3RU3
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![BU of 3ru3 by Molmil](/molmil-images/mine/3ru3) | Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NADPH and ATP. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, BETA-6-HYDROXY-1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... | Authors: | Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W. | Deposit date: | 2011-05-04 | Release date: | 2011-06-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.605 Å) | Cite: | Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
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2X45
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![BU of 2x45 by Molmil](/molmil-images/mine/2x45) | Crystal Structure of Arg r 1 in complex with histamine | Descriptor: | ALLERGEN ARG R 1, HISTAMINE | Authors: | Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I. | Deposit date: | 2010-01-28 | Release date: | 2011-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick To be Published
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4HVY
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![BU of 4hvy by Molmil](/molmil-images/mine/4hvy) | A thermostable variant of human NUDT18 NUDIX domain obtained by Hot Colony Filtration | Descriptor: | GLYCEROL, MAGNESIUM ION, Nucleoside diphosphate-linked moiety X motif 18, ... | Authors: | Asial, I, Cheng, Y.X, Engman, H, Wu, B, Dollhopf, M, Nordlund, P, Cornvik, T. | Deposit date: | 2012-11-07 | Release date: | 2014-01-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell. Nat Commun, 4, 2013
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4HYW
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![BU of 4hyw by Molmil](/molmil-images/mine/4hyw) | Pyruvate kinase (PYK) from Trypanosoma brucei in the presence of Magnesium and F26BP | Descriptor: | 2,6-di-O-phosphono-beta-D-fructofuranose, CHLORIDE ION, GLYCEROL, ... | Authors: | Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | Deposit date: | 2012-11-14 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | `In crystallo' substrate binding triggers major domain movements and reveals magnesium as a co-activator of Trypanosoma brucei pyruvate kinase. Acta Crystallogr.,Sect.D, 69, 2013
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4DP7
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![BU of 4dp7 by Molmil](/molmil-images/mine/4dp7) | The 1.08 Angstrom crystal structure of oxidized (CuII) poplar plastocyanin A at pH 4.0 | Descriptor: | COPPER (II) ION, Plastocyanin A, chloroplastic, ... | Authors: | Kachalova, G.S, Shosheva, A.H, Bourenkov, G.P, Donchev, A.A, Dimitrov, M.I, Bartunik, H.D. | Deposit date: | 2012-02-13 | Release date: | 2013-02-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Structural comparison of the poplar plastocyanin isoforms PCa and PCb sheds new light on the role of the copper site geometry in interactions with redox partners in oxygenic photosynthesis. J.Inorg.Biochem., 115, 2012
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1GBV
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![BU of 1gbv by Molmil](/molmil-images/mine/1gbv) | (ALPHA-OXY, BETA-(C112G)DEOXY) T-STATE HUMAN HEMOGLOBIN | Descriptor: | HEMOGLOBIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Vasquez, G.B, Ji, X, Pechik, I, Fronticelli, C, Gilliland, G.L. | Deposit date: | 1995-12-20 | Release date: | 1997-01-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cysteines beta93 and beta112 as probes of conformational and functional events at the human hemoglobin subunit interfaces. Biophys.J., 76, 1999
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1G3U
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![BU of 1g3u by Molmil](/molmil-images/mine/1g3u) | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE MONOPHOSPHATE (TMP) | Descriptor: | MAGNESIUM ION, SULFATE ION, THYMIDINE-5'-PHOSPHATE, ... | Authors: | Li de la Sierra, I, Munier-Lehmann, H, Gilles, A.M, Barzu, O, Delarue, M. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution. J.Mol.Biol., 311, 2001
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1G4H
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![BU of 1g4h by Molmil](/molmil-images/mine/1g4h) | LINB COMPLEXED WITH BUTAN-1-OL | Descriptor: | 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE, 1-BUTANOL, CALCIUM ION, ... | Authors: | Oakley, A.J, Prokop, Z, Bohac, M, Kmunicek, J, Jedlicka, T, Monincova, M, Kuta-Smatanova, I, Nagata, Y, Damborsky, J, Wilce, M.C.J. | Deposit date: | 2000-10-27 | Release date: | 2001-10-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition. Biochemistry, 41, 2002
