4NCQ
 
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3AGK
 | | Crystal structure of archaeal translation termination factor, aRF1 | | 分子名称: | Peptide chain release factor subunit 1 | | 著者 | Kobayashi, K, Kikuno, I, Ishitani, R, Ito, K, Nureki, O. | | 登録日 | 2010-04-01 | | 公開日 | 2010-11-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Omnipotent role of archaeal elongation factor 1 alpha (EF1{alpha}) in translational elongation and termination, and quality control of protein synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
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2ZYL
 | | Crystal structure of 3-ketosteroid-9-alpha-hydroxylase (KshA) from M. tuberculosis | | 分子名称: | FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, POSSIBLE OXIDOREDUCTASE, ... | | 著者 | D'Angelo, I, Capyk, J, Strynadka, N, Eltis, L. | | 登録日 | 2009-01-27 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis
J.Biol.Chem., 284, 2009
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2ZYQ
 | | Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis | | 分子名称: | D(-)-TARTARIC ACID, FE (II) ION, PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC | | 著者 | D'Angelo, I, Yam, K.C, Eltis, L.D, Strynadka, N. | | 登録日 | 2009-01-28 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.
Plos Pathog., 5, 2009
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4NML
 | | 2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from Toxoplasma gondii ME49 in complex with DL-Malic acid | | 分子名称: | CHLORIDE ION, D-MALATE, Ribulose 5-phosphate isomerase | | 著者 | Halavaty, A.S, Dubrovska, I, Flores, K, Shanmugam, D, Shuvalova, L, Roos, D, Ruan, J, Ngo, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-11-15 | | 公開日 | 2013-12-04 | | 最終更新日 | 2021-01-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
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3A7G
 | | Human MST3 kinase | | 分子名称: | Serine/threonine kinase 24 (STE20 homolog, yeast) | | 著者 | Ko, T.P, Jeng, W.Y, Liu, C.I, Lai, M.D, Wang, A.H.J. | | 登録日 | 2009-09-26 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of human MST3 kinase in complex with adenine, ADP and Mn2+.
Acta Crystallogr.,Sect.D, 66, 2010
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3A7Y
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3AGE
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3A8A
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4NQM
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with a triazolo-phthalazine ligand | | 分子名称: | 2-chloro-N-[5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-(morpholin-4-yl)phenyl]benzenesulfonamide, Bromodomain-containing protein 4, SUCCINIC ACID | | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2013-11-25 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal Structure of the first bromodomain of human BRD4 in complex with a triazolo-phthalazine ligand
To be Published
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3AI0
 | | Crystal structure of beta-glucosidase from termite Neotermes koshunensis in complex with para-nitrophenyl-beta-D-glucopyranoside | | 分子名称: | 4-nitrophenyl beta-D-glucopyranoside, GLYCEROL, beta-glucosidase | | 著者 | Jeng, W.-Y, Liu, C.-I, Wang, A.H.-J. | | 登録日 | 2010-05-06 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural and functional analysis of three beta-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensis
J.Struct.Biol., 173, 2011
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2XS8
 | | Crystal Structure of ALIX in complex with the SIVagmTan-1 AYDPARKLL Late Domain | | 分子名称: | PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN, SIVAGMTAN-1 GAG P6 | | 著者 | Zhai, Q, Landesman, M, Robinson, H, Sundquist, W.I, Hill, C.P. | | 登録日 | 2010-09-24 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | Identification and Structural Characterization of the Alix-Binding Late Domains of Sivmac239 and Sivagmtan-1.
J.Virol., 85, 2011
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2Y60
 | | Isopenicillin N synthase with AC-D-methionine | | 分子名称: | FE (III) ION, GLYCEROL, ISOPENICILLIN N SYNTHASE, ... | | 著者 | Rutledge, P.J, Clifton, I.J, Ge, W. | | 登録日 | 2011-01-19 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The Crystal Structure of Isopenicillin N Synthase with Delta((L)-Alpha-Aminoadipoyl)-(L)-Cysteinyl-(D)-Methionine Reveals Thioether Coordination to Iron.
