3NH8
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![BU of 3nh8 by Molmil](/molmil-images/mine/3nh8) | Crystal structure of murine aminoacylase 3 in complex with N-acetyl-S-1,2-dichlorovinyl-L-cysteine | Descriptor: | Aspartoacylase-2, CHLORIDE ION, N-acetyl-S-[(1S)-1,2-dichloroethyl]-L-cysteine, ... | Authors: | Hsieh, J.M, Tsirulnikov, K, Sawaya, M.R, Magilnick, N, Abuladze, N, Kurtz, I, Abramson, J, Pushkin, A. | Deposit date: | 2010-06-14 | Release date: | 2010-10-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Structures of aminoacylase 3 in complex with acetylated substrates. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NH5
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![BU of 3nh5 by Molmil](/molmil-images/mine/3nh5) | Crystal structure of E177A-mutant murine aminoacylase 3 | Descriptor: | ACETATE ION, Aspartoacylase-2, CHLORIDE ION, ... | Authors: | Hsieh, J.M, Tsirulnikov, K, Sawaya, M.R, Magilnick, N, Abuladze, N, Kurtz, I, Abramson, J, Pushkin, A. | Deposit date: | 2010-06-14 | Release date: | 2010-10-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.094 Å) | Cite: | Structures of aminoacylase 3 in complex with acetylated substrates. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NJZ
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![BU of 3njz by Molmil](/molmil-images/mine/3njz) | Crystal Structure of Salicylate 1,2-dioxygenase from Pseudoaminobacter salicylatoxidans Adducts with salicylate | Descriptor: | 2-HYDROXYBENZOIC ACID, FE (II) ION, GLYCEROL, ... | Authors: | Ferraroni, M, Briganti, F, Matera, I. | Deposit date: | 2010-06-18 | Release date: | 2011-07-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of salicylate 1,2-dioxygenase-substrates adducts: A step towards the comprehension of the structural basis for substrate selection in class III ring cleaving dioxygenases. J.Struct.Biol., 177, 2012
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3N8E
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![BU of 3n8e by Molmil](/molmil-images/mine/3n8e) | Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin) | Descriptor: | Stress-70 protein, mitochondrial | Authors: | Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, van der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-05-28 | Release date: | 2010-06-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin) To be published
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3NAI
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![BU of 3nai by Molmil](/molmil-images/mine/3nai) | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | Descriptor: | 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. | Deposit date: | 2010-06-02 | Release date: | 2011-06-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
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3NC5
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![BU of 3nc5 by Molmil](/molmil-images/mine/3nc5) | CYP134A1 structure with an open substrate binding loop | Descriptor: | Cytochrome P450 cypX, GLYCEROL, MAGNESIUM ION, ... | Authors: | Cryle, M.J, Schlichting, I. | Deposit date: | 2010-06-04 | Release date: | 2010-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry, 49, 2010
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3NML
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![BU of 3nml by Molmil](/molmil-images/mine/3nml) | Sperm whale myoglobin mutant H64W carbonmonoxy-form | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Birukou, I, Soman, J, Olson, J.S. | Deposit date: | 2010-06-22 | Release date: | 2010-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Blocking the gate to ligand entry in human hemoglobin. J.Biol.Chem., 286, 2011
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3N50
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![BU of 3n50 by Molmil](/molmil-images/mine/3n50) | Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains | Descriptor: | Transcription factor COE3 | Authors: | Lehtio, L, Siponen, M.I, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schuler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-05-24 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
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3NL1