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1BWW
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![BU of 1bww by Molmil](/molmil-images/mine/1bww) | BENCE-JONES IMMUNOGLOBULIN REI VARIABLE PORTION, T39K MUTANT | Descriptor: | PROTEIN (IG KAPPA CHAIN V-I REGION REI) | Authors: | Uson, I, Pohl, E, Schneider, T.R, Dauter, Z, Schmidt, A, Fritz, H.J, Sheldrick, G.M. | Deposit date: | 1998-09-29 | Release date: | 1998-10-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | 1.7 A structure of the stabilized REIv mutant T39K. Application of local NCS restraints. Acta Crystallogr.,Sect.D, 55, 1999
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1C3E
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![BU of 1c3e by Molmil](/molmil-images/mine/1c3e) | NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID. | Descriptor: | 2-{4-[2-(2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL)-1-CARBOXY-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, GLYCINAMIDE RIBONUCLEOTIDE, GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | Authors: | Greasley, S.E, Yamashita, M.M, Cai, H, Benkovic, S.J, Boger, D.L, Wilson, I.A. | Deposit date: | 1999-07-27 | Release date: | 1999-12-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid. Biochemistry, 38, 1999
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3BP9
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![BU of 3bp9 by Molmil](/molmil-images/mine/3bp9) | Structure of B-tropic MLV capsid N-terminal domain | Descriptor: | GLYCEROL, Gag protein, ISOPROPYL ALCOHOL | Authors: | Gulnahar, M.B, Dodding, M.P, Goldstone, D.C, Haire, L.F, Stoye, J.P, Taylor, I.A. | Deposit date: | 2007-12-18 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation J.Mol.Biol., 376, 2008
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3WBZ
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![BU of 3wbz by Molmil](/molmil-images/mine/3wbz) | Crystal structure of C. albicans tRNA(His) guanylyltransferase (Thg1) with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Likely histidyl tRNA-specific guanylyltransferase, MAGNESIUM ION | Authors: | Nakamura, A, Nemoto, T, Sonoda, T, Yamashita, K, Tanaka, I, Yao, M. | Deposit date: | 2013-05-24 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.392 Å) | Cite: | Structural basis of reverse nucleotide polymerization Proc.Natl.Acad.Sci.USA, 110, 2013
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3BZL
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![BU of 3bzl by Molmil](/molmil-images/mine/3bzl) | Crystal structural of native EscU C-terminal domain | Descriptor: | EscU, FORMIC ACID, SODIUM ION | Authors: | Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J. | Deposit date: | 2008-01-18 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS. Nature, 453, 2008
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1FVU
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![BU of 1fvu by Molmil](/molmil-images/mine/1fvu) | CRYSTAL STRUCTURE OF BOTROCETIN | Descriptor: | BOTROCETIN ALPHA CHAIN, BOTROCETIN BETA CHAIN, MAGNESIUM ION | Authors: | Sen, U, Vasudevan, S, Subbarao, G, McClintoc, R.A, Celikel, R, Ruggeri, Z.M, Varughese, K.I. | Deposit date: | 2000-09-20 | Release date: | 2001-02-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the von Willebrand factor modulator botrocetin. Biochemistry, 40, 2001
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1G5F
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![BU of 1g5f by Molmil](/molmil-images/mine/1g5f) | STRUCTURE OF LINB COMPLEXED WITH 1,2-DICHLOROETHANE | Descriptor: | 1,2-DICHLOROETHANE, 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE, CALCIUM ION, ... | Authors: | Oakley, A.J, Prokop, Z, Bohac, M, Kmunicek, J, Jedlicka, T, Monincova, M, Kuta-Smatanova, I, Nagata, Y, Damborsky, J, Wilce, M.C.J. | Deposit date: | 2000-11-01 | Release date: | 2001-11-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition. Biochemistry, 41, 2002
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1GGC
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1G5N
