7NYI
 
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3ZRQ
 | | Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from Sulfolobus solfataricus | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, SERINE-PYRUVATE AMINOTRANSFERASE (AGXT) | | 著者 | Sayer, C, Bommer, M, Isupov, M.N, Ward, J, Littlechild, J. | | 登録日 | 2011-06-17 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure and Substrate Specificity of the Thermophilic Serine:Pyruvate Aminotransferase from Sulfolobus Solfataricus
Acta Crystallogr.,Sect.D, 68, 2012
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1T01
 | | Vinculin complexed with the VBS1 helix from talin | | 分子名称: | Talin 1, unnamed protein product | | 著者 | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | | 登録日 | 2004-04-07 | | 公開日 | 2004-08-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
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7O30
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5U7I
 | | PDE2 catalytic domain complexed with inhibitors | | 分子名称: | 4-[3-(4-methoxyphenoxy)azetidin-1-yl]-1-methyl-3-(2-methylpropyl)-1H-pyrazolo[3,4-d]pyrimidine, MAGNESIUM ION, ZINC ION, ... | | 著者 | Pandit, J. | | 登録日 | 2016-12-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor.
J. Med. Chem., 60, 2017
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3DL3
 | | Crystal structure of the tellurite resistance protein TehB. Northeast Structural Genomics Consortium target VfR98 . | | 分子名称: | Tellurite resistance protein B | | 著者 | Kuzin, A.P, Su, M, Seetharaman, J, Wang, D, Mao, L, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-06-26 | | 公開日 | 2008-08-26 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the tellurite resistance protein TehB. Northeast Structural Genomics Consortium target VfR98.
To be Published
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1H2O
 | | SOLUTION STRUCTURE OF THE MAJOR CHERRY ALLERGEN PRU AV 1 MUTANT E45W | | 分子名称: | MAJOR ALLERGEN PRU AV 1 | | 著者 | Neudecker, P, Lehmann, K, Nerkamp, J, Schweimer, K, Sticht, H, Boehm, M, Scheurer, S, Vieths, S, Roesch, P. | | 登録日 | 2002-08-12 | | 公開日 | 2003-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational Epitope Analysis of Pru Av 1 and Api G 1, the Major Allergens of Cherry (Prunus Avium) and Celery (Apium Graveolens): Correlating Ige Reactivity with Three-Dimensional Structure
Biochem.J., 376, 2003
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3DM6
 | | Beta-secretase 1 complexed with statine-based inhibitor | | 分子名称: | 5-[[(2S)-2-[[(3R,4S)-5-(3,5-difluorophenoxy)-3-hydroxy-4-[[3-(methyl-methylsulfonyl-amino)-5-[[(1R)-1-phenylethyl]carbamoyl]phenyl]carbonylamino]pentanoyl]amino]-3-methyl-butanoyl]amino]benzene-1,3-dicarboxylic acid, Beta-secretase 1, ISOPROPYL ALCOHOL | | 著者 | Lindberg, J, Borkakoti, N, Nystrom, S. | | 登録日 | 2008-06-30 | | 公開日 | 2008-12-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues
Bioorg.Med.Chem., 16, 2008
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7O4H
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5Z6O
 | | Crystal structure of Penicillium cyclopium protease | | 分子名称: | CALCIUM ION, phenylmethanesulfonic acid, protease | | 著者 | Ko, T.-P, Koszelak, S, Ng, J, Day, J, Greenwood, A, McPherson, A. | | 登録日 | 2018-01-24 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The crystallographic structure of the subtilisin protease from Penicillium cyclopium.
Biochemistry, 36, 1997
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2PSB
 | | Crystal structure of YerB protein from Bacillus subtilis. NorthEast Structural Genomics target SR586 | | 分子名称: | YerB protein | | 著者 | Seetharaman, J, Chen, Y, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-05-04 | | 公開日 | 2007-05-15 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of YerB protein from Bacillus subtilis.
