1X3G
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![BU of 1x3g by Molmil](/molmil-images/mine/1x3g) | Crystal structure of the single-stranded DNA-binding protein from Mycobacterium SMEGMATIS | 分子名称: | CADMIUM ION, Single-strand binding protein | 著者 | Saikrishnan, K, Manjunath, G.P, Singh, P, Jeyakanthan, J, Dauter, Z, Sekar, K, Muniyappa, K, Vijayan, M. | 登録日 | 2005-05-05 | 公開日 | 2005-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association. Acta Crystallogr.,Sect.D, 61, 2005
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6IB2
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![BU of 6ib2 by Molmil](/molmil-images/mine/6ib2) | The structure of MKK7 in complex with the covalent 4-amino-pyrazolopyrimidine 4a | 分子名称: | 1-[(3~{R})-3-[4-azanyl-3-[1-(4-ethanoylphenyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 | 著者 | Wolle, P, Hardick, J, Mueller, M.P, Rauh, D. | 登録日 | 2018-11-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors. J.Med.Chem., 62, 2019
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4ZNM
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![BU of 4znm by Molmil](/molmil-images/mine/4znm) | Crystal structure of SgcC5 protein from Streptomyces globisporus (apo form) | 分子名称: | C-domain type II peptide synthetase, CHLORIDE ION, SODIUM ION | 著者 | Michalska, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Lohman, J, Ma, M, Rudolf, J, Chang, C.-Y, Shen, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2015-05-04 | 公開日 | 2015-05-27 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Crystal structure of SgcC5 protein from Streptomyces globisporus (apo form) To Be Published
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4Q5J
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![BU of 4q5j by Molmil](/molmil-images/mine/4q5j) | Crystal structure of SeMet derivative BRI1 in complex with BKI1 | 分子名称: | BRI1 kinase inhibitor 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein BRASSINOSTEROID INSENSITIVE 1 | 著者 | Wang, J, Wang, J, Chen, L, Wu, J.W, Wang, Z.X. | 登録日 | 2014-04-17 | 公開日 | 2014-10-29 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.772 Å) | 主引用文献 | Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1. Cell Res., 24, 2014
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3HHA
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![BU of 3hha by Molmil](/molmil-images/mine/3hha) | Crystal structure of cathepsin L in complex with AZ12878478 | 分子名称: | ACETATE ION, Cathepsin L1, GLYCEROL, ... | 著者 | Asaad, N, Bethel, P.A, Coulson, M.D, Dawson, J, Ford, S.J, Gerhardt, S, Grist, M, Hamlin, G.A, James, M.J, Jones, E.V, Karoutchi, G.I, Kenny, P.W, Morley, A.D, Oldham, K, Rankine, N, Ryan, D, Wells, S.L, Wood, L, Augustin, M, Krapp, S, Simader, H, Steinbacher, S. | 登録日 | 2009-05-15 | 公開日 | 2009-06-23 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | Dipeptidyl nitrile inhibitors of Cathepsin L. Bioorg.Med.Chem.Lett., 19, 2009
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6RUL
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![BU of 6rul by Molmil](/molmil-images/mine/6rul) | Crystal structure of GFP-LAMA-F98 - a GFP enhancer nanobody with cpDHFR insertion and TMP and NADPH | 分子名称: | GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIETHYLENE GLYCOL, ... | 著者 | Farrants, H, Tarnawski, M, Mueller, T.G, Otsuka, S, Hiblot, J, Koch, B, Kueblbeck, M, Kraeusslich, H.-G, Ellenberg, J, Johnsson, K. | 登録日 | 2019-05-28 | 公開日 | 2020-02-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Chemogenetic Control of Nanobodies. Nat.Methods, 17, 2020
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2Z71
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![BU of 2z71 by Molmil](/molmil-images/mine/2z71) | Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V | 分子名称: | (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, Penicillin acylase | 著者 | Pathak, M.C, Brannigan, J, Dodson, G.G, Suresh, C.G. | 登録日 | 2007-08-10 | 公開日 | 2008-08-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Studies on the catalysis and post translational processing of penicillin V acylase To be published
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3HOH
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![BU of 3hoh by Molmil](/molmil-images/mine/3hoh) | RIBONUCLEASE T1 (THR93GLN MUTANT) COMPLEXED WITH 2'GMP | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | 著者 | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | 登録日 | 1998-09-11 | 公開日 | 1998-09-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Dissection of the structural and functional role of a conserved hydration site in RNase T1. Protein Sci., 8, 1999
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2Z3E
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8HGH
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![BU of 8hgh by Molmil](/molmil-images/mine/8hgh) | Structure of 2:2 PAPP-A.STC2 complex | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-11-14 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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8OM7
