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PDB: 42550 件

3FJF
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Crystal structure of C83T mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3F5M
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Crystal Structure of ATP-Bound Phosphofructokinase from Trypanosoma brucei
分子名称: 6-phospho-1-fructokinase (ATP-dependent phosphofructokinase), ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
著者McNae, I.W, Martinez-Oyanedel, J, Keillor, J.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D.
登録日2008-11-04
公開日2008-11-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of ATP-bound phosphofructokinase from Trypanosoma brucei reveals conformational transitions different from those of other phosphofructokinases.
J.Mol.Biol., 385, 2009
3F6J
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F17a-G lectin domain with bound GlcNAc(beta1-3)Gal
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-methyl beta-D-galactopyranoside, F17a-G
著者Buts, L, de Boer, A, Olsson, J.D.M, Jonckheere, W, De Kerpel, M, De Genst, E, Guerardel, Y, Willaert, R, Wyns, L, Wuhrer, M, Oscarson, S, De Greve, H, Bouckaert, J.
登録日2008-11-06
公開日2009-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli
Biology, 2, 2013
6BPE
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Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 6H1
分子名称: Monoclonal antibody 6H1 Fab heavy chain, Monoclonal antibody 6H1 Fab light chain, Reticulocyte binding protein 2, ...
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6FUJ
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Complement factor D in complex with the inhibitor N-(3'-(aminomethyl)-[1,1'-biphenyl]-3-yl)-3-methylbutanamide
分子名称: Complement factor D, ~{N}-[3-[3-(aminomethyl)phenyl]phenyl]-3-methyl-butanamide
著者Mac Sweeney, A, Ostermann, N, Vulpetti, A, Maibaum, J, Erbel, P, Lorthiois, E, Yoon, T, Randl, S, Ruedisser, S.
登録日2018-02-27
公開日2018-06-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D.
ACS Med Chem Lett, 9, 2018
1GHK
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SOLUTION STRUCTURE OF THE LIPOYL DOMAIN OF THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX FROM AZOTOBACTER VINELAND II, NMR, 25 STRUCTURES
分子名称: E2, THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX
著者Berg, A, Vervoort, J, De Kok, A.
登録日1996-01-16
公開日1997-01-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii.
J.Mol.Biol., 261, 1996
1GHJ
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SOLUTION STRUCTURE OF THE LIPOYL DOMAIN OF THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX FROM AZOTOBACTER VINELAND II, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: E2, THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX
著者Berg, A, Vervoort, J, De Kok, A.
登録日1996-01-16
公開日1997-01-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii.
J.Mol.Biol., 261, 1996
3FN3
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Dimeric Structure of PD-L1
分子名称: Programmed cell death 1 ligand 1
著者Chen, Y, Gao, F, Liu, P, Chu, F, Qi, J, Gao, G.F.
登録日2008-12-23
公開日2009-12-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A dimeric structure of PD-L1: functional units or evolutionary relics?
Protein Cell, 1, 2010
6C5W
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Crystal structure of the mitochondrial calcium uniporter
分子名称: CALCIUM ION, calcium uniporter, nanobody
著者Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L.
登録日2018-01-17
公開日2018-07-11
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (3.10010242 Å)
主引用文献X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
3FO5
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Human START domain of Acyl-coenzyme A thioesterase 11 (ACOT11)
分子名称: 3,3',3''-phosphanetriyltripropanoic acid, CHLORIDE ION, GLYCEROL, ...
著者Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van-Den-Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Shueler, H, Structural Genomics Consortium (SGC)
登録日2008-12-27
公開日2009-02-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparative structural analysis of lipid binding START domains.
Plos One, 6, 2011
3E0C
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BU of 3e0c by Molmil
Crystal Structure of DNA Damage-Binding protein 1(DDB1)
分子名称: DNA damage-binding protein 1
著者Amaya, M.F, Xu, L, Hao, H, Bountra, C, Wickstroem, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2008-07-31
公開日2008-09-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
3DXD
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BU of 3dxd by Molmil
Crystal structure of the intracellular domain of human APP (T668E mutant) in complex with Fe65-PTB2
分子名称: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
著者Radzimanowski, J, Sinning, I, Wild, K.