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![BU of 1g5n by Molmil](/molmil-images/mine/1g5n) | ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES | Descriptor: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ANNEXIN V, CALCIUM ION | Authors: | Capila, I, Heraiz, M.J, Mo, Y.D, Mealy, T.R, Campos, B, Dedman, J.R, Linhardt, R.J, Seaton, B.A. | Deposit date: | 2000-11-01 | Release date: | 2001-06-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Annexin V--heparin oligosaccharide complex suggests heparan sulfate--mediated assembly on cell surfaces. Structure, 9, 2001
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1GGI
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![BU of 1ggi by Molmil](/molmil-images/mine/1ggi) | CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN | Descriptor: | HIV-1 V3 LOOP PEPTIDE ANTIGEN, IGG2A 50.1 FAB (HEAVY CHAIN), IGG2A 50.1 FAB (LIGHT CHAIN) | Authors: | Stanfield, R.L, Rini, J.M, Wilson, I.A. | Deposit date: | 1993-04-02 | Release date: | 1993-10-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen. Proc.Natl.Acad.Sci.USA, 90, 1993
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1GDE
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![BU of 1gde by Molmil](/molmil-images/mine/1gde) | CRYSTAL STRUCTURE OF PYROCOCCUS PROTEIN A-1 E-FORM | Descriptor: | ASPARTATE AMINOTRANSFERASE, GLUTAMIC ACID, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ura, H, Harata, K, Matsui, I, Kuramitsu, S. | Deposit date: | 2000-09-23 | Release date: | 2001-09-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Temperature dependence of the enzyme-substrate recognition mechanism. J.Biochem., 129, 2001
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1MJ8
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![BU of 1mj8 by Molmil](/molmil-images/mine/1mj8) | High Resolution Crystal Structure Of The Fab Fragment of The Esterolytic Antibody MS6-126 | Descriptor: | GLYCEROL, IMMUNOGLOBULIN MS6-126, PHOSPHATE ION | Authors: | Ruzheinikov, S.N, Muranova, T.A, Sedelnikova, S.E, Partridge, L.J, Blackburn, G.M, Murray, I.A, Kakinuma, H, Takashi, N, Shimazaki, K, Sun, J, Nishi, Y, Rice, D.W. | Deposit date: | 2002-08-27 | Release date: | 2003-09-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity J.Mol.Biol., 332, 2003
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3ZE6
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![BU of 3ze6 by Molmil](/molmil-images/mine/3ze6) | 3D structure of the Ni-Fe-Se hydrogenase from D. vulgaris Hildenborough in the as-isolated oxidized state at 1.50 Angstroms | Descriptor: | 3-[DODECYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, BIS-(MU-2-OXO),[(MU-3--SULFIDO)-BIS(MU-2--SULFIDO)-TRIS(CYS-S)-TRI-IRON] (AQUA)(GLU-O)IRON(II), CARBONMONOXIDE-(DICYANO) IRON, ... | Authors: | Marques, M.C, Coelho, R, Pereira, I.A.C, Matias, P.M. | Deposit date: | 2012-12-03 | Release date: | 2013-06-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Redox State-Dependent Changes in the Crystal Structure of [Nifese] Hydrogenase from Desulfovibrio Vulgaris Hildenborough Int.J.Hydrogen Energy, 2013
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8QAE
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![BU of 8qae by Molmil](/molmil-images/mine/8qae) | X-ray crystal structure of a de novo designed single-chain antiparallel 6-helix alpha-helical barrel, sc-apCC-6-SLLA | Descriptor: | 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol, PENTAETHYLENE GLYCOL, sc-apCC-6-SLLA | Authors: | Albanese, K.I, Petrenas, R, Woolfson, D.N. | Deposit date: | 2023-08-22 | Release date: | 2024-07-03 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Rationally seeded computational protein design of ɑ-helical barrels. Nat.Chem.Biol., 20, 2024
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8QAG
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![BU of 8qag by Molmil](/molmil-images/mine/8qag) | X-ray crystal structure of a de novo designed single-chain parallel coiled-coil alpha-helical barrel with 6 inner helices, sc-CC-6-95 | Descriptor: | DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, sc-CC-6-95 | Authors: | Petrenas, R, Albanese, K.I, Woolfson, D.N. | Deposit date: | 2023-08-22 | Release date: | 2024-07-03 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Rationally seeded computational protein design of ɑ-helical barrels. Nat.Chem.Biol., 20, 2024
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7TA5
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![BU of 7ta5 by Molmil](/molmil-images/mine/7ta5) | |
8QAH
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![BU of 8qah by Molmil](/molmil-images/mine/8qah) | |