6HKP
Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP2 (970-992)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 350 | 40415.4 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (Human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
| 2 | B (S) | Apoptosis-stimulating of p53 protein 2 | polymer | 23 | 2419.6 | 1 | UniProt (Q13625) Pfam (PF00023) | Homo sapiens | Bcl2-binding protein,Bbp,Renal carcinoma antigen NY-REN-51,Tumor suppressor p53-binding protein 2,p53BP2 |
| 3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | I, J, K, L, M (A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | N (A) | N-OXALYLGLYCINE | non-polymer | 147.1 | 1 | Chemie (OGA) | |||
| 6 | O (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | P, Q (A, S) | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: Q9NWT6)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42835.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1249.3 | |
| All* | Total formula weight | 44084.3 |
