6FIV
 
 | | STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR | | 分子名称: | RETROPEPSIN, SULFATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | | 著者 | Li, M, Lee, T, Morris, G, Laco, G, Wong, C, Olson, A, Elder, J, Wlodawer, A, Gustchina, A. | | 登録日 | 1998-12-02 | | 公開日 | 1998-12-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease
Proteins, 38, 2000
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3FKS
 | | Yeast F1 ATPase in the absence of bound nucleotides | | 分子名称: | ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ... | | 著者 | Kabaleeswaran, V, Symersky, J, Shen, H, Walker, J.E, Leslie, A.G.W, Mueller, D.M. | | 登録日 | 2008-12-17 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.587 Å) | | 主引用文献 | Asymmetric structure of the yeast f1 ATPase in the absence of bound nucleotides.
J.Biol.Chem., 284, 2009
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3F6D
 | | Crystal Structure of a Genetically Modified Delta Class GST (adGSTD4-4) from Anopheles dirus, F123A, in Complex with S-Hexyl Glutathione | | 分子名称: | Glutathione transferase GST1-4, S-HEXYLGLUTATHIONE | | 著者 | Wongsantichon, J, Robinson, R.C, Ketterman, A.J. | | 登録日 | 2008-11-05 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural contributions of delta class glutathione transferase active-site residues to catalysis
Biochem.J., 428, 2010
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6FKE
 | | Structure of 3' phosphatase NExo (D146N) from Neisseria bound to product DNA hairpin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*A)-3'), Exodeoxyribonuclease III, ... | | 著者 | Silhan, J, Zhao, Q, Boura, E, Thomson, H, Foster, A, Tang, C.M, Freemont, P.S, Baldwin, G.S. | | 登録日 | 2018-01-23 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | | 主引用文献 | Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res., 46, 2018
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3F6X
 | | c-Src kinase domain in complex with small molecule inhibitor | | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile | | 著者 | Seeliger, M.A, Statsuk, A.V, Maly, D.J, Patrick, P.Z, Kuriyan, J, Shokat, K.M. | | 登録日 | 2008-11-06 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Tuning a three-component reaction for trapping kinase substrate complexes.
J.Am.Chem.Soc., 130, 2008
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6B8X
 | | Multiconformer model of apo WT PTP1B with glycerol at 278 K | | 分子名称: | GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. | | 登録日 | 2017-10-09 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Elife, 7, 2018
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3F7J
 | | B.subtilis YvgN | | 分子名称: | NITRATE ION, POTASSIUM ION, YvgN protein | | 著者 | Zhou, Y.F, Lei, J, Liang, Y.H, Su, X.-D. | | 登録日 | 2008-11-09 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis
Protein Sci., 18, 2009
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6FB7
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6FCH
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5NV9
 | | Substrate-bound outward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+-site | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, N-acetyl-beta-neuraminic acid, PHOSPHATE ION, ... | | 著者 | Wahlgren, W.Y, North, R.A, Dunevall, E, Paz, A, Goyal, P, Bisignano, P, Grabe, M, Dobson, R, Abramson, J, Ramaswamy, S, Friemann, R. | | 登録日 | 2017-05-03 | | 公開日 | 2018-04-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site.
Nat Commun, 9, 2018
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5NVA
 | | Substrate-bound outward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+-site | | 分子名称: | N-acetyl-beta-neuraminic acid, Putative sodium:solute symporter, SODIUM ION | | 著者 | Wahlgren, W.Y, North, R.A, Dunevall, E, Goyal, P, Grabe, M, Dobson, R, Abramson, J, Ramaswamy, S, Friemann, R. | | 登録日 | 2017-05-03 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site.
Nat Commun, 9, 2018
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3F5F
 | | Crystal structure of heparan sulfate 2-O-sulfotransferase from gallus gallus as a maltose binding protein fusion. | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Maltose-binding periplasmic protein, Heparan sulfate 2-O-sulfotransferase 1, ... | | 著者 | Bethea, H.N, Xu, D, Liu, J, Pedersen, L.C. | | 登録日 | 2008-11-03 | | 公開日 | 2008-12-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis.
