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PDB: 42254 件

7Y0L
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SulE-S209A
分子名称: Alpha/beta fold hydrolase, GLYCEROL, METHYL 2-[({[(4-METHOXY-6-METHYL-1,3,5-TRIAZIN-2-YL)AMINO]CARBONYL}AMINO)SULFONYL]BENZOATE
著者Liu, B, Ran, T, He, J, Wang, W.
登録日2022-06-05
公開日2023-08-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity.
Nat Commun, 14, 2023
6R14
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Structure of kiteplatinated dsDNA
分子名称: Kiteplatin, Kiteplatinated DNA oligomer, chain A, ...
著者Margiotta, N, Papadia, P, Kubicek, K, Krejcikova, M, Gkionis, K, Sponer, J.
登録日2019-03-13
公開日2020-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of kiteplatinated DNA
To Be Published
6L8F
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Crystal structure of heterotetrameric complex of YoeB-YefM toxin-antitoxin from Staphylococcus aureus.
分子名称: Antitoxin, YoeB
著者Yue, J, Xue, L.
登録日2019-11-06
公開日2020-09-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system.
Nucleic Acids Res., 48, 2020
6L90
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Crystal structure of ugt transferase enzyme
分子名称: Glycosyltransferase, SULFATE ION
著者Li, J, Shan, N, Yang, J.G, Liu, W.D, Sun, Y.X.
登録日2019-11-07
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Efficient O-Glycosylation of Triterpenes Enabled by Protein Engineering of Plant Glycosyltransferase UGT74AC1
Acs Catalysis, 2020
6LEB
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Staphylococcus aureus surface protein SdrC mutant-P366H
分子名称: GLYCEROL, MAGNESIUM ION, Ser-Asp rich fibrinogen-binding, ...
著者Hang, T, Zhang, M, Wang, J.
登録日2019-11-25
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural insights into the intermolecular interaction of the adhesin SdrC in the pathogenicity of Staphylococcus aureus.
Acta Crystallogr.,Sect.F, 77, 2021
2RDO
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50S subunit with EF-G(GDPNP) and RRF bound
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
著者Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J.
登録日2007-09-24
公開日2008-03-04
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
8GO9
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BU of 8go9 by Molmil
Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Atypical chemokine receptor 2, ACKR2 (D6R)
分子名称: Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ...
著者Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K.
登録日2022-08-24
公開日2023-12-27
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors.
Science, 383, 2024
6R8E
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SC14 G-hairpin
分子名称: DNA (5'-D(*GP*TP*GP*TP*GP*TP*GP*GP*GP*TP*GP*TP*GP*T)-3')
著者Lenarcic Zivkovic, M, Trantirek, L, Plavec, J.
登録日2019-04-01
公開日2021-02-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Insight into formation propensity of pseudocircular DNA G-hairpins.
Nucleic Acids Res., 49, 2021
6R4K
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Structure of beta-glucosidase A from Paenibacillus polymyxa complexed with a monovalent inhibitor
分子名称: (2~{S},3~{S},4~{R})-2-[[4-[4-[2-[2-(2-azanylidenehydrazinyl)ethoxy]ethoxy]phenyl]-1,2,3-triazol-1-yl]methyl]pyrrolidine-3,4-diol, Beta-glucosidase A
著者Jimenez-Ortega, E, Sanz-Aparicio, J.
登録日2019-03-22
公開日2019-07-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural basis of the inhibition of GH1 beta-glucosidases by multivalent pyrrolidine iminosugars.
Bioorg.Chem., 89, 2019
4FP4
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BU of 4fp4 by Molmil
Crystal structure of isoprenoid synthase a3mx09 (target efi-501993) from pyrobaculum calidifontis
分子名称: GERAN-8-YL GERAN, Polyprenyl synthetase, UNKNOWN ATOM OR ION, ...
著者Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-06-21
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
6A2V
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Crystal structure of Hcp protein
分子名称: Type VI secretion system tube protein Hcp
著者Jobichen, C, Sivaraman, J.
登録日2018-06-13
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.588 Å)
主引用文献Structural basis for the pathogenesis of Campylobacter jejuni Hcp1, a structural and effector protein of the Type VI Secretion System.
FEBS J., 285, 2018
7MRL
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Structure of HIV-1 matrix domain bound to human tRNALys3
分子名称: HIV-1 matrix domain, MAGNESIUM ION, tRNA Lys3
著者Bou-Nader, C, Zhang, J.
登録日2021-05-07
公開日2021-08-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization.
Cell Host Microbe, 29, 2021
4F7H
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BU of 4f7h by Molmil
The crystal structure of kindlin-2 pleckstrin homology domain in free form
分子名称: Fermitin family homolog 2, S,R MESO-TARTARIC ACID
著者Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R.
登録日2012-05-16
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation.
Protein Cell, 3, 2012
