5J6P
| Crystal Structure of Mis18(17-118) from Schizosaccharomyces pombe | 分子名称: | Kinetochore protein mis18, ZINC ION | 著者 | Wang, C, Shao, C, Zhang, M, Zhang, X, Zang, J. | 登録日 | 2016-04-05 | 公開日 | 2017-11-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Mis18(17-118) from Schizosaccharomyces pombe To Be Published
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8CY0
| CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor MC4756 (Compound 178) | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*GP*GP*GP*AP*CP*TP*TP*TP*TP*TP*GP*A)-3'), N-(4-phenylbutyl)adenosine, ... | 著者 | Zhou, J, Horton, J.R, Cheng, X. | 登録日 | 2022-05-22 | 公開日 | 2023-01-11 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. J.Med.Chem., 66, 2023
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8DJV
| The N-terminal domain of PA endonuclease from the influenza H1N1 viral polymerase in complex with 6-Bromo-3-hydroxy-N-methoxy-4-oxo-1,4-dihydropyridine-2-carboxamide | 分子名称: | 6-bromo-3-hydroxy-N-methoxy-4-oxo-1,4-dihydropyridine-2-carboxamide, MANGANESE (II) ION, Polymerase acidic protein | 著者 | Kohlbrand, A.J, Stokes, R.W, Karges, J, Seo, H, Sankaran, B, Cohen, S.M. | 登録日 | 2022-07-01 | 公開日 | 2022-12-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors. Acs Med.Chem.Lett., 14, 2023
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5W69
| HLA-C*06:02 presenting ARFNDLRFV | 分子名称: | ALA-ARG-PHE-ASN-ASP-LEU-ARG-PHE-VAL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Mobbs, J.I, Vivian, J.P, Rossjohn, J. | 登録日 | 2017-06-16 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule. J. Biol. Chem., 292, 2017
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5JBX
| Crystal structure of LiuC in complex with coenzyme A and malonic acid | 分子名称: | 3-hydroxybutyryl-CoA dehydratase, COENZYME A, MALONATE ION | 著者 | Bock, T, Reichelt, J, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-04-14 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus xanthus, Reveals Insights into Specificity and Catalysis. Chembiochem, 17, 2016
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8TBY
| Apo Bcs1, unsymmetrized | 分子名称: | Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-29 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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2NNA
| Structure of the MHC class II molecule HLA-DQ8 bound with a deamidated gluten peptide | 分子名称: | MHC class II antigen, gluten peptide | 著者 | Henderson, K.N, Tye-Din, J.A, Rossjohn, J, Anderson, R.P. | 登録日 | 2006-10-24 | 公開日 | 2007-09-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease Immunity, 27, 2007
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5JCO
| Structure and dynamics of single-isoform recombinant neuronal human tubulin | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Vemu, A, Atherton, J, Spector, J.O, Szyk, A, Moores, C.A, Roll-Mecak, A. | 登録日 | 2016-04-15 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin. J.Biol.Chem., 291, 2016
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1YMO
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5LO9
| Thiosulfate dehydrogenase (TsdBA) from Marichromatium purpuratum - "as isolated" form | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Cytochrome C, ... | 著者 | Brito, J.A, Kurth, J.M, Reuter, J, Flegler, A, Koch, T, Franke, T, Klein, E, Rowe, S, Butt, J.N, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | 登録日 | 2016-08-08 | 公開日 | 2016-10-12 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Electron Accepting Units of the Diheme Cytochrome c TsdA, a Bifunctional Thiosulfate Dehydrogenase/Tetrathionate Reductase. J.Biol.Chem., 291, 2016
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7QUU
| Red1-Iss10 complex | 分子名称: | NURS complex subunit red1, Uncharacterized protein C7D4.14c | 著者 | Mackereth, C.D, Kadlec, J, Laroussi, H. | 登録日 | 2022-01-18 | 公開日 | 2022-09-07 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex. Nat Commun, 13, 2022
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8SUF
| The complex of TOL-1 ectodomain bound to LAT-1 Lectin domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Latrophilin-like protein 1, ... | 著者 | Carmona Rosas, G, Li, J, Arac, D, Ozkan, E. | 登録日 | 2023-05-12 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural basis and functional roles for Toll-like receptor binding to Latrophilin adhesion-GPCR in embryo development To Be Published
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7W5X
| Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Lin, W, Feng, Y, Shi, J. | 登録日 | 2021-11-30 | 公開日 | 2022-10-26 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
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2K95
| Solution structure of the wild-type P2B-P3 pseudoknot of human telomerase RNA | 分子名称: | Telomerase RNA P2b-P3 pseudoknot | 著者 | Kim, N.-K, Zhang, Q, Zhou, J, Theimer, C.A, Peterson, R.D, Feigon, J. | 登録日 | 2008-09-29 | 公開日 | 2008-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure and Dynamics of the Wild-type Pseudoknot of Human Telomerase RNA. J.Mol.Biol., 384, 2008
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8T5U
| ATP-1 state of Bcs1 (C7 symmetrized) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-14 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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5JEC
| Apo-structure of humanised RadA-mutant humRadA33F | 分子名称: | CHLORIDE ION, DNA repair and recombination protein RadA, SULFATE ION | 著者 | Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. | 登録日 | 2016-04-18 | 公開日 | 2016-10-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
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7FC5
| Crystal structure of SARS-CoV-2 RBD and horse ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1 | 著者 | Wang, X.Q, Lan, J, Ge, J.W. | 登録日 | 2021-07-13 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | 主引用文献 | Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2. Structure, 30, 2022
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5JFE
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5JFP
| HIV-1 wild Type protease with GRL-097-13A (a Adamantane P1-Ligand with bis-THF in P2 and isobutylamine in P1') | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-[(3R,5R,7R)-tricyclo[3.3.1.1~3,7~]decan-1-yl]butan-2-yl}carbamate, CHLORIDE ION, Protease, ... | 著者 | Wang, Y.-F, Agniswamy, J, Weber, I.T. | 登録日 | 2016-04-19 | 公開日 | 2016-09-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV-1 Protease Inhibitors: Design, Synthesis, Protein X-ray Structural Studies, and Biological Evaluation. J.Med.Chem., 59, 2016
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7Q6D
| E. coli FtsA 1-405 ATP 3 Ni | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION, ... | 著者 | Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J. | 登録日 | 2021-11-06 | 公開日 | 2022-09-21 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN. Nat Microbiol, 7, 2022
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7F5D
| Crystal structure of BPTF-BRD with ligand DC-BPi-03 bound | 分子名称: | 6-(1H-indol-5-yl)-N-methyl-2-methylsulfonyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | 登録日 | 2021-06-21 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.57150865 Å) | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins To Be Published
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8T14
| ADP-bound Bcs1 (C7 symmetrized) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-01 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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7Q6I
| Vibrio maritimus FtsA 1-396 ATP and FtsN 1-29, bent tetramers in double filament arrangement | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, Cell division protein FtsN (polyAla model), ... | 著者 | Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J. | 登録日 | 2021-11-07 | 公開日 | 2022-09-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN. Nat Microbiol, 7, 2022
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8T7U
| ADP-bound Bcs1 (unsymmetrized) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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2KFB
| The structure of the cataract causing P23T mutant of human gamma-D crystallin | 分子名称: | Gamma-crystallin D | 著者 | Jung, J, Byeon, I.L, Wang, Y, King, J, Gronenborn, A.M. | 登録日 | 2009-02-12 | 公開日 | 2009-07-28 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the cataract-causing P23T mutant of human gammaD-crystallin exhibits distinctive local conformational and dynamic changes. Biochemistry, 48, 2009
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