5MSY
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![BU of 5msy by Molmil](/molmil-images/mine/5msy) | Glycoside hydrolase BT_1012 | Descriptor: | AMMONIA, Glycoside hydrolase, PHOSPHATE ION | Authors: | Basle, A, Ndeh, D, Rogowski, A, Cartmell, A, Luis, A.S, Venditto, I, Labourel, A, Gilbert, H.J. | Deposit date: | 2017-01-06 | Release date: | 2017-03-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature, 544, 2017
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2O70
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![BU of 2o70 by Molmil](/molmil-images/mine/2o70) | Structure of OHCU decarboxylase from zebrafish | Descriptor: | OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-09 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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1TZP
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![BU of 1tzp by Molmil](/molmil-images/mine/1tzp) | MEPA, inactive form without ZN in P21 | Descriptor: | 1,4-BUTANEDIOL, Penicillin-insensitive murein endopeptidase, SULFATE ION | Authors: | Marcyjaniak, M, Odintsov, S.G, Sabala, I, Bochtler, M. | Deposit date: | 2004-07-11 | Release date: | 2004-09-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Peptidoglycan amidase MepA is a LAS metallopeptidase J.Biol.Chem., 279, 2004
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7AC4
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![BU of 7ac4 by Molmil](/molmil-images/mine/7ac4) | Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source | Descriptor: | Insulin, R-1,2-PROPANEDIOL, SODIUM ION | Authors: | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | Deposit date: | 2020-09-09 | Release date: | 2021-09-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Versatile microporous polymer-based supports for serial macromolecular crystallography. Acta Crystallogr D Struct Biol, 77, 2021
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7AC3
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![BU of 7ac3 by Molmil](/molmil-images/mine/7ac3) | Structure of thaumatin collected by rotation serial crystallography on a COC membrane at a synchrotron source | Descriptor: | L(+)-TARTARIC ACID, S-1,2-PROPANEDIOL, SODIUM ION, ... | Authors: | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | Deposit date: | 2020-09-09 | Release date: | 2021-09-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Versatile microporous polymer-based supports for serial macromolecular crystallography. Acta Crystallogr D Struct Biol, 77, 2021
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1K5W
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![BU of 1k5w by Molmil](/molmil-images/mine/1k5w) | THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE | Descriptor: | CALCIUM ION, Synaptotagmin I | Authors: | Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J. | Deposit date: | 2001-10-12 | Release date: | 2002-01-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron, 32, 2001
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7RYP
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![BU of 7ryp by Molmil](/molmil-images/mine/7ryp) | Cryo-EM structure of KIFBP:KIF15 | Descriptor: | KIF-binding protein, Kinesin-like protein KIF15 | Authors: | Solon, A.L, Tan, Z, Schutt, K.L, Jepsen, L, Haynes, S.E, Nesvizhskii, A.I, Sept, D, Stumpff, J, Ohi, R, Cianfrocco, M.A. | Deposit date: | 2021-08-25 | Release date: | 2021-09-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding. Sci Adv, 7, 2021
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4GTE
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![BU of 4gte by Molmil](/molmil-images/mine/4gte) | T. Maritima FDTS (E144R mutant) with FAD and Folate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, N-({4-[(6aR)-3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]phenyl}carbonyl)-L-glutamic acid, Thymidylate synthase thyX | Authors: | Mathews, I.I, Lesley, S.A, Kohen, A, Prabhakar, A. | Deposit date: | 2012-08-28 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Folate binding site of flavin-dependent thymidylate synthase. Proc.Natl.Acad.Sci.USA, 109, 2012
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5MEF
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![BU of 5mef by Molmil](/molmil-images/mine/5mef) | Cyanothece lipoxygenase 2 (CspLOX2) variant - L304F | Descriptor: | Arachidonate 15-lipoxygenase, CHLORIDE ION, FE (III) ION, ... | Authors: | Newie, J, Neumann, P, Werner, M, Mata, R.A, Ficner, R, Feussner, I. | Deposit date: | 2016-11-14 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.357 Å) | Cite: | Lipoxygenase 2 from Cyanothece sp. controls dioxygen insertion by steric shielding and substrate fixation. Sci Rep, 7, 2017
