6BWQ
LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, in complex with MnCTP
Summary for 6BWQ
| Entry DOI | 10.2210/pdb6bwq/pdb |
| Descriptor | Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, MANGANESE (II) ION, CYTIDINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | lar, nickel transferase, larc, hexamer, trimer, ctp, nickel, lactate, lactate racemization, lactate racemase, metal binding protein |
| Biological source | Lactobacillus plantarum |
| Total number of polymer chains | 2 |
| Total formula weight | 35040.58 |
| Authors | Fellner, M.,Hausinger, R.P.,Hu, J. (deposition date: 2017-12-15, release date: 2018-06-20, Last modification date: 2023-10-04) |
| Primary citation | Desguin, B.,Fellner, M.,Riant, O.,Hu, J.,Hausinger, R.P.,Hols, P.,Soumillion, P. Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase. J. Biol. Chem., 293:12303-12317, 2018 Cited by PubMed: 29887527DOI: 10.1074/jbc.RA118.003741 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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