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![BU of 8om7 by Molmil](/molmil-images/mine/8om7) | Human Mitochondrial Lon Y186E Mutant ADP Bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | 登録日 | 2023-03-31 | 公開日 | 2024-04-10 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
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8HGG
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![BU of 8hgg by Molmil](/molmil-images/mine/8hgg) | Structure of 2:2 PAPP-A.ProMBP complex | 分子名称: | Bone marrow proteoglycan, Pappalysin-1, ZINC ION | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-11-14 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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8H8C
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![BU of 8h8c by Molmil](/molmil-images/mine/8h8c) | Type VI secretion system effector RhsP in its post-autoproteolysis and dimeric form | 分子名称: | C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein | 著者 | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | 登録日 | 2022-10-22 | 公開日 | 2023-01-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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5XIM
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8H8B
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![BU of 8h8b by Molmil](/molmil-images/mine/8h8b) | Type VI secretion system effector RhsP in its pre-autoproteolysis and monomeric form | 分子名称: | Putative Rhs-family protein | 著者 | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | 登録日 | 2022-10-22 | 公開日 | 2023-01-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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6RZP
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![BU of 6rzp by Molmil](/molmil-images/mine/6rzp) | Multicrystal structure of Proteinase K at room temperature using a multilayer monochromator. | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Sandy, J, Sandy, E, Sanchez-Weatherby, J, Mikolajek, H. | 登録日 | 2019-06-13 | 公開日 | 2019-07-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Protein-to-structure pipeline for ambient-temperature crystallography at VMXi Iucrj, 2023
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8H1A
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2YSW
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![BU of 2ysw by Molmil](/molmil-images/mine/2ysw) | Crystal Structure of the 3-dehydroquinate dehydratase from Aquifex aeolicus VF5 | 分子名称: | 3-dehydroquinate dehydratase | 著者 | Tanaka, T, Kumarevel, T.S, Ebihara, A, Chen, L, Fu, Z.Q, Chrzas, J, Wang, B.C, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-04 | 公開日 | 2007-10-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal Structure of the 3-dehydroquinate dehydratase from Aquifex aeolicus VF5 To be Published
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8H27
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6S16
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![BU of 6s16 by Molmil](/molmil-images/mine/6s16) | T. thermophilus RuvC in complex with Holliday junction substrate | 分子名称: | CHLORIDE ION, Crossover junction endodeoxyribonuclease RuvC, DNA (33-MER), ... | 著者 | Gorecka, K.M, Krepl, M, Szlachcic, A, Poznanski, J, Sponer, J, Nowotny, M. | 登録日 | 2019-06-18 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.409 Å) | 主引用文献 | RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution. Nat Commun, 10, 2019
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8H8A
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![BU of 8h8a by Molmil](/molmil-images/mine/8h8a) | Type VI secretion system effector RhsP in its post-autoproteolysis and monomeric form | 分子名称: | C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein | 著者 | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | 登録日 | 2022-10-22 | 公開日 | 2023-01-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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3I4S
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![BU of 3i4s by Molmil](/molmil-images/mine/3i4s) | CRYSTAL STRUCTURE OF HISTIDINE TRIAD PROTEIN blr8122 FROM Bradyrhizobium japonicum | 分子名称: | GLYCEROL, HISTIDINE TRIAD PROTEIN | 著者 | Patskovsky, Y, Ramagopal, U, Toro, R, Freeman, J, Do, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-07-02 | 公開日 | 2009-07-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | CRYSTAL STRUCTURE OF HISTIDINE TRIAD PROTEIN FROM Bradyrhizobium japonicum To be Published
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8H26
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8H0S
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8OJL
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![BU of 8ojl by Molmil](/molmil-images/mine/8ojl) | Human Mitochondrial Lon Y394E Mutant ADP Bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | 登録日 | 2023-03-24 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
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