Proc.Natl.Acad.Sci.USA, 105, 2008
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3F65
 | | The F4 fimbrial chaperone FaeE does not self-cap its interactive surfaces | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Chaperone protein faeE, PHOSPHATE ION | | 著者 | Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J. | | 登録日 | 2008-11-05 | | 公開日 | 2009-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
Acta Crystallogr.,Sect.D, 65, 2009
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6FEQ
 | | Structure of inhibitor-bound ABCG2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | | 著者 | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. | | 登録日 | 2018-01-03 | | 公開日 | 2018-04-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat. Struct. Mol. Biol., 25, 2018
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3COO
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5NSC
 | | Fc DEKK heterodimer variant | | 分子名称: | Fc-III peptide, GLYCEROL, Putative uncharacterized protein DKFZp686C11235, ... | | 著者 | De Nardis, C, Hendriks, L.J.A, Poirier, E, Arvinte, T, Gros, P, Bakker, A.B.H, de Kruif, J. | | 登録日 | 2017-04-26 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1.
J. Biol. Chem., 292, 2017
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3COX
 | | CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES | | 分子名称: | CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Vrielink, A, Li, J, Brick, P, Blow, D.M. | | 登録日 | 1993-06-14 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.
Biochemistry, 32, 1993
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6FJV
 | | Rpn11 homolog from Caldiarchaeum Subterraneum, truncated | | 分子名称: | 26S proteasome regulatory subunit N11-like protein, SULFATE ION | | 著者 | Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. | | 登録日 | 2018-01-23 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system.
Nat Commun, 9, 2018
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3CFS
 | | Structural basis of the interaction of RbAp46/RbAp48 with histone H4 | | 分子名称: | ARSENIC, Histone H4, Histone-binding protein RBBP7 | | 著者 | Murzina, N.V, Pei, X.-Y, Pratap, J.V, Sparkes, M, Vicente-Garcia, J, Ben-Shahar, T.R, Verreault, A, Luisi, B.F, Laue, E.D. | | 登録日 | 2008-03-04 | | 公開日 | 2008-06-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46.
Structure, 16, 2008
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6FHL
 | | Cryo-EM structure of F-actin in complex with ADP-Pi | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | 登録日 | 2018-01-15 | | 公開日 | 2018-06-13 | | 最終更新日 | 2018-08-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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6FKI
 | | Chloroplast F1Fo conformation 3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | | 著者 | Hahn, A, Vonck, J, Mills, D.J, Meier, T, Kuehlbrandt, W. | | 登録日 | 2018-01-24 | | 公開日 | 2018-05-23 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure, mechanism, and regulation of the chloroplast ATP synthase.
Science, 360, 2018
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3CS3
 | | Crystal structure of sugar-binding transcriptional regulator (LacI family) from Enterococcus faecalis | | 分子名称: | GLYCEROL, SULFATE ION, Sugar-binding transcriptional regulator, ... | | 著者 | Patskovsky, Y, Romero, R, Freeman, J, Iizuka, M, Groshong, C, Smith, D, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-04-08 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of sugar-binding transcriptional regulator (LacI family) from Enterococcus faecalis.
To be Published
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6FJE
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6B73
 | | Crystal Structure of a nanobody-stabilized active state of the kappa-opioid receptor | | 分子名称: | CHOLESTEROL, N-[(5alpha,6beta)-17-(cyclopropylmethyl)-3-hydroxy-7,8-didehydro-4,5-epoxymorphinan-6-yl]-3-iodobenzamide, Nanobody, ... | | 著者 | Che, T, Majumdar, S, Zaidi, S.A, Kormos, C, McCorvy, J.D, Wang, S, Mosier, P.D, Uprety, R, Vardy, E, Krumm, B.E, Han, G.W, Lee, M.Y, Pardon, E, Steyaert, J, Huang, X.P, Strachan, R.T, Tribo, A.R, Pasternak, G.W, Carroll, I.F, Stevens, R.C, Cherezov, V, Katritch, V, Wacker, D, Roth, B.L. | | 登録日 | 2017-10-03 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Cell, 172, 2018
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6FKO
 | | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, hadacidin at 2.1 Angstrom resolution | | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase, ... | | 著者 | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | | 登録日 | 2018-01-24 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, HAdacidin at 2.1 Angstrom resolution
To Be Published
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