6TGH

SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex

Summary for 6TGH

• Entry DOI: 10.2210/pdb6tgh/pdb
• Descriptor: Serine hydroxymethyltransferase, SODIUM ION, L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene], ... (6 entities in total)
• Functional Keywords: pyridoxal phosphate; x-ray crystallography; hydroxymethyltransferase; proton abstraction; tetrahydrofolate-independent, transferase
• Biological source: Streptococcus thermophilus
• Total number of polymer chains: 4
• Total formula weight: 181218.89

Authors

Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. (deposition date: 2019-11-15, release date: 2020-06-03, Last modification date: 2024-01-24)

• Primary citation: Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I.; Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.12 Å)