3CU8
 
 | | Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome | | 分子名称: | 14-3-3 protein zeta/delta, MAGNESIUM ION, PROPANOIC ACID, ... | | 著者 | Schumacher, B, Weyand, M, Kuhlmann, J, Ottmann, C. | | 登録日 | 2008-04-16 | | 公開日 | 2009-05-05 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol. Cell. Biol., 30, 2010
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6G18
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State C | | 分子名称: | 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, ... | | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2018-03-20 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6G4A
 | | FLN5 (full length) | | 分子名称: | Gelation factor | | 著者 | Waudby, C.A, Wlodarski, T, Karyadi, M.-E, Cassaignau, A.M.E, Chan, S.H.S, Wentink, A.S, Schmidt-Engler, J.M, Camilloni, C, Vendruscolo, M, Cabrita, L.D, Christodoulou, J. | | 登録日 | 2018-03-27 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mapping energy landscapes of a growing filamin domain reveals an intermediate associated with proline isomerization during biosynthesis
To Be Published
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6BK5
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6FM0
 | | Deoxyguanylosuccinate synthase (DgsS) and ATP structure at 1.7 Angstrom resolution | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase | | 著者 | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | | 登録日 | 2018-01-29 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes.
Science, 372, 2021
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6G4S
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State B | | 分子名称: | 40S ribosomal protein S11, 40S ribosomal protein S13, 40S ribosomal protein S14, ... | | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2018-03-28 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6BMI
 | | Crystal Structure of GltPh R397C in complex with L-Serine | | 分子名称: | Glutamate transporter homolog, SERINE, SODIUM ION | | 著者 | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | | 登録日 | 2017-11-14 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
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3D1G
 | | Structure of a small molecule inhibitor bound to a DNA sliding clamp | | 分子名称: | DNA polymerase III subunit beta, [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid | | 著者 | Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M. | | 登録日 | 2008-05-05 | | 公開日 | 2008-07-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3D10
 | | Crystal Structure of S100B in the Calcium and Zinc Loaded State at pH 10.0 | | 分子名称: | CALCIUM ION, Protein S100-B, TRIETHYLENE GLYCOL, ... | | 著者 | Ostendorp, T, Diez, J, Heizmann, C.W, Fritz, G. | | 登録日 | 2008-05-02 | | 公開日 | 2009-04-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping.
Biochim.Biophys.Acta, 1813, 2011
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3D29
 | | Proteasome Inhibition by Fellutamide B | | 分子名称: | (3R)-3-HYDROXYDODECANOIC ACID, Fellutamide B, PRE10 isoform 1, ... | | 著者 | Groll, M, Hines, J, Fahnestock, M, Crews, M.C. | | 登録日 | 2008-05-07 | | 公開日 | 2008-06-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis
Chem.Biol., 15, 2008
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3D65
 | | Crystal structure of Textilinin-1, a Kunitz-type serine protease inhibitor from the Australian Common Brown snake venom, in complex with trypsin | | 分子名称: | CALCIUM ION, Cationic trypsin, Textilinin | | 著者 | Millers, E.-K.I, Masci, P.P, Lavin, M.F, de Jersey, J, Guddat, L.W. | | 登録日 | 2008-05-19 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal structure of Textilinin-1, a Kunitz-type serine protease inhibitor from the Australian Common Brown snake venom, in complex with trypsin
To be Published
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3D6W
 | | LytTr DNA-binding domain of putative methyl-accepting/DNA response regulator from Bacillus cereus. | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | Osipiuk, J, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-05-20 | | 公開日 | 2008-07-15 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray crystal structure of LytTr DNA-binding domain of putative methyl-accepting/DNA response regulator from Bacillus cereus.
To be Published
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3D7F
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6FSA
 | | Beta-Cardiac myosin post-rigor | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ... | | 著者 | Robert-Paganin, J, Auguin, D, Houdusse, A. | | 登録日 | 2018-02-19 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition.