Arch.Biochem.Biophys., 516, 2011
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2XS6
 | | CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2 | | 分子名称: | CHLORIDE ION, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA | | 著者 | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P. | | 登録日 | 2010-09-24 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The Structure and Catalytic Mechanism of Human Sphingomyelin Phosphodiesterase Like 3A - an Acid Sphingomyelinase Homolog with a Novel Nucleotide Hydrolase Activity.
FEBS J., 283, 2016
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2Y4U
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4GCO
 | | Central domain of stress-induced protein-1 (STI-1) from C.elegans | | 分子名称: | Protein STI-1 | | 著者 | Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2012-07-30 | | 公開日 | 2012-08-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Central domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
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4NXY
 | | Crystal Structure of the GNAT domain of S. lividans PAT | | 分子名称: | Acyl-CoA synthetase, GLYCEROL, TRIFLUOROETHANOL | | 著者 | Rank, K.C, Tucker, A.C, Escalante-Semerena, J.C, Rayment, I. | | 登録日 | 2013-12-09 | | 公開日 | 2014-11-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | | 主引用文献 | Insights into the specificity of lysine acetyltransferases.
J.Biol.Chem., 289, 2014
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2XSQ
 | | Crystal structure of human Nudix motif 16 (NUDT16) in complex with IMP and magnesium | | 分子名称: | CHLORIDE ION, INOSINIC ACID, MAGNESIUM ION, ... | | 著者 | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van den Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P. | | 登録日 | 2010-09-29 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Structural Basis for the Specificity of Human Nudt16 and its Regulation by Inosine Monophosphate.
Plos One, 10, 2015
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4O1Y
 | | Crystal structure of Porcine Pancreatic Phospholipase A2 in complex with 1-Naphthaleneacetic acid | | 分子名称: | CALCIUM ION, NAPHTHALEN-1-YL-ACETIC ACID, Phospholipase A2, ... | | 著者 | Dileep, K.V, Remya, C, Tintu, I, Mandal, P.K, Karthe, P, Haridas, M, Sadasivan, C. | | 登録日 | 2013-12-16 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of Porcine Pancreatic Phospholipase A2 in complex with 1-Naphthaleneacetic acid
To be published
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4FXU
 | | Crystallographic structure of trimeric riboflavin synthase from Brucella abortus | | 分子名称: | Riboflavin synthase subunit alpha | | 著者 | Serer, M.I, Bonomi, H.R, Guimaraes, B.G, Rossi, R.C, Goldbaum, F.A, Klinke, S. | | 登録日 | 2012-07-03 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility.
Acta Crystallogr.,Sect.D, 70, 2014
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4FZ1
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2XCO
 | | The 3.1A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase | | 分子名称: | CALCIUM ION, DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A | | 著者 | Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N. | | 登録日 | 2010-04-24 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Nature, 466, 2010
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2XGY
 | | Complex of Rabbit Endogenous Lentivirus (RELIK)Capsid with Cyclophilin A | | 分子名称: | GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, RELIK CAPSID N-TERMINAL DOMAIN | | 著者 | Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A. | | 登録日 | 2010-06-08 | | 公開日 | 2010-09-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface.
Cell Host Microbe, 8, 2010
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2XUU
 | | Crystal structure of a DAP-kinase 1 mutant | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DEATH-ASSOCIATED PROTEIN KINASE 1, MAGNESIUM ION, ... | | 著者 | de Diego, I, Kuper, J, Lehmann, F, Wilmanns, M. | | 登録日 | 2010-10-21 | | 公開日 | 2011-11-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A Pef/Y Substrate Recognition and Signature Motif Plays a Critical Role in Dapk-Related Kinase Activity.
Chem.Biol., 21, 2014
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4CXJ
 | | BTB domain of KEAP1 C151W mutant | | 分子名称: | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 | | 著者 | Cleasby, A, Yon, J, Day, P.J, Richardson, C, Tickle, I.J, Williams, P.A, Callahan, J.F, Carr, R, Concha, N, Kerns, J.K, Qi, H, Sweitzer, T, Ward, P, Davies, T.G. | | 登録日 | 2014-04-07 | | 公開日 | 2014-06-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo.
Plos One, 9, 2014
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