6RB0
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BU of 6rb0 by Molmil
STRUCTURE OF ESTER-HYDROLASE EH1AB1 FROM THE METAGENOME OF LAKE ARREO COMPLEXED WITH A DERIVATIVE OF METHYL 4-NITROPHENYL HEXYLPHOSPHONATE
分子名称: EH1AB1, GLYCEROL, methyl hydrogen (R)-hexylphosphonate
著者Cea-Rama, I, Sanz-Aparicio, J.
登録日2019-04-08
公開日2019-12-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Nat Catal, 3, 2020
4FET
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BU of 4fet by Molmil
Catalytic domain of germination-specific lytic tansglycosylase SleB from Bacillus anthracis
分子名称: SODIUM ION, Spore cortex-lytic enzyme prepeptide
著者Jing, X, Heffron, J, Popham, D.L, Schubot, F.D.
登録日2012-05-30
公開日2012-07-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.909 Å)
主引用文献The catalytic domain of the germination-specific lytic transglycosylase SleB from Bacillus anthracis displays a unique active site topology.
Proteins, 80, 2012
8GWK
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BU of 8gwk by Molmil
SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP
分子名称: Helicase, MAGNESIUM ION, Non-structural protein 7, ...
著者Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y.
登録日2022-09-17
公開日2024-02-28
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
7Z01
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Z-SBTubA4 photoswitch bound to tubulin-DARPin D1 complex
分子名称: 2-methoxy-5-[2-(5,6,7-trimethoxy-1,3-benzothiazol-2-yl)ethyl]phenol, CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ...
著者Wranik, M, Weinert, T, Standfuss, J, Steinmetz, M.
登録日2022-02-21
公開日2022-03-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M.
J.Am.Chem.Soc., 144, 2022
7Z02
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Z-SBTub2M photoswitch bound to tubulin-DARPin D1 complex
分子名称: 6-methyl-2-[2-(3,4,5-trimethoxyphenyl)ethyl]-1,3-benzothiazole, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
著者Wranik, M, Weinert, T, Standfuss, J, Steinmetz, M.
登録日2022-02-21
公開日2022-03-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M.
J.Am.Chem.Soc., 144, 2022
6L3U
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BU of 6l3u by Molmil
Human Cx31.3/GJC3 connexin hemichannel in the presence of calcium
分子名称: CALCIUM ION, Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol
著者Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S.
登録日2019-10-15
公開日2020-09-09
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
1AI8
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BU of 1ai8 by Molmil
HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG
分子名称: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN IIIB, ...
著者Skordalakes, E, Dodson, G, Elgendy, S, Goodwin, C.A, Green, D, Tyrrel, R, Scully, M.F, Freyssinet, J, Kakkar, V.V, Deadman, J.
登録日1997-05-01
公開日1997-10-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Protein Sci., 1, 1992
8GKV
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BU of 8gkv by Molmil
Crystal structure of anti-adaptor IraP that regulates RpoS proteolysis
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Shaw, G.X, Gan, J, Suburaman, P, Battesti, A, Zhou, Y.N, Wickner, S, Gottesman, S, Ji, X.
登録日2023-03-20
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Structural and functional study of anti-adaptor IraP-mediated regulation of RpoS proteolysis
to be published
7Z5G
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human apo MATCAP
分子名称: Uncharacterized protein KIAA0895-like
著者Bak, J, Adamoupolos, A, Heidebrecht, T, Perrakis, A.
登録日2022-03-09
公開日2022-05-11
最終更新日2022-06-01
実験手法X-RAY DIFFRACTION (2.113 Å)
主引用文献Posttranslational modification of microtubules by the MATCAP detyrosinase.
Science, 376, 2022
7Z5H
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human Zn MATCAP
分子名称: Uncharacterized protein KIAA0895-like, ZINC ION
著者Bak, J, Adamopoulos, A, Heidebrecht, T, Perrakis, A.
登録日2022-03-09
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Posttranslational modification of microtubules by the MATCAP detyrosinase.
Science, 376, 2022
7Z6S
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MATCAP bound to a human 14 protofilament microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Bak, J, Perrakis, A.
登録日2022-03-14
公開日2022-05-11
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Posttranslational modification of microtubules by the MATCAP detyrosinase.
Science, 376, 2022
6OSM
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Cryo-EM structure of the N-terminally acetylated C-terminal Alpha-synuclein truncation Ac1-103
分子名称: Alpha-synuclein
著者Xiaodan, N, Ryan, P.M, Jiansen, J, Jennifer, C.L.
登録日2019-05-01
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural Insights into alpha-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations.
J.Mol.Biol., 431, 2019

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件を2024-07-10に公開中

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