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![BU of 3nl1 by Molmil](/molmil-images/mine/3nl1) | Crystal Structure of Salicylate 1,2-dioxygenase from Pseudoaminobacter salicylatoxidans Adducts with gentisate | Descriptor: | 2,5-dihydroxybenzoic acid, FE (II) ION, GLYCEROL, ... | Authors: | Ferraroni, M, Briganti, F, Matera, I. | Deposit date: | 2010-06-21 | Release date: | 2011-07-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.155 Å) | Cite: | Crystal structures of salicylate 1,2-dioxygenase-substrates adducts: A step towards the comprehension of the structural basis for substrate selection in class III ring cleaving dioxygenases. J.Struct.Biol., 177, 2012
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3NMM
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![BU of 3nmm by Molmil](/molmil-images/mine/3nmm) | Human Hemoglobin A mutant alpha H58W deoxy-form | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Birukou, I, Soman, J, Olson, J.S. | Deposit date: | 2010-06-22 | Release date: | 2010-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Blocking the gate to ligand entry in human hemoglobin. J.Biol.Chem., 286, 2011
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3NES
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![BU of 3nes by Molmil](/molmil-images/mine/3nes) | V30M mutant human transthyretin (TTR) complexed with GC-1 (V30M:GC-1) | Descriptor: | GLYCEROL, Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | Authors: | Trivella, D.B.B, Polikarpov, I. | Deposit date: | 2010-06-09 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition. J.Struct.Biol., 173, 2011
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3NKT
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![BU of 3nkt by Molmil](/molmil-images/mine/3nkt) | Crystal Structure of Salicylate 1,2-dioxygenase from Pseudoaminobacter salicylatoxidans Adducts with naphthoate | Descriptor: | 1-hydroxynaphthalene-2-carboxylic acid, FE (II) ION, GLYCEROL, ... | Authors: | Ferraroni, M, Briganti, F, Matera, I. | Deposit date: | 2010-06-21 | Release date: | 2011-07-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures of salicylate 1,2-dioxygenase-substrates adducts: A step towards the comprehension of the structural basis for substrate selection in class III ring cleaving dioxygenases. J.Struct.Biol., 177, 2012
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3N7O
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![BU of 3n7o by Molmil](/molmil-images/mine/3n7o) | X-ray structure of human chymase in complex with small molecule inhibitor. | Descriptor: | (S)-[(1S)-1-(5-chloro-1-benzothiophen-3-yl)-2-{[(E)-2-(3,4-difluorophenyl)ethenyl]amino}-2-oxoethyl]methylphosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, ... | Authors: | Abad, M.C, Kervinen, J, Crysler, C, Bayoumy, S, Spurlino, J, Deckman, I, Greco, M.N, Maryanoff, B.E, Degaravilla, L. | Deposit date: | 2010-05-27 | Release date: | 2010-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Potency variation of small-molecule chymase inhibitors across species. Biochem. Pharmacol., 80, 2010
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3NEO
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![BU of 3neo by Molmil](/molmil-images/mine/3neo) | |
3NC6
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![BU of 3nc6 by Molmil](/molmil-images/mine/3nc6) | CYP134A1 1-phenylimidazole bound structure | Descriptor: | 1-phenyl-1H-imidazole, Cytochrome P450 cypX, MAGNESIUM ION, ... | Authors: | Cryle, M.J, Schlichting, I. | Deposit date: | 2010-06-04 | Release date: | 2010-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry, 49, 2010
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3NFZ
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![BU of 3nfz by Molmil](/molmil-images/mine/3nfz) | Crystal structure of murine aminoacylase 3 in complex with N-acetyl-L-tyrosine | Descriptor: | Aspartoacylase-2, CHLORIDE ION, N-acetyl-L-tyrosine, ... | Authors: | Hsieh, J.M, Tsirulnikov, K, Sawaya, M.R, Magilnick, N, Abuladze, N, Kurtz, I, Abramson, J, Pushkin, A. | Deposit date: | 2010-06-10 | Release date: | 2010-10-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.147 Å) | Cite: | Structures of aminoacylase 3 in complex with acetylated substrates. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NC3
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![BU of 3nc3 by Molmil](/molmil-images/mine/3nc3) | CYP134A1 structure with a closed substrate binding loop | Descriptor: | Cytochrome P450 cypX, GLYCEROL, MAGNESIUM ION, ... | Authors: | Cryle, M.J, Schlichting, I. | Deposit date: | 2010-06-04 | Release date: | 2010-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry, 49, 2010
