2XSQ

Crystal structure of human Nudix motif 16 (NUDT16) in complex with IMP and magnesium

Summary for 2XSQ

Entry DOI	10.2210/pdb2xsq/pdb
Descriptor	U8 SNORNA-DECAPPING ENZYME, INOSINIC ACID, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase, mrna decapping, mrna turnover, structural genomics consortium, sgc
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus : Q96DE0
Total number of polymer chains	1
Total formula weight	24321.45
Authors	Tresaugues, L.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kol, S.,Kotenyova, T.,Kouznetsova, E.,Moche, M.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,van den Berg, S.,Wahlberg, E.,Weigelt, J.,Nordlund, P. (deposition date: 2010-09-29, release date: 2010-11-17, Last modification date: 2023-12-20)
Primary citation	Tresaugues, L.,Lundback, T.,Welin, M.,Flodin, S.,Nyman, T.,Silvander, C.,Graslund, S.,Nordlund, P. Structural Basis for the Specificity of Human Nudt16 and its Regulation by Inosine Monophosphate. Plos One, 10:31507-, 2015 Cited by PubMed: 26121039 DOI: 10.1371/JOURNAL.PONE.0131507 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation