAVALIN)
著者Ko, T.-P, Day, J, Macpherson, A.
登録日1998-11-20
公開日1998-11-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The refined structure of canavalin from jack bean in two crystal forms at 2.1 and 2.0 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
1XAX
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NMR structure of HI0004, a putative essential gene product from Haemophilus influenzae
分子名称: Hypothetical UPF0054 protein HI0004
著者Yeh, D.C, Parsons, J.F, Parsons, L.M, Liu, F, Eisenstein, E, Orban, J, Structure 2 Function Project (S2F)
登録日2004-08-26
公開日2005-01-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of HI0004, a putative essential gene product from Haemophilus influenzae, and comparison with the X-ray structure of an Aquifex aeolicus homolog
Protein Sci., 14, 2005
4YCV
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Crystal structure of cladosporin in complex with plasmodium lysyl-tRNA synthetase
分子名称: Lysine--tRNA ligase, cladosporin
著者Fang, P, Wang, J, Guo, M.
登録日2015-02-20
公開日2015-06-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.406 Å)
主引用文献Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor.
Chem.Biol., 22, 2015
4YDZ
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Stress-induced protein 1 from Caenorhabditis elegans
分子名称: Stress-induced protein 1
著者Fleckenstein, T, Kastenmueller, A, Stein, M.L, Peters, C, Daake, M, Krause, M, Weinfurtner, D, Haslbeck, M, Weinkauf, S, Groll, M, Buchner, J.
登録日2015-02-23
公開日2015-06-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes.
Mol.Cell, 58, 2015
8DQK
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Intermediate resolution structure of barley (1,3;1,4)-beta-glucan synthase CslF6.
分子名称: Cellulose synthase-like CslF6
著者Ho, R, Purushotham, P, Zimmer, J.
登録日2022-07-19
公開日2022-11-30
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Mechanism of mixed-linkage glucan biosynthesis by barley cellulose synthase-like CslF6 (1,3;1,4)-beta-glucan synthase.
Sci Adv, 8, 2022
2CAG
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CATALASE COMPOUND II
分子名称: CATALASE COMPOUND II, PROTOPORPHYRIN IX CONTAINING FE
著者Gouet, P, Jouve, H.M, Hajdu, J.
登録日1996-06-12
公開日1996-12-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy.
Nat.Struct.Biol., 3, 1996
2CTH
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CYTOCHROME C3 FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH
分子名称: CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE
著者Simoes, P, Matias, P.M, Morais, J, Wilson, K, Dauter, Z, Carrondo, M.A.
登録日1997-06-18
公開日1997-12-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Refinement of the Three-Dimensional Structures of Cytochromes C3 from Desulfovibrio Vulgaris Hildenborough at 1.67 Angstrom Resolution and from Desulfovibrio Desulfuricans Atcc 27774 at 1.6 Angstrom Resolution
Inorg.Chim.Acta., 273, 1998
8DMO
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Structure of open, inward-facing MsbA from E. coli
分子名称: ATP-binding transport protein MsbA
著者Liu, C, Lyu, J, Laganowsky, A.D, Zhao, M.
登録日2022-07-08
公開日2022-12-14
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for lipid and copper regulation of the ABC transporter MsbA.
Nat Commun, 13, 2022
4YIK
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Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PVU
分子名称: 1-{2-deoxy-3,5-O-[phenyl(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-[(E)-2-phosphonoethenyl]pyrimidine-2,4(1H,3H)-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'(3')-deoxyribonucleotidase, ...
著者Pachl, P, Rezacova, P, Brynda, J.
登録日2015-03-02
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.483 Å)
主引用文献Structure-based design of a bisphosphonate 5'(3')-deoxyribonucleotidase inhibitor
Medchemcomm, 6, 2015
8DMM
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Structure of the vanadate-trapped MsbA bound to KDL
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ADP ORTHOVANADATE, ATP-binding transport protein MsbA
著者Liu, C, Lyu, J, Laganowsky, A.D, Zhao, M.
登録日2022-07-08
公開日2022-12-14
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for lipid and copper regulation of the ABC transporter MsbA.
Nat Commun, 13, 2022
8EFK
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Structure of Lates calcarifer DNA polymerase theta polymerase domain with hairpin DNA
分子名称: 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(P*TP*TP*TP*TP*GP*GP*CP*TP*TP*TP*TP*GP*CP*CP*(2DA))-3'), Lates calcarifer DNA polymerase theta, ...
著者Li, C, Zhu, H, Sun, J, Gao, Y.
登録日2022-09-08
公開日2022-12-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of DNA polymerase theta mediated DNA end joining.
Nucleic Acids Res., 51, 2023
1GHJ
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SOLUTION STRUCTURE OF THE LIPOYL DOMAIN OF THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX FROM AZOTOBACTER VINELAND II, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: E2, THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX
著者Berg, A, Vervoort, J, De Kok, A.
登録日1996-01-16
公開日1997-01-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii.
J.Mol.Biol., 261, 1996
1GBY
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CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
分子名称: LYSOZYME, SODIUM ION
著者Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
登録日2000-06-26
公開日2000-07-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
1RX9
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DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
分子名称: BETA-MERCAPTOETHANOL, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ...
著者Sawaya, M.R, Kraut, J.
登録日1996-10-25
公開日1997-04-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
2C8D
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Structure of the ARTT motif Q212A mutant C3bot1 Exoenzyme (Free state, crystal form I)
分子名称: MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION
著者Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A.
登録日2005-12-03
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
Protein Sci., 17, 2008
8EF9
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Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*C)-3'), ...
著者Li, C, Zhu, H, Sun, J, Gao, Y.
登録日2022-09-08
公開日2022-12-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural basis of DNA polymerase theta mediated DNA end joining.
Nucleic Acids Res., 51, 2023
1RY6
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Crystal Structure of Internal Kinesin Motor Domain
分子名称: INTERNAL KINESIN, SULFATE ION
著者Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R.
登録日2003-12-19
公開日2004-04-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of a kinesin microtubule depolymerization machine.
Embo J., 23, 2004
8DW2
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Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR22, and two antibody Fabs, S309 and CR3022
分子名称: Antibody CR3022 heavy chain, Antibody CR3022 light chain, Antibody S309 heavy chain, ...
著者Kwon, Y.D, Gorman, J, Kwong, P.D.
登録日2022-07-30
公開日2022-12-07
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (4.11 Å)
主引用文献A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023

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