To be Published
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1T3E
 | | Structural basis of dynamic glycine receptor clustering | | 分子名称: | 49-mer fragment of Glycine receptor beta chain, Gephyrin, SULFATE ION | | 著者 | Sola, M, Bavro, V.N, Timmins, J, Franz, T, Ricard-Blum, S, Schoehn, G, Ruigrok, R.W.H, Paarmann, I, Saiyed, T, O'Sullivan, G.A. | | 登録日 | 2004-04-26 | | 公開日 | 2004-07-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural basis of dynamic glycine receptor clustering by gephyrin
Embo J., 23, 2004
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2PWT
 | | Crystal structure of the bacterial ribosomal decoding site complexed with aminoglycoside containing the L-HABA group | | 分子名称: | 22-mer of the ribosomal decoding site, DOUBLY FUNCTIONALIZED PAROMOMYCIN PM-II-162 | | 著者 | Kondo, J, Pachamuthu, K, Francois, B, Szychowski, J, Hanessian, S, Westhof, E. | | 登録日 | 2007-05-13 | | 公開日 | 2007-09-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the Bacterial Ribosomal Decoding Site Complexed with a Synthetic Doubly Functionalized Paromomycin Derivative: a New Specific Binding Mode to an A-Minor Motif Enhances in vitro Antibacterial Activity
Chemmedchem, 2, 2007
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3DPR
 | | Human rhinovirus 2 bound to a concatamer of the VLDL receptor module V3 | | 分子名称: | CALCIUM ION, LAURIC ACID, LDL-receptor class A 3, ... | | 著者 | Querol-Audi, J, Pous, J, Fita, I, Verdaguer, N. | | 登録日 | 2008-07-09 | | 公開日 | 2009-04-07 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition
Febs Lett., 583, 2009
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3DTD
 | | Crystal structure of invasion associated protein b from bartonella henselae | | 分子名称: | GLYCEROL, Invasion-associated protein B | | 著者 | Patskovsky, Y, Ozyurt, S, Freeman, J, Slocombe, A, Groshong, C, Koss, J, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-07-14 | | 公開日 | 2008-09-09 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure of Invasion Associated Protein B from Bartonella Henselae.
To be Published
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3HMW
 | | Crystal structure of ustekinumab FAB | | 分子名称: | CADMIUM ION, USTEKINUMAB FAB HEAVY CHAIN, USTEKINUMAB FAB LIGHT CHAIN | | 著者 | Luo, J. | | 登録日 | 2009-05-29 | | 公開日 | 2010-06-09 | | 最終更新日 | 2015-07-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab.
J.Mol.Biol., 402, 2010
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6C1A
 | | MBD2 in complex with methylated DNA | | 分子名称: | Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION, complement to dna strand 1, ... | | 著者 | Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-01-04 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
J. Biol. Chem., 293, 2018
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1GOJ
 | | Structure of a fast kinesin: Implications for ATPase mechanism and interactions with microtubules | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION | | 著者 | Song, Y.-H, Marx, A, Muller, J, Woehlke, G, Schliwa, M, Krebs, A, Hoenger, A, Mandelkow, E. | | 登録日 | 2001-10-21 | | 公開日 | 2001-11-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a Fast Kinesin: Implications for ATPase Mechanism and Interactions with Microtubules
Embo J., 20, 2001
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6C1T
 | | MBD2 in complex with a partially methylated DNA | | 分子名称: | 12-mer DNA, GLYCEROL, Methyl-CpG-binding domain protein 2, ... | | 著者 | Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-01-05 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
J. Biol. Chem., 293, 2018
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3DX8
 | | Crystal Structure of B*4405 presenting a 10mer EBV epitope | | 分子名称: | Beta-2-microglobulin, EBV decapeptide epitope, GLYCEROL, ... | | 著者 | Archbold, J.K, Ely, L.K, Rossjohn, J. | | 登録日 | 2008-07-23 | | 公開日 | 2009-01-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
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2Q2G
 | | Crystal structure of dimerization domain of HSP40 from Cryptosporidium parvum, cgd2_1800 | | 分子名称: | Heat shock 40 kDa protein, putative (fragment), SULFATE ION | | 著者 | Wernimont, A.K, Lew, J, Lin, L, Hassanali, A, Kozieradzki, I, Wasney, G, Vedadi, M, Walker, J.R, Zhao, Y, Schapira, M, Bochkarev, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-05-28 | | 公開日 | 2007-06-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of dimerization domain of HSP40 from Cryptosporidium parvum, cgd2_1800.
To be Published
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6BWQ
 | | LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, in complex with MnCTP | | 分子名称: | CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | 著者 | Fellner, M, Hausinger, R.P, Hu, J. | | 登録日 | 2017-12-15 | | 公開日 | 2018-06-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.
J. Biol. Chem., 293, 2018
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1TLY
 | | Tsx structure | | 分子名称: | Nucleoside-specific channel-forming protein tsx | | 著者 | Ye, J, van den Berg, B. | | 登録日 | 2004-06-10 | | 公開日 | 2004-08-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Crystal structure of the bacterial nucleoside transporter Tsx.
Embo J., 23, 2004
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6BGF
 | | Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase | | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... | | 著者 | Liu, A, Li, J, Shin, I. | | 登録日 | 2017-10-28 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.
Nat.Chem.Biol., 14, 2018
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1UYN
 | | Translocator domain of autotransporter NalP from Neisseria meningitidis | | 分子名称: | NALP, PENTAETHYLENE GLYCOL MONODECYL ETHER, SULFATE ION | | 著者 | Oomen, C.J, Van Ulsen, P, Van Gelder, P, Feijen, M, Tommassen, J, Gros, P. | | 登録日 | 2004-03-02 | | 公開日 | 2004-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the Translocator Domain of a Bacterial Autotransporter
Embo J., 23, 2004
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