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PDB: 127 件

3CJ0
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
分子名称: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
1HDD
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BU of 1hdd by Molmil
CRYSTAL STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8 ANGSTROMS RESOLUTION: A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS
分子名称: DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*C P*CP*TP*AP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN)
著者Kissinger, C.R, Liu, B, Martin-Blanco, E, Kornberg, T.B, Pabo, C.O.
登録日1991-09-16
公開日1992-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 63, 1990
1FXD
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BU of 1fxd by Molmil
REFINED CRYSTAL STRUCTURE OF FERREDOXIN II FROM DESULFOVIBRIO GIGAS AT 1.7 ANGSTROMS
分子名称: FE3-S4 CLUSTER, FERREDOXIN II
著者Kissinger, C.R, Sieker, L.C, Adman, E.T, Jensen, L.H.
登録日1991-04-08
公開日1993-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Refined crystal structure of ferredoxin II from Desulfovibrio gigas at 1.7 A.
J.Mol.Biol., 219, 1991
1U7T
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BU of 1u7t by Molmil
Crystal Structure of ABAD/HSD10 with a Bound Inhibitor
分子名称: 1-AZEPAN-1-YL-2-PHENYL-2-(4-THIOXO-1,4-DIHYDRO-PYRAZOLO[3,4-D]PYRIMIDIN-5-YL)ETHANONE ADDUCT, 3-hydroxyacyl-CoA dehydrogenase type II, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kissinger, C.R, Rejto, P.A, Pelletier, L.A, Showalter, R.E, Villafranca, J.E.
登録日2004-08-04
公開日2004-10-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics
J.Mol.Biol., 342, 2004
4J03
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BU of 4j03 by Molmil
Crystal structure of human soluble epoxide hydrolase complexed with fulvestrant
分子名称: (7beta,9beta,13alpha,17beta)-7-{9-[(R)-(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ...
著者Morisseau, C, Pakhomova, S, Hwang, S.H, Newcomer, M.E, Hammock, B.D.
登録日2013-01-30
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides.
Bioorg.Med.Chem.Lett., 23, 2013
6HUD
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BU of 6hud by Molmil
Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient.
分子名称: Monoclonal immunoglobulin light chains (LC)
著者Paissoni, C, Camilloni, C.
登録日2018-10-06
公開日2019-03-27
最終更新日2019-04-03
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
Nat Commun, 10, 2019
6GHT
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BU of 6ght by Molmil
HtxB D206A protein variant from Pseudomonas stutzeri in complex with hypophosphite to 1.12 A resolution
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, FORMIC ACID, ...
著者Bisson, C, Robertson, A.J, Hitchcock, A, Adams, N.B.
登録日2018-05-09
公開日2019-05-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Phosphite binding by the HtxB periplasmic binding protein depends on the protonation state of the ligand.
Sci Rep, 9, 2019
5T83
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Structure of a guanidine-I riboswitch from S. acidophilus
分子名称: GUANIDINE, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ...
著者Reiss, C.W, Xiong, Y, Strobel, S.A.
登録日2016-09-06
公開日2017-01-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural Basis for Ligand Binding to the Guanidine-I Riboswitch.
Structure, 25, 2017
6EMN
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BU of 6emn by Molmil
HtxB from Pseudomonas stutzeri in complex with phosphite to 1.25 A resolution
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Probable phosphite transport system-binding protein HtxB, ...
著者Bisson, C, Robertson, A.J, Hitchcock, A, Adams, N.B.
登録日2017-10-03
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Phosphite binding by the HtxB periplasmic binding protein depends on the protonation state of the ligand.
Sci Rep, 9, 2019
7NQG
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BU of 7nqg by Molmil
The structure of the SBP TarP_Rhp in complex with 4-hydroxyphenylacetate
分子名称: 1,2-ETHANEDIOL, 4-HYDROXYPHENYLACETATE, PHOSPHATE ION, ...
著者Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J.
登録日2021-03-01
公開日2021-10-06
最終更新日2022-01-26
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
7NR2
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BU of 7nr2 by Molmil
The structure of the SBP TarP_Sse in complex with coumarate
分子名称: 4'-HYDROXYCINNAMIC ACID, SULFATE ION, TRAP dicarboxylate transporter, ...
