6HKP
Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP2 (970-992)
Summary for 6HKP
Entry DOI | 10.2210/pdb6hkp/pdb |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, Apoptosis-stimulating of p53 protein 2, SULFATE ION, ... (7 entities in total) |
Functional Keywords | non-heme, dioxygenase, oxygenase, metal-binding, transcription, double stranded beta-helix, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, epigenetic regulation, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase, ankyrin repeat domain, apoptosis, p53 binding protein, ank repeat, sh3 domain, ankyrin repeats, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 44084.34 |
Authors | Leissing, T.M.,Clifton, I.J.,Lu, X.,Schofield, C.J. (deposition date: 2018-09-07, release date: 2019-09-18, Last modification date: 2024-01-17) |
Primary citation | Leissing, T.M.,Clifton, I.J.,Lu, X.,Schofield, C.J. Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP2 (970-992) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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