1DQA
 
 | | COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG, COA, AND NADP+ | | Descriptor: | 3-HYDROXY-3-METHYL-GLUTARIC ACID, COENZYME A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Istvan, E.S, Palnitkar, M, Buchanan, S.K, Deisenhofer, J. | | Deposit date: | 1999-12-30 | | Release date: | 2000-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.
EMBO J., 19, 2000
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1DQ9
 | | COMPLEX OF CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG-COA | | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, PROTEIN (HMG-COA REDUCTASE) | | Authors: | Istvan, E.S, Palnitkar, M, Buchanan, S.K, Deisenhofer, J. | | Deposit date: | 1999-12-30 | | Release date: | 2000-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.
EMBO J., 19, 2000
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1DQ8
 | | COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG AND COA | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-HYDROXY-3-METHYL-GLUTARIC ACID, COENZYME A, ... | | Authors: | Istvan, E.S, Palnitkar, M, Buchanan, S.K, Deisenhofer, J. | | Deposit date: | 1999-12-30 | | Release date: | 2000-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.
EMBO J., 19, 2000
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1HWI
 | | COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH FLUVASTATIN | | Descriptor: | (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE | | Authors: | Istvan, E.S, Deisenhofer, J. | | Deposit date: | 2001-01-09 | | Release date: | 2001-05-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
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1HW9
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1HW8
 | | COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH COMPACTIN (ALSO KNOWN AS MEVASTATIN) | | Descriptor: | (3R,5R)-3,5-dihydroxy-7-[(1S,2S,8S,8aR)-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]h eptanoic acid, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE | | Authors: | Istvan, E.S, Deisenhofer, J. | | Deposit date: | 2001-01-09 | | Release date: | 2001-05-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
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1HWJ
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1HWK
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1HWL
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3S5M
 | | Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum | | Descriptor: | Falcilysin, MAGNESIUM ION, ZINC ION | | Authors: | Morgunova, E, Ponpuak, M, Istvan, E, Popov, A, Goldberg, D, Eneqvist, T. | | Deposit date: | 2011-05-23 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structures of falcilysin, a M16 metalloprotease from
the malaria parasite Plasmodium falciparum
To be Published
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3S5H
 | | Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum | | Descriptor: | COBALT (II) ION, Falcilysin | | Authors: | Morgunova, E, Ponpuak, M, Istvan, E, Popov, A, Goldberg, D, Eneqvist, T. | | Deposit date: | 2011-05-23 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.603 Å) | | Cite: | Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum
To be Published
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3S5I
 | | Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum | | Descriptor: | Falcilysin | | Authors: | Morgunova, E, Ponpuak, M, Istvan, E, Popov, A, Goldberg, D, Eneqvist, T. | | Deposit date: | 2011-05-23 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.743 Å) | | Cite: | Crystal structures of falcilysin, a M16 metalloprotease from
the malaria parasite Plasmodium falciparum
To be Published
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3S5K
 | | Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum | | Descriptor: | Falcilysin, ZINC ION | | Authors: | Morgunova, E, Ponpuak, M, Istvan, E, Popov, A, Goldberg, D, Eneqvist, T. | | Deposit date: | 2011-05-23 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structures of falcilysin, a M16 metalloprotease from
the malaria parasite Plasmodium falciparum
To be Published
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