6HUD

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient.

Summary for 6HUD

Entry DOI	10.2210/pdb6hud/pdb
EMDB information	0274
Descriptor	Monoclonal immunoglobulin light chains (LC) (1 entity in total)
Functional Keywords	immunoglobulin light chains; amyloid cardiomyopathy; ex-vivo cryo-em; helical reconstruction;, protein fibril
Biological source	Homo sapiens
Total number of polymer chains	5
Total formula weight	73104.32
Authors	Paissoni, C.,Camilloni, C. (deposition date: 2018-10-06, release date: 2019-03-27, Last modification date: 2019-04-03)
Primary citation	Swuec, P.,Lavatelli, F.,Tasaki, M.,Paissoni, C.,Rognoni, P.,Maritan, M.,Brambilla, F.,Milani, P.,Mauri, P.,Camilloni, C.,Palladini, G.,Merlini, G.,Ricagno, S.,Bolognesi, M. Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient. Nat Commun, 10:1269-1269, 2019 Cited by PubMed: 30894521 DOI: 10.1038/s41467-019-09133-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation