2F95
| M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure | Descriptor: | RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ... | Authors: | Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I. | Deposit date: | 2005-12-05 | Release date: | 2006-03-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Development of the signal in sensory rhodopsin and its transfer to the cognate transducer. Nature, 440, 2006
|
|
6HCE
| |
6EP4
| Human butyrylcholinesterase in complex with decamethonium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Nachon, F, Brazzolotto, X, Wandhammer, M, Trovaslet-Leroy, M, Rosenberry, T.L, Macdonald, I.R, Darvesh, S. | Deposit date: | 2017-10-10 | Release date: | 2017-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.30005383 Å) | Cite: | Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study. Molecules, 22, 2017
|
|
2F9M
| 3D structure of active human Rab11b GTPase | Descriptor: | MAGNESIUM ION, NICKEL (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Scapin, S.M.N, Guimaraes, B.G, Zanchin, N.I.T. | Deposit date: | 2005-12-06 | Release date: | 2006-04-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform. J.Struct.Biol., 154, 2006
|
|
1RJF
| Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, carboxy methyl transferase for protein phosphatase 2A catalytic subunit | Authors: | Leulliot, N, Quevillon-Cheruel, S, Sorel, I, de La Sierra-Gallay, I.L, Collinet, B, Graille, M, Blondeau, K, Bettache, N, Poupon, A, Janin, J, van Tilbeurgh, H. | Deposit date: | 2003-11-19 | Release date: | 2003-12-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity J.Biol.Chem., 279, 2004
|
|
7W1E
| Crystal structure of Klebsiella pneumoniae K1 capsule-specific polysaccharide lyase in complex with products | Descriptor: | 2,6-anhydro-4,5-O-[(1R)-1-carboxyethylidene]-3-deoxy-L-threo-hex-2-enonic acid, 3-O-acetyl-6-deoxy-alpha-L-galactopyranose-(1-3)-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Tu, I.F, Huang, K.F, Wu, S.H. | Deposit date: | 2021-11-19 | Release date: | 2022-05-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use. J.Biomed.Sci., 29, 2022
|
|
2ATE
| Structure of the complex of PurE with NitroAIR | Descriptor: | ((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE, Phosphoribosylaminoimidazole carboxylase catalytic subunit | Authors: | Kappock, T.J, Mathews, I.I, Zaugg, J.B, Peng, P, Hoskins, A.A, Okamoto, A, Ealick, S.E, Stubbe, J. | Deposit date: | 2005-08-24 | Release date: | 2006-08-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis. Biochemistry, 46, 2007
|
|
6HKP
| Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP2 (970-992) | Descriptor: | Apoptosis-stimulating of p53 protein 2, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Leissing, T.M, Clifton, I.J, Lu, X, Schofield, C.J. | Deposit date: | 2018-09-07 | Release date: | 2019-09-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP2 (970-992) To Be Published
|
|
6EQQ
| Human butyrylcholinesterase in complex with huprine 19 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... | Authors: | Nachon, F, Brazzolotto, X, Wandhammer, M, Trovaslet-Leroy, M, Rosenberry, T.L, Macdonald, I.R, Darvesh, S. | Deposit date: | 2017-10-15 | Release date: | 2017-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.40000439 Å) | Cite: | Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study. Molecules, 22, 2017
|
|
2Q0Q
| Structure of the Native M. Smegmatis Aryl Esterase | Descriptor: | GLYCEROL, SULFATE ION, aryl esterase | Authors: | Mathews, I.I, Soltis, M, Saldajeno, M, Ganshaw, G, Sala, R, Weyler, W, Cervin, M.A, Whited, G, Bott, R. | Deposit date: | 2007-05-22 | Release date: | 2007-12-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a novel enzyme that catalyzes acyl transfer to alcohols in aqueous conditions. Biochemistry, 46, 2007
|
|
2HTE
| The crystal structure of spermidine synthase from p. falciparum in complex with 5'-methylthioadenosine | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, SULFATE ION, ... | Authors: | Qiu, W, Dong, A, Ren, H, Wu, H, Wasney, G, Vedadi, M, Lew, J, Kozieradski, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Plotnikov, A.N, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2006-07-25 | Release date: | 2006-08-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
|
|
7KQO
| |
1JKX
| Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase | Descriptor: | N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | Authors: | Greasley, S.E, Marsilje, T.H, Cai, H, Baker, S, Benkovic, S.J, Boger, D.L, Wilson, I.A. | Deposit date: | 2001-07-13 | Release date: | 2001-11-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase. Biochemistry, 40, 2001
|
|
6MUB
| Anti-HIV-1 Fab 2G12 + Man5 re-refinement | Descriptor: | Fab 2G12, heavy chain, light chain, ... | Authors: | Wilson, I.A, Calarese, D.A, Stanfield, R.L. | Deposit date: | 2018-10-22 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
5LAL
| Structure of Arabidopsis dirigent protein AtDIR6 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dirigent protein 6, ... | Authors: | Gasper, R, Kolesinski, P, Terlecka, B, Effenberger, I, Schaller, A, Hofmann, E. | Deposit date: | 2016-06-14 | Release date: | 2016-11-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Dirigent Protein Mode of Action Revealed by the Crystal Structure of AtDIR6. Plant Physiol., 172, 2016
|
|
6T4D
| Crystal structure of Plasmodium falciparum Morn1 | Descriptor: | Morn1, ZINC ION | Authors: | Grishkovskaya, I, Kostan, J, Sajko, S, Morriswood, B, Djinovic-Carugo, K. | Deposit date: | 2019-10-13 | Release date: | 2020-11-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats. Plos One, 15, 2020
|
|
1SWU
| STREPTAVIDIN MUTANT Y43F | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, STREPTAVIDIN | Authors: | Freitag, S, Le Trong, I, Klumb, L.A, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 1998-10-12 | Release date: | 1999-11-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Atomic resolution structure of biotin-free Tyr43Phe streptavidin: what is in the binding site? Acta Crystallogr.,Sect.D, 55, 1999
|
|
6T69
| Crystal structure of Toxoplasma gondii Morn1(V shape) | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Membrane occupation and recognition nexus protein MORN1, ... | Authors: | Grishkovskaya, I, Kostan, J, Sajko, S, Morriswood, B, Djinovic-Carugo, K. | Deposit date: | 2019-10-18 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats. Plos One, 15, 2020
|
|
5KNB
| Crystal structure of the 2 ADP-bound V1 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Suzuki, K, Mizutani, K, Maruyama, S, Shimono, K, Imai, F.L, Muneyuki, E, Kakinuma, Y, Ishizuka-Katsura, Y, Shirouzu, M, Yokoyama, S, Yamato, I, Murata, T. | Deposit date: | 2016-06-28 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.251 Å) | Cite: | Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor Nat Commun, 7, 2016
|
|
6N2V
| |
6T40
| Bovine enterovirus F3 in complex with a Cysteinylglycine dipeptide | Descriptor: | CHLORIDE ION, CYSTEINE, GLYCEROL, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Walter, T.S, Fry, E.E, Stuart, D.I. | Deposit date: | 2019-10-11 | Release date: | 2020-08-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Glutathione facilitates enterovirus assembly by binding at a druggable pocket. Commun Biol, 3, 2020
|
|
6T7O
| X-ray structure of the C-terminal domain of S. aureus Hibernating Promoting Factor (CTD-SaHPF) | Descriptor: | Ribosome hibernation promotion factor | Authors: | Fatkhullin, B.F, Khusainov, I.S, Ayupov, R.K, Gabdulkhakov, A.G, Tishchenko, S.V, Validov, S.Z, Yusupov, M.M. | Deposit date: | 2019-10-22 | Release date: | 2019-12-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.60003626 Å) | Cite: | Dimerization of long hibernation promoting factor from Staphylococcus aureus: Structural analysis and biochemical characterization. J.Struct.Biol., 209, 2020
|
|
2AOG
| Crystal structure analysis of HIV-1 protease mutant V82A with a substrate analog P2-NC | Descriptor: | ACETIC ACID, GLYCEROL, HIV-1 PROTEASE (RETROPEPSIN), ... | Authors: | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | Deposit date: | 2005-08-12 | Release date: | 2006-01-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005
|
|
6T8H
| Cryo-EM structure of the DNA-bound PolD-PCNA processive complex from P. abyssi | Descriptor: | DNA polymerase II small subunit, DNA polymerase sliding clamp, DNA primer, ... | Authors: | Madru, C, Raia, P, Hugonneau Beaufet, I, Pehau-Arnaudet, G, England, P, Lindhal, E, Delarue, M, Carroni, M, Sauguet, L. | Deposit date: | 2019-10-24 | Release date: | 2020-03-04 | Last modified: | 2020-04-08 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
|
|
2AQB
| Structure-activity relationships at the 5-position of thiolactomycin: an intact 5(R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherchia coli | Descriptor: | (5R)-5-[(1E)-BUTA-1,3-DIENYL]-4-HYDROXY-3,5-DIMETHYLTHIOPHEN-2(5H)-ONE, 3-oxoacyl-[acyl-carrier-protein] synthase I | Authors: | Kim, P, Zhang, Y.M, Shenoy, G, Nguyen, Q.A, Boshoff, H.I, Manjunatha, U.H, Goodwin, M.B, Lonsdale, J, Price, A.C, Miller, D.J. | Deposit date: | 2005-08-17 | Release date: | 2006-01-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure-Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli J.Med.Chem., 49, 2006
|
|