Nat Commun, 9, 2018
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3CEW
 | | Crystal structure of a cupin protein (BF4112) from Bacteroides fragilis. Northeast Structural Genomics Consortium target BfR205 | | 分子名称: | Uncharacterized cupin protein, ZINC ION | | 著者 | Forouhar, F, Chen, Y, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Maglaqui, M, Wang, H, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-02-29 | | 公開日 | 2008-03-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal structure of a cupin protein (BF4112) from Bacteroides fragilis. Northeast Structural Genomics Consortium target BfR205.
To be Published
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1ELM
 | | CADMIUM-SUBSTITUTED BOVINE PACREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 5.5 AND 2 MM CHLORIDE IN MONOCLINIC CRYSTAL FORM. | | 分子名称: | CADMIUM ION, CARBOXYPEPTIDASE A | | 著者 | Jensen, F, Bukrinsky, T, Bjerrum, J, Larsen, S. | | 登録日 | 2000-03-14 | | 公開日 | 2002-06-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function
J.BIOL.INORG.CHEM., 7, 2002
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6G0E
 | | BRD4 (BD1) in complex with APSC-derived ligands | | 分子名称: | 4-[2-(4-cyclohexylpiperazin-4-ium-1-yl)-2-oxidanylidene-ethyl]sulfanyl-1-ethyl-quinolin-2-one, Bromodomain-containing protein 4, FORMIC ACID, ... | | 著者 | Pretzel, J, Humbeck, L. | | 登録日 | 2018-03-18 | | 公開日 | 2020-01-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.613 Å) | | 主引用文献 | Discovery of an Unexpected Similarity in Ligand Binding Between BRD4 and PPARgamma
Chemrxiv, 2019
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3D7T
 | | Structural basis for the recognition of c-Src by its inactivator Csk | | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, STAUROSPORINE, Tyrosine-protein kinase CSK | | 著者 | Levinson, N.M, Seeliger, M.A, Cole, P.A, Kuriyan, J. | | 登録日 | 2008-05-21 | | 公開日 | 2008-08-05 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.899 Å) | | 主引用文献 | Structural basis for the recognition of c-Src by its inactivator Csk.
Cell(Cambridge,Mass.), 134, 2008
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6G0G
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3CNG
 | | Crystal structure of NUDIX hydrolase from Nitrosomonas europaea | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Osipiuk, J, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-03-25 | | 公開日 | 2008-04-08 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray crystal structure of NUDIX hydrolase from Nitrosomonas europaea.
To be Published
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6G0W
 | | Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor MCD72 | | 分子名称: | 4-[3-[4-(4-fluorophenyl)piperidin-1-yl]carbonylphenoxy]benzamide, Poly [ADP-ribose] polymerase 14 | | 著者 | Karlberg, T, Thorsell, A.G, Holechek, J, Lease, R, Ferraris, D, Schuler, H. | | 登録日 | 2018-03-20 | | 公開日 | 2018-05-23 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14.
Bioorg. Med. Chem. Lett., 28, 2018
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3CNW
 | | Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196. | | 分子名称: | Protein XoxI | | 著者 | Kuzin, A.P, Abashidze, M, Seetharaman, J, Wang, H, Ciccosanti, C, Mao, L, Xiao, R, Nair, R, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-03-26 | | 公開日 | 2008-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196.
To Be Published
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3CGM
 | | Crystal structure of thermophilic SlyD | | 分子名称: | GLYCEROL, NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase, ... | | 著者 | Loew, C, Neumann, P, Stubbs, M.T, Balbach, J. | | 登録日 | 2008-03-06 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus
J.Mol.Biol., 398, 2010
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6G41
 | | Crystal structure of SeMet-labeled mavirus penton protein | | 分子名称: | Minor capsid protein | | 著者 | Born, D, Reuter, L, Meinhart, A, Reinstein, J. | | 登録日 | 2018-03-26 | | 公開日 | 2018-07-04 | | 最終更新日 | 2018-07-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Capsid protein structure, self-assembly, and processing reveal morphogenesis of the marine virophage mavirus.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6G4W
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State A | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2018-03-28 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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