4GTY
| Crystal structure of mouse Enpp1 in complex with GMP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-08-29 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109, 2012
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5X2G
| Crystal structure of Campylobacter jejuni Cas9 in complex with sgRNA and target DNA (AGAAACC PAM) | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, Non-target DNA strand, ... | Authors: | Yamada, M, Watanabe, Y, Hirano, H, Nakane, T, Ishitani, R, Nishimasu, H, Nureki, O. | Deposit date: | 2017-01-31 | Release date: | 2017-03-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems Mol. Cell, 65, 2017
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5X2H
| Crystal structure of Campylobacter jejuni Cas9 in complex with sgRNA and target DNA (AGAAACA PAM) | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, Non-target DNA strand, ... | Authors: | Yamada, M, Watanabe, Y, Hirano, H, Nakane, T, Ishitani, R, Nishimasu, H, Nureki, O. | Deposit date: | 2017-01-31 | Release date: | 2017-03-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems Mol. Cell, 65, 2017
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4GTX
| Crystal structure of mouse Enpp1 in complex with TMP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-08-29 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109, 2012
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5XUT
| Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TCTA PAM) | Descriptor: | 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*TP*CP*TP*A)-3'), ... | Authors: | Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2017-06-26 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67, 2017
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5XUS
| Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TTTA PAM) | Descriptor: | 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*A)-3'), ... | Authors: | Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2017-06-26 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67, 2017
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5XUU
| Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TCCA PAM) | Descriptor: | 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*TP*CP*CP*A)-3'), ... | Authors: | Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2017-06-26 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67, 2017
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4IKX
| Crystal structure of peptide transporter POT (E310Q mutant) | Descriptor: | Di-tripeptide ABC transporter (Permease), OLEIC ACID, SULFATE ION | Authors: | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | Deposit date: | 2012-12-28 | Release date: | 2013-07-10 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
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5Y50
| Crystal structure of eukaryotic MATE transporter AtDTX14 | Descriptor: | Protein DETOXIFICATION 14 | Authors: | Miyauchi, H, Kusakizako, T, Nishizawa, T, Ishitani, R, Nureki, O. | Deposit date: | 2017-08-06 | Release date: | 2017-12-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for xenobiotic extrusion by eukaryotic MATE transporter Nat Commun, 8, 2017
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4IKV
| Crystal structure of peptide transporter POT | Descriptor: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Di-tripeptide ABC transporter (Permease), OLEIC ACID, ... | Authors: | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | Deposit date: | 2012-12-28 | Release date: | 2013-07-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IKZ
| Crystal structure of peptide transporter POT (E310Q mutant) in complex with alafosfalin | Descriptor: | Di-tripeptide ABC transporter (Permease), N-[(1R)-1-phosphonoethyl]-L-alaninamide, SULFATE ION | Authors: | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | Deposit date: | 2012-12-28 | Release date: | 2013-07-10 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
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3X3B
| Crystal structure of the light-driven sodium pump KR2 in acidic state | Descriptor: | DI(HYDROXYETHYL)ETHER, OLEIC ACID, RETINAL, ... | Authors: | Kato, H.E, Inoue, K, Abe-Yoshizumi, R, Kato, Y, Ono, H, Konno, M, Ishizuka, T, Hoque, M.R, Hososhima, S, Kunitomo, H, Ito, J, Yoshizawa, S, Yamashita, K, Takemoto, M, Nishizawa, T, Taniguchi, R, Kogure, K, Maturana, A.D, Iino, Y, Yawo, H, Ishitani, R, Kandori, H, Nureki, O. | Deposit date: | 2015-01-18 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for Na(+) transport mechanism by a light-driven Na(+) pump Nature, 521, 2015
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3X3C
| Crystal structure of the light-driven sodium pump KR2 in neutral state | Descriptor: | OLEIC ACID, RETINAL, Sodium pumping rhodopsin | Authors: | Kato, H.E, Inoue, K, Abe-Yoshizumi, R, Kato, Y, Ono, H, Konno, M, Ishizuka, T, Hoque, M.R, Hososhima, S, Kunitomo, H, Ito, J, Yoshizawa, S, Yamashita, K, Takemoto, M, Nishizawa, T, Taniguchi, R, Kogure, K, Maturana, A.D, Iino, Y, Yawo, H, Ishitani, R, Kandori, H, Nureki, O. | Deposit date: | 2015-01-18 | Release date: | 2015-04-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for Na(+) transport mechanism by a light-driven Na(+) pump Nature, 521, 2015