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3N9U
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![BU of 3n9u by Molmil](/molmil-images/mine/3n9u) | Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 7, GLYCEROL | Authors: | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Moche, M, Nielsen, T.N, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2010-05-31 | Release date: | 2010-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im To be Published
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3NEX
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![BU of 3nex by Molmil](/molmil-images/mine/3nex) | |
3NI8
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![BU of 3ni8 by Molmil](/molmil-images/mine/3ni8) | Crystal Structure of PFC0360w, an HSP90 activator from plasmodium falciparum | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, PFC0360w protein | Authors: | Wernimont, A.K, Hutchinson, A, Sullivan, H, MacKenzie, F, Kozieradzki, I, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Pizzaro, J.C, Hills, T, Structural Genomics Consortium (SGC) | Deposit date: | 2010-06-15 | Release date: | 2010-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of PFC0360w, an HSP90 activator from plasmodium falciparum To be Published
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3NZT
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![BU of 3nzt by Molmil](/molmil-images/mine/3nzt) | 2.0 Angstrom Crystal structure of Glutamate--Cysteine Ligase (gshA) ftom Francisella tularensis in Complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Glutamate--cysteine ligase, SULFATE ION | Authors: | Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-07-16 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 2.0 Angstrom Crystal structure of Glutamate--Cysteine Ligase (gshA) ftom Francisella tularensis in Complex with AMP. To be Published
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3O2R
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![BU of 3o2r by Molmil](/molmil-images/mine/3o2r) | Structural flexibility in region involved in dimer formation of nuclease domain of Ribonuclase III (rnc) from Campylobacter jejuni | Descriptor: | CHLORIDE ION, Ribonuclease III | Authors: | Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-07-22 | Release date: | 2010-08-04 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.251 Å) | Cite: | Structural Flexibility in Region Involved in Dimer Formation of Nuclease Domain of Ribonuclase III (rnc) from Campylobacter jejuni. TO BE PUBLISHED
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3O4M
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![BU of 3o4m by Molmil](/molmil-images/mine/3o4m) | Crystal structure of porcine pancreatic phospholipase A2 in complex with 1,2-dihydroxybenzene | Descriptor: | CALCIUM ION, CATECHOL, Phospholipase A2, ... | Authors: | Dileep, K.V, Tintu, I, Karthe, P, Mandal, P.K, Haridas, M, Sadasivan, C. | Deposit date: | 2010-07-27 | Release date: | 2010-08-25 | Last modified: | 2011-11-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Binding to PLA(2) may contribute to the anti-inflammatory activity of catechol Chem.Biol.Drug Des., 2011
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3NVA
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![BU of 3nva by Molmil](/molmil-images/mine/3nva) | Dimeric form of CTP synthase from Sulfolobus solfataricus | Descriptor: | CTP synthase | Authors: | Harris, P, Willemoes, M, Lauritsen, I, Johansson, E, Jensen, K.F. | Deposit date: | 2010-07-08 | Release date: | 2010-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.504 Å) | Cite: | Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus Acta Crystallogr.,Sect.F, 67, 2011
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3NX7
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![BU of 3nx7 by Molmil](/molmil-images/mine/3nx7) | Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-Hydroxy-2-(N-(2-hydroxyethyl)4-methoxyphenylsulfonamido)acetamide | Descriptor: | CALCIUM ION, Macrophage metalloelastase, N-hydroxy-N~2~-(2-hydroxyethyl)-N~2~-[(4-methoxyphenyl)sulfonyl]glycinamide, ... | Authors: | Bertini, I, Calderone, V, Fragai, M, Giachetti, A, Loconte, M, Luchinat, C, Maletta, M, Nativi, C, Yeo, K.J. | Deposit date: | 2010-07-13 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases J.Am.Chem.Soc., 129, 2007
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