3HS4
| Human carbonic anhydrase II complexed with acetazolamide | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Robbins, A.H, Genis, C, Domsic, J, Sippel, K.H, Agbandje-McKenna, M, McKenna, R. | 登録日 | 2009-06-10 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design. Acta Crystallogr.,Sect.F, 65, 2009
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7RID
| Griffithsin variant Y28A | 分子名称: | Griffithsin | 著者 | Zhao, G, Sun, J, Bewley, C.A. | 登録日 | 2021-07-19 | 公開日 | 2022-05-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
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6QJH
| Cryo-EM structure of heparin-induced 2N4R tau snake filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
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2I81
| Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced | 分子名称: | 2-Cys Peroxiredoxin | 著者 | Artz, J.D, Qiu, W, Dong, A, Lew, J, Ren, H, Zhao, Y, Kozieradski, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | 登録日 | 2006-08-31 | 公開日 | 2006-09-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced To be published
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6QJM
| Cryo-EM structure of heparin-induced 2N4R tau twister filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
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6QJQ
| Cryo-EM structure of heparin-induced 2N3R tau filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
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6WW3
| Crystal structure of HERC2 ZZ domain in complex with SUMO1 tail | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SUMO1 linked HERC2 ZZ domain (Small ubiquitin-related modifier 1,E3 ubiquitin-protein ligase HERC2), ... | 著者 | Liu, J, Vann, K.R, Kutateladze, T.G. | 登録日 | 2020-05-07 | 公開日 | 2020-08-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.096 Å) | 主引用文献 | Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1. Structure, 28, 2020
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7R3Q
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7ZOD
| 70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | 登録日 | 2022-04-25 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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6WZ4
| Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Asp at pH 6. Covalent acyl-enzyme intermediate | 分子名称: | ASPARTIC ACID, Glutaminase-asparaginase | 著者 | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | 登録日 | 2020-05-13 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria. Sci Rep, 10, 2020
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7ZHD
| Crystal structure of CtaZ in complex with Closthioamide | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, Transcription activator effector binding, ... | 著者 | Gude, F, Molloy, E.M, Horch, T, Dell, M, Dunbar, K.L, Krabbe, J, Groll, M, Hertweck, C. | 登録日 | 2022-04-06 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria. Angew.Chem.Int.Ed.Engl., 61, 2022
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6WZX
| GID4 in complex with IGLWKS peptide | 分子名称: | Glucose-induced degradation protein 4 homolog, ILE-GLY-LEU-TRP-LYS peptide, UNKNOWN ATOM OR ION | 著者 | Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2020-05-14 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Recognition of nonproline N-terminal residues by the Pro/N-degron pathway. Proc.Natl.Acad.Sci.USA, 117, 2020
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7ZH8
| DYRK1a in Complex with a Bromo-Triazolo-Pyridine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-bromanyl-3H-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ... | 著者 | Dammann, M, Stahlecker, J, Stehle, T, Boeckler, F.M. | 登録日 | 2022-04-05 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes. J.Med.Chem., 65, 2022
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7ZQ5
| 70S E. coli ribosome with truncated uL23 and uL24 loops | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | 登録日 | 2022-04-29 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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6QFC
| Structure of an anti-Mcl1 scFv | 分子名称: | DIMETHYL SULFOXIDE, Induced myeloid leukemia cell differentiation protein Mcl-1, scFv55 | 著者 | Luptak, J. | 登録日 | 2019-01-09 | 公開日 | 2019-11-06 | 最終更新日 | 2019-11-13 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1. Acta Crystallogr D Struct Biol, 75, 2019
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8T14
| ADP-bound Bcs1 (C7 symmetrized) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-01 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8TBY
| Apo Bcs1, unsymmetrized | 分子名称: | Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-29 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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7ZHE
| Crystal structure of CtaZ from Ruminiclostridium cellulolyticum | 分子名称: | GLYCEROL, SODIUM ION, Transcription activator effector binding | 著者 | Gude, F, Molloy, E.M, Horch, T, Dell, M, Dunbar, K.L, Krabbe, J, Groll, M, Hertweck, C. | 登録日 | 2022-04-06 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria. Angew.Chem.Int.Ed.Engl., 61, 2022
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7RKG
| Griffithsin mutant Y28W | 分子名称: | Griffithsin, alpha-D-mannopyranose | 著者 | Zhao, G, Sun, J, Bewley, C. | 登録日 | 2021-07-22 | 公開日 | 2022-05-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
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8T5U
| ATP-1 state of Bcs1 (C7 symmetrized) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-14 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8T7U
| ADP-bound Bcs1 (unsymmetrized) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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6WR4
| Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery | 分子名称: | Autophagy-related protein 9A, Lauryl Maltose Neopentyl Glycol | 著者 | Guardia, C.M, Tan, X, Lian, T, Rana, M.S, Zhou, W, Christenson, E.T, Lowry, A.J, Faraldo-Gomez, J.D, Bonifacino, J.S, Jiang, J, Banerjee, A. | 登録日 | 2020-04-29 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery. Cell Rep, 31, 2020
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3C5Z
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6QJU
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2NVV
| Crystal Structure of the Putative Acetyl-CoA hydrolase/transferase PG1013 from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR16. | 分子名称: | Acetyl-CoA hydrolase/transferase family protein, ZINC ION | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Yong, W, Ho, C.K, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-11-13 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of the Putative Acetyl-CoA hydrolase/transferase PG1013 from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR16 To be Published
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