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7ABD
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![BU of 7abd by Molmil](/molmil-images/mine/7abd) | Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-768 | Descriptor: | 1,2-ETHANEDIOL, 3-(3-cyclopentyloxy-4-methoxy-phenyl)-4,4-dimethyl-1~{H}-pyrazol-5-one, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Singh, A.K, Blaazer, A.R, Zara, L, de Esch, I.J.P, Leurs, R, Brown, D.G. | Deposit date: | 2020-09-07 | Release date: | 2021-10-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | hPDE4D2 structure with inhibitor NPD-768 To be published
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5MEX
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![BU of 5mex by Molmil](/molmil-images/mine/5mex) | Sulphotransferase-18 from Arabidopsis thaliana in complex with 3'-phosphoadenosine 5'-phosphate (PAP)and sinigrin | Descriptor: | 1,2-ETHANEDIOL, 1,3-BUTANEDIOL, 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Hirschmann, F, Krause, F, Baruch, P, Chizhov, I, Mueller, J.W, Manstein, D.J, Papenbrock, J, Fedorov, R. | Deposit date: | 2016-11-16 | Release date: | 2017-07-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism. Sci Rep, 7, 2017
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6DXH
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![BU of 6dxh by Molmil](/molmil-images/mine/6dxh) | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate | Descriptor: | 4-(4-tert-butylphenyl)-4-oxobutanoic acid, UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ... | Authors: | Harding, R.J, Mann, M.K, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Schapira, M, Structural Genomics Consortium (SGC) | Deposit date: | 2018-06-28 | Release date: | 2018-07-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain. J.Med.Chem., 62, 2019
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5MRA
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![BU of 5mra by Molmil](/molmil-images/mine/5mra) | human SCBD (sorcin calcium binding domain) in complex with doxorubicin | Descriptor: | DIMETHYL SULFOXIDE, DOXORUBICIN, MAGNESIUM ION, ... | Authors: | Ilari, A, Fiorillo, A, Colotti, G, Genovese, I. | Deposit date: | 2016-12-22 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.74 Å) | Cite: | Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells. Cell Death Dis, 8, 2017
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6DNP
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![BU of 6dnp by Molmil](/molmil-images/mine/6dnp) | Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-F-3-Methyl-6-F-phenyldiketoacid | Descriptor: | (2Z)-4-(2,6-difluoro-3-methylphenyl)-2-hydroxy-4-oxobut-2-enoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | Authors: | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC), Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | Deposit date: | 2018-06-07 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.711 Å) | Cite: | Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58, 2018
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6RU9
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![BU of 6ru9 by Molmil](/molmil-images/mine/6ru9) | |
1JXF
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![BU of 1jxf by Molmil](/molmil-images/mine/1jxf) | SOLUTION STRUCTURE OF REDUCED CU(I) PLASTOCYANIN FROM SYNECHOCYSTIS PCC6803 | Descriptor: | COPPER (II) ION, PLASTOCYANIN | Authors: | Bertini, I, Bryant, D.A, Ciurli, S, Dikiy, A, Fernandez, C.O, Luchinat, C, Safarov, N, Vila, A.J, Zhao, J. | Deposit date: | 2001-09-07 | Release date: | 2001-09-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Backbone dynamics of plastocyanin in both oxidation states. Solution structure of the reduced form and comparison with the oxidized state. J.Biol.Chem., 276, 2001
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6Z06
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![BU of 6z06 by Molmil](/molmil-images/mine/6z06) | Crystal structure of Puumala virus Gc in complex with Fab 4G2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab 4G2 Heavy chain, ... | Authors: | Rissanen, I.R, Stass, R, Krumm, S.A, Seow, J, Hulswit, R.J.G, Paesen, G.C, Hepojoki, J, Vapalahti, O, Lundkvist, A, Reynard, O, Volchkov, V, Doores, K.J, Huiskonen, J.T, Bowden, T.A. | Deposit date: | 2020-05-07 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein. Elife, 9, 2020