登録日2008-07-24
公開日2008-09-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
3E1E
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Crystal structure of a Thioesterase family protein from Silicibacter pomeroyi. NorthEast Structural Genomics target SiR180A
分子名称: Thioesterase family protein
著者Seetharaman, J, Abashidze, M, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2008-08-04
公開日2008-09-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a Thioesterase family protein from Silicibacter pomeroyi. NorthEast Structural Genomics target SiR180A
To be Published
6DRW
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BU of 6drw by Molmil
JAK2 JH1 in complex with JNJ-7706621 (Crystal Form 2)
分子名称: 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, Tyrosine-protein kinase JAK2
著者Puleo, D.E, Schlessinger, J.
登録日2018-06-13
公開日2018-07-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献JAK2 JH2 Binders
To Be Published
3DUZ
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BU of 3duz by Molmil
Crystal structure of the postfusion form of baculovirus fusion protein GP64
分子名称: MERCURY (II) ION, Major envelope glycoprotein
著者Kadlec, J, Loureiro, S, Abrescia, N.G.A, Jones, I.M, Stuart, D.I.
登録日2008-07-18
公開日2008-09-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines.
Nat.Struct.Mol.Biol., 15, 2008
6DV6
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Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG (residues 176-end) in the open gate state
分子名称: Protein InvG
著者Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
登録日2018-06-22
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
3E1R
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Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55
分子名称: Centrosomal protein of 55 kDa, Programmed cell death 6-interacting protein
著者Lee, H.H, Elia, N, Ghirlando, R, Lippincott-Schwartz, J, Hurley, J.H.
登録日2008-08-04
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55.
Science, 322, 2008
6DD5
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Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein
分子名称: GLYCEROL, MMB-1 Cas6 Fused to Maltose Binding Protein,CRISPR-associated endonuclease Cas1, SULFATE ION, ...
著者Stamos, J.L, Mohr, G, Silas, S, Makarova, K.S, Markham, L.M, Yao, J, Lucas-Elio, P, Sanchez-Amat, A, Fire, A.Z, Koonin, E.V, Lambowitz, A.M.
登録日2018-05-09
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition.
Mol. Cell, 72, 2018
6CAU
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BU of 6cau by Molmil
UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, UDP-N-acetylmuramate--L-alanine ligase
著者Horanyi, P.S, Abendroth, J, Lorimer, D.D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-01-31
公開日2018-03-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP
To be Published
6DDY
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Crystal structure of the double mutant (D52N/K359Q) of NT5C2-537X in the active state, Northeast Structural Genomics Target
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, PHOSPHATE ION
著者Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2018-05-10
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
Cancer Cell, 34, 2018
2K3Q
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Solution structure of the n-terminal domain (TUSP1-N) of the egg case silk from Nephila antipodiana
分子名称: TuSp1
著者Lin, Z, Huang, W, Fan, J, Yang, D.
登録日2008-05-15
公開日2009-06-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of eggcase silk protein and its implications for silk fiber formation
Proc.Natl.Acad.Sci.USA, 106, 2009
6DGP
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BU of 6dgp by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with TRAP220 Coactivator Peptide
分子名称: Peroxisome proliferator-activated receptor gamma, TRAP220 Coactivator Peptide (Mediator of RNA polymerase II transcription subunit 1)
著者Shang, J, Kojetin, D.J.
登録日2018-05-17
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with TRAP220 Coactivator Peptide
To Be Published
3E28
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H. influenzae beta-carbonic anhydrase, variant Y181F
分子名称: Carbonic anhydrase 2, SULFATE ION, ZINC ION
著者Rowlett, R.S, Lee, J.
登録日2008-08-05
公開日2009-06-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Allosteric site variants of Haemophilus influenzae beta-carbonic anhydrase.
Biochemistry, 48, 2009
5OGR
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BU of 5ogr by Molmil
Structure of cathepsin B1 from Schistosoma mansoni in complex with WRR286 inhibitor
分子名称: 3-[[N-[4-METHYL-PIPERAZINYL]CARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONIC ACID BENZYLOXY-AMIDE, ACETATE ION, Cathepsin B-like peptidase (C01 family)
著者Jilkova, A, Rezacova, P, Brynda, J, Mares, M.
登録日2017-07-13
公開日2018-11-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors.
Acs Infect Dis., 2020
6BIE
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BU of 6bie by Molmil
MISREADING CHAPERONE-SUBSTRATE COMPLEXES FROM RANDOM NOISE
分子名称: CHLORIDE ION, IMIDAZOLE, MAGNESIUM ION, ...
著者WANG, J.
登録日2017-11-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Misreading chaperone-substrate complexes from random noise.
Nat. Struct. Mol. Biol., 25, 2018

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