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4KPP
| Crystal Structure of H+/Ca2+ Exchanger CAX | Descriptor: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, OLEIC ACID, ... | Authors: | Nishizawa, T, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-14 | Release date: | 2013-06-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the counter-transport mechanism of a H+/Ca2+ exchanger. Science, 341, 2013
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3VWA
| Crystal structure of Cex1p | Descriptor: | Cytoplasmic export protein 1 | Authors: | Nozawa, K, Ishitani, R, Nureki, O. | Deposit date: | 2012-08-13 | Release date: | 2013-06-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm Nucleic Acids Res., 41, 2013
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5AWW
| Precise Resting State of Thermus thermophilus SecYEG | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Protein translocase subunit SecE, Protein translocase subunit SecY, ... | Authors: | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | Deposit date: | 2015-07-10 | Release date: | 2015-11-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.724 Å) | Cite: | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State. Cell Rep, 13, 2015
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4YBG
| Crystal structure of the MAEL domain of Drosophila melanogaster Maelstrom | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Protein maelstrom, ... | Authors: | Matsumoto, N, Ishitani, R, Nishimasu, H, Nureki, O. | Deposit date: | 2015-02-18 | Release date: | 2015-04-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom Cell Rep, 11, 2015
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5B43
| Crystal structure of Acidaminococcus sp. Cpf1 in complex with crRNA and target DNA | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cpf1, DNA (34-MER), ... | Authors: | Yamano, T, Nishimasu, H, Hirano, H, Nakane, T, Ishitani, R, Nureki, O. | Deposit date: | 2016-03-30 | Release date: | 2016-05-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA Cell, 165, 2016
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5AXW
| Crystal structure of Staphylococcus aureus Cas9 in complex with sgRNA and target DNA (TTGGGT PAM) | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, DNA (28-MER), ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2015-08-01 | Release date: | 2015-09-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of Staphylococcus aureus Cas9. Cell, 162, 2015
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5CZZ
| Crystal structure of Staphylococcus aureus Cas9 in complex with sgRNA and target DNA (TTGAAT PAM) | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, DNA (28-MER), ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2015-08-01 | Release date: | 2015-09-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Staphylococcus aureus Cas9. Cell, 162, 2015
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3WTR
| Crystal structure of E. coli YfcM bound to Co(II) | Descriptor: | COBALT (II) ION, Uncharacterized protein | Authors: | Kobayashi, K, Ishii, R, Ishitani, R, Nureki, O. | Deposit date: | 2014-04-19 | Release date: | 2015-04-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation Nucleic Acids Res., 42, 2014
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3WUH
| Qri7 and AMP complex | Descriptor: | ADENOSINE MONOPHOSPHATE, ZINC ION, tRNA N6-adenosine threonylcarbamoyltransferase, ... | Authors: | Tominaga, T, Kobayashi, K, Ishii, R, Ishitani, R, Nureki, O. | Deposit date: | 2014-04-24 | Release date: | 2014-09-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.937 Å) | Cite: | Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP ACTA CRYSTALLOGR.,SECT.F, 70, 2014
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5CH4
| Peptide-Bound State of Thermus thermophilus SecYEG | Descriptor: | Protein translocase subunit SecE, Protein translocase subunit SecY, Putative preprotein translocase, ... | Authors: | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | Deposit date: | 2015-07-10 | Release date: | 2015-11-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.64 Å) | Cite: | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State. Cell Rep, 13, 2015
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3VUY
| Crystal structure of A20 ZF7 in complex with linear tetraubiquitin | Descriptor: | POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-07-09 | Release date: | 2013-02-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
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3VUW
| Crystal structure of A20 ZF7 in complex with linear ubiquitin, form I | Descriptor: | POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-07-09 | Release date: | 2013-02-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
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