2PM1
| |
6LD5
| Zika NS5 polymerase domain | 分子名称: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ... | 著者 | El Sahili, A, Lescar, J. | 登録日 | 2019-11-20 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
|
|
3SUZ
| |
4TRH
| The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling | 分子名称: | SidC | 著者 | Hsu, F.S, Luo, X, Qiu, J, Teng, Y, Jin, J, Smolka, M.B, Luo, Z.Q, Mao, Y. | 登録日 | 2014-06-16 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
2PMB
| Crystal structure of predicted nucleotide-binding protein from Vibrio cholerae | 分子名称: | GLYCEROL, PHOSPHATE ION, Uncharacterized protein | 著者 | Patskovsky, Y, Zhan, C, Shi, W, Toro, R, Sauder, J.M, Gilmore, J, Iizuka, M, Maletic, M, Gheyi, T, Wasserman, S.R, Smith, D, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2007-04-20 | 公開日 | 2007-05-08 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal Structure of Predicted Nucleotide-Binding Protein from Vibrio Cholerae. To be Published
|
|
5HLR
| Linalool dehydratase/isomerase: Ldi-apo | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, Linalool dehydratase/isomerase | 著者 | Weidenweber, S, Marmulla, R, Harder, J, Ermler, U. | 登録日 | 2016-01-15 | 公開日 | 2016-04-27 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (1.911 Å) | 主引用文献 | X-ray structure of linalool dehydratase/isomerase from Castellaniella defragrans reveals enzymatic alkene synthesis. Febs Lett., 590, 2016
|
|
4ZF7
| Crystal structure of ferret interleukin-2 | 分子名称: | DI(HYDROXYETHYL)ETHER, Interleukin 2, PENTAETHYLENE GLYCOL, ... | 著者 | Ren, B, Newman, J, McKinstry, W.J, Adams, T.E. | 登録日 | 2015-04-21 | 公開日 | 2015-11-04 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | 主引用文献 | Structural and functional characterisation of ferret interleukin-2. Dev.Comp.Immunol., 55, 2015
|
|
5HML
| Crystal Structure of T5 D15 Protein Co-crystallized with Metal Ions | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Flemming, C.S, Feng, M, Sedelnikova, S.E, Zhang, J, Rafferty, J.B, Sayers, J.R, Artymiuk, P.J. | 登録日 | 2016-01-16 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.482 Å) | 主引用文献 | Direct observation of DNA threading in flap endonuclease complexes. Nat.Struct.Mol.Biol., 23, 2016
|
|
8TR0
| |
3FN8
| |
3FMO
| Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, GLYCEROL, ... | 著者 | Napetschnig, J, Debler, E.W, Blobel, G, Hoelz, A. | 登録日 | 2008-12-22 | 公開日 | 2009-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
6LGM
| |
6TGH
| SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex | 分子名称: | D-SERINE, L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene], ... | 著者 | Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I. | 登録日 | 2019-11-15 | 公開日 | 2020-06-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus To Be Published
|
|
8TQB
| mGluR3 in the presence of the agonist LY379268 and PAM VU6023326 | 分子名称: | (1R,4R,5S,6R)-4-azanyl-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, CALCIUM ION, Metabotropic glutamate receptor 3 | 著者 | Strauss, A, Levitz, J. | 登録日 | 2023-08-06 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of allosteric modulation of metabotropic glutamate receptor activation and desensitization. Biorxiv, 2023
|
|
6TGZ
| IE1 from human cytomegalovirus | 分子名称: | 55 kDa immediate-early protein 1 | 著者 | Schweininger, J, Muller, Y.A. | 登録日 | 2019-11-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers. Plos Pathog., 17, 2021
|
|
4ZGB
| Structure of untreated lipase from Thermomyces lanuginosa at 2.3 A resolution | 分子名称: | Lipase | 著者 | Kumar, M, Sinha, M, Mukherjee, J, Gupta, M.N, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2015-04-22 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enhancement of stability of a lipase by subjecting to three phase partitioning (TPP): structures of native and TPP-treated lipase from Thermomyces lanuginosa Sustain Chem Process, 2015
|
|
2PQX
| |
6LHJ
| Quadruple mutant (N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with C452 (compound 16) and NADPH | 分子名称: | 1-[3-(2-chloranyl-4-fluoranyl-phenoxy)propoxy]-6,6-dimethyl-1,3,5-triazine-2,4-diamine, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Vanichtanankul, J, Vitsupakorn, D. | 登録日 | 2019-12-09 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Flexible diaminodihydrotriazine inhibitors of Plasmodium falciparum dihydrofolate reductase: Binding strengths, modes of binding and their antimalarial activities. Eur.J.Med.Chem., 195, 2020
|
|
3TD0
| |
3TD8
| Structural Analysis of Pneumocystis carinii Dihydrofolate Reductase Complex with NADPH and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine | 分子名称: | 6-{2-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl]-4-methoxyphenyl}hex-5-ynoic acid, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Pace, J, Stewart, E. | 登録日 | 2011-08-10 | 公開日 | 2012-04-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural analysis of Pneumocystis cariniidihydrofolate reductase complexed with NADPH and 2,4-diamino-6-[2-(5-carboxypent-1-yn-1-yl)-5-methoxybenzyl]-5-methylpyrido[2,3-d]pyrimidine. Acta Crystallogr.,Sect.F, 68, 2012
|
|
4RMH
| Human Sirt2 in complex with SirReal2 and Ac-Lys-H3 peptide | 分子名称: | 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide, Ac-Lys-H3 peptide, NAD-dependent protein deacetylase sirtuin-2, ... | 著者 | Rumpf, T, Schiedel, M, Karaman, B, Roessler, C, North, B.J, Lehotzky, A, Olah, J, Ladwein, K.I, Schmidtkunz, K, Gajer, M, Pannek, M, Steegborn, C, Sinclair, D.A, Gerhardt, S, Ovadi, J, Schutkowski, M, Sippl, W, Einsle, O, Jung, M. | 登録日 | 2014-10-21 | 公開日 | 2015-02-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Selective Sirt2 inhibition by ligand-induced rearrangement of the active site. Nat Commun, 6, 2015
|
|
6LJG
| Crassostrea gigas ferritin mutant-D119G | 分子名称: | FE (III) ION, Ferritin | 著者 | Li, H, Zang, J, Tan, X, Wang, Z, Du, M. | 登録日 | 2019-12-15 | 公開日 | 2020-12-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Crassostrea gigas ferritin mutant-D119G To Be Published
|
|
6LJP
| Crystal structure of human galectin-16 | 分子名称: | Galectin-16 | 著者 | Su, J. | 登録日 | 2019-12-17 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity. Biochim Biophys Acta Gen Subj, 1865, 2020
|
|
5HH5
| |
6TE2
| Crystal structure of human protein kinase CK2alpha' (CSNK2A2 gene product) in complex with the 2-aminothiazole-type inhibitor 17 | 分子名称: | 3-[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]benzoic acid, Casein kinase II subunit alpha' | 著者 | Niefind, K, Lindenblatt, D, Jose, J, Applegate, V.M, Nickelsen, A. | 登録日 | 2019-11-11 | 公開日 | 2020-07-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (0.922 Å) | 主引用文献 | Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2-Aminothiazole Compounds on Protein Kinase CK2. J.Med.Chem., 63, 2020
|
|