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1NVG
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![BU of 1nvg by Molmil](/molmil-images/mine/1nvg) | N249Y MUTANT OF THE ALCOHOL DEHYDROGENASE FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS-TETRAGONAL CRYSTAL FORM | Descriptor: | NAD-dependent alcohol dehydrogenase, ZINC ION | Authors: | Esposito, L, Bruno, I, Sica, F, Raia, C.A, Giordano, A, Rossi, M, Mazzarella, L, Zagari, A. | Deposit date: | 2003-02-03 | Release date: | 2003-08-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural study of a single-point mutant of Sulfolobus solfataricus alcohol dehydrogenase with enhanced activity Febs Lett., 539, 2003
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7BOH
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![BU of 7boh by Molmil](/molmil-images/mine/7boh) | Complete Bacterial 30S ribosomal subunit assembly complex state E (+RbfA)(Consensus Refinement) | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | Deposit date: | 2021-01-25 | Release date: | 2021-12-08 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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2O3W
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![BU of 2o3w by Molmil](/molmil-images/mine/2o3w) | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site in presence of paromomycin | Descriptor: | PAROMOMYCIN, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | Authors: | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | Deposit date: | 2006-12-02 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites. Chembiochem, 8, 2007
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2O73
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![BU of 2o73 by Molmil](/molmil-images/mine/2o73) | Structure of OHCU decarboxylase in complex with allantoin | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-10 | Release date: | 2007-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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6YUX
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![BU of 6yux by Molmil](/molmil-images/mine/6yux) | Crystal structure of Malus domestica Double Bond Reductase (MdDBR) ternary complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, ... | Authors: | Caliandro, R, Polsinelli, I, Demitri, N, Benini, S. | Deposit date: | 2020-04-27 | Release date: | 2021-02-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | The structural and functional characterization of Malus domestica double bond reductase MdDBR provides insights towards the identification of its substrates. Int.J.Biol.Macromol., 171, 2021
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5OMB
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![BU of 5omb by Molmil](/molmil-images/mine/5omb) | Crystal structure of K. lactis Ddc2 N-terminus in complex with S. cerevisiae Rfa1 N-OB domain | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA damage checkpoint protein LCD1, ... | Authors: | Deshpande, I, Seeber, A, Shimada, K, Keusch, J.J, Gut, H, Gasser, S.M. | Deposit date: | 2017-07-28 | Release date: | 2017-10-25 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. Mol. Cell, 68, 2017
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3ZTS
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![BU of 3zts by Molmil](/molmil-images/mine/3zts) | Hexagonal form P6122 of the Aquifex aeolicus nucleoside diphosphate kinase (FINAL STAGE OF RADIATION DAMAGE) | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE | Authors: | Boissier, F, Georgescauld, F, Moynie, L, Dupuy, J.-W, Sarger, C, Podar, M, Lascu, I, Giraud, M.-F, Dautant, A. | Deposit date: | 2011-07-12 | Release date: | 2012-03-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Inter-Subunit Disulphide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus Proteins, 80, 2012
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3ZTR
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![BU of 3ztr by Molmil](/molmil-images/mine/3ztr) | Hexagonal form P6122 of the Aquifex aeolicus nucleoside diphosphate kinase (FIRST STAGE OF RADIATION DAMAGE) | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE | Authors: | Boissier, F, Georgescauld, F, Moynie, L, Dupuy, J.-W, Sarger, C, Podar, M, Lascu, I, Giraud, M.-F, Dautant, A. | Deposit date: | 2011-07-12 | Release date: | 2012-03-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Inter-Subunit Disulphide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus Proteins, 80, 2012
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