6DRW

JAK2 JH1 in complex with JNJ-7706621 (Crystal Form 2)

Summary for 6DRW

• Entry DOI: 10.2210/pdb6drw/pdb
• Descriptor: Tyrosine-protein kinase JAK2, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide (3 entities in total)
• Functional Keywords: kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 37792.76

Authors

Puleo, D.E.,Schlessinger, J. (deposition date: 2018-06-13, release date: 2018-07-18, Last modification date: 2023-11-15)

• Primary citation: Puleo, D.E.,Schlessinger, J.; JAK2 JH2 Binders; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.303 Å)