著者Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J.
登録日2021-03-02
公開日2021-10-06
最終更新日2022-01-26
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
7NRR
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BU of 7nrr by Molmil
The structure of the SBP TarP_Csal in complex with caffeate
分子名称: CAFFEIC ACID, MAGNESIUM ION, TRAP dicarboxylate transporter-DctP subunit
著者Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J.
登録日2021-03-04
公開日2021-10-06
最終更新日2022-01-26
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
7NRA
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BU of 7nra by Molmil
The structure of the SBP TarP_Sse in complex with cinnamate
分子名称: HYDROCINNAMIC ACID, TRAP dicarboxylate transporter, DctP subunit
著者Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J.
登録日2021-03-03
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
7NSW
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BU of 7nsw by Molmil
The structure of the SBP TarP_Csal in complex with coumarate
分子名称: 1,2-ETHANEDIOL, 4'-HYDROXYCINNAMIC ACID, MAGNESIUM ION, ...
著者Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J.
登録日2021-03-08
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
7NTD
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BU of 7ntd by Molmil
The structure of the SBP TarP_Csal in complex with ferulate
分子名称: 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, MAGNESIUM ION, SULFATE ION, ...
著者Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J.
登録日2021-03-09
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
7NTE
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BU of 7nte by Molmil
The structure of an open conformation of the SBP TarP_Csal
分子名称: MAGNESIUM ION, TRAP dicarboxylate transporter-DctP subunit
著者Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J.
登録日2021-03-09
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
6GHQ
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BU of 6ghq by Molmil
HtxB D206N protein variant from Pseudomonas stutzeri in a partially open conformation to 1.53 A resolution
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, ...
著者Bisson, C, Robertson, A.J, Hitchcock, A, Adams, N.B.
登録日2018-05-08
公開日2019-05-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Phosphite binding by the HtxB periplasmic binding protein depends on the protonation state of the ligand.
Sci Rep, 9, 2019
6YS9
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T_926 truncate of ChlH from Thermosynechococcus elongatus at 1.64 A resolution
分子名称: Magnesium-protoporphyrin methyltransferase, POTASSIUM ION
著者Bisson, C, Hunter, C.N.
登録日2020-04-21
公開日2020-12-09
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The active site of magnesium chelatase.
Nat.Plants, 6, 2020
6YSG
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BU of 6ysg by Molmil
Magnesium chelatase H subunit (ChlH) from Synechocystis sp.PCC6803 to 2.54 A resolution
分子名称: CITRIC ACID, Mg-chelatase subunit ChlH
著者Bisson, C, Hunter, C.N.
登録日2020-04-22
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献The active site of magnesium chelatase.
Nat.Plants, 6, 2020
6YT0
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BU of 6yt0 by Molmil
Magnesium chelatase H subunit (ChlH) E660D variant from Synechocystis sp.PCC6803
分子名称: Mg-chelatase subunit ChlH
著者Bisson, C, Hunter, C.N.
登録日2020-04-23
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The active site of magnesium chelatase.
Nat.Plants, 6, 2020
6YTJ
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BU of 6ytj by Molmil
Magnesium chelatase H subunit (ChlH) E625K variant from Synechocystis sp.PCC6803
分子名称: Mg-chelatase subunit ChlH
著者Bisson, C, Hunter, C.N.
登録日2020-04-24
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献The active site of magnesium chelatase.
Nat.Plants, 6, 2020
6YTN
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BU of 6ytn by Molmil
Magnesium chelatase H subunit (ChlH) E660W variant from Synechocystis sp.PCC6803
分子名称: Mg-chelatase subunit ChlH
著者Bisson, C, Hunter, C.N.
登録日2020-04-24
公開日2020-12-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The active site of magnesium chelatase.
Nat.Plants, 6, 2020
5O2K
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BU of 5o2k by Molmil
Native apo-structure of Pseudomonas stutzeri PtxB to 2.1 A resolution
分子名称: Probable phosphite transport system-binding protein PtxB
著者Bisson, C, Hitchcock, A.
登録日2017-05-21
公開日2017-12-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The molecular basis of phosphite and hypophosphite recognition by ABC-transporters.
Nat Commun, 8, 2017

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