6TGH
SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, B, D) | Serine hydroxymethyltransferase | polymer | 415 | 44944.8 | 4 | UniProt (Q5MCK9) Pfam (PF00464) UniProt (by SIFTS) (Q5M0B4) | Streptococcus thermophilus | Serine methylase |
| 2 | E, G, J (A, C, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 3 | F, K (A, B) | L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene] | non-polymer | 333.2 | 2 | Chemie (EVM) | |||
| 4 | H, L (C, D) | D-SERINE | non-polymer | 105.1 | 2 | Chemie (DSN) | |||
| 5 | I, M (C, D) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 6 | N, O, P, Q (A, C, B, D) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, C, B, D: 2 - 416 (UniProt: Q5MCK9)
| PDB | External Database | Details |
|---|---|---|
| Thr 55 | Tyr 55 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 179779.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1439.9 | |
| All* | Total formula weight | 181218.9 |
