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PDB: 17801 件

3CR8
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Hexameric APS kinase from Thiobacillus denitrificans
分子名称: Sulfate adenylyltransferase, adenylylsulfate kinase
著者Gay, S.C, Segel, I.H, Fisher, A.J.
登録日2008-04-04
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of the two-domain hexameric APS kinase from Thiobacillus denitrificans: structural basis for the absence of ATP sulfurylase activity.
Acta Crystallogr.,Sect.D, 65, 2009
3CVW
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Drosophila melanogaster (6-4) photolyase H365N mutant bound to ds DNA with a T-T (6-4) photolesion and cofactor F0
分子名称: 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2009-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and mechanism of a cofactor f0 accelerated (6-4) photolyase from the fruit fly
To be Published
2YC0
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH R-2-HYDROXYGLUTARATE
分子名称: (2R)-2-hydroxypentanedioic acid, FE (II) ION, GLYCEROL, ...
著者Chowdhury, R, Clifton, I.J, Schofield, C.J.
登録日2011-03-10
公開日2011-03-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
EMBO Rep., 12, 2011
5YP3
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Crystal structure of dipeptidyl peptidase IV (DPP IV) with Ile-Pro from Pseudoxanthomonas mexicana
分子名称: Dipeptidyl aminopeptidase 4, GLYCEROL, ISOLEUCINE, ...
著者Roppongi, S, Suzuki, Y, Tateoka, C, Fuimoto, M, Morisawa, S, Iizuka, I, Nakamura, A, Honma, N, Shida, Y, Ogasawara, W, Tanaka, N, Sakamoto, Y, Nonaka, T.
登録日2017-11-01
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues.
Sci Rep, 8, 2018
4R5G
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Crystal structure of the DnaK C-terminus with the inhibitor PET-16
分子名称: Chaperone protein DnaK, triphenyl(phenylethynyl)phosphonium
著者Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L.
登録日2014-08-21
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4501 Å)
主引用文献Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket.
Acs Chem.Biol., 9, 2014
2Y6A
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Ascorbate Peroxidase R38A mutant
分子名称: ASCORBATE PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Metcalfe, C.L, Efimov, I, Gumiero, A, Raven, E.L, Moody, P.C.E.
登録日2011-01-20
公開日2011-10-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Proton Delivery to Ferryl Heme in a Heme Peroxidase: Enzymatic Use of the Grotthuss Mechanism.
J.Am.Chem.Soc., 133, 2011
3GD3
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Crystal structure of a naturally folded murine apoptosis inducing factor
分子名称: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE
著者Sevrioukova, I.F.
登録日2009-02-23
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Redox-linked conformational dynamics in apoptosis-inducing factor
J.Mol.Biol., 390, 2009
2HMP
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Uncomplexed actin cleaved with protease ECP32
分子名称: 1,2-ETHANEDIOL, 2,2',2''-NITRILOTRIETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Klenchin, V.A, Khaitlina, S.Y, Rayment, I.
登録日2006-07-11
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Crystal structure of polymerization-competent actin
J.Mol.Biol., 362, 2006
4R0W
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Vvtgvta, an amyloid forming segment from alpha synuclein, residues 70-76
分子名称: Alpha-synuclein
著者Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R.
登録日2014-08-01
公開日2014-12-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4RGT
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2.0 Angstrom Crystal Structure of Superantigen-like Protein from Staphylococcus aureus in Complex with 3-N-Acetylneuraminyl-N-acetyllactosamine.
分子名称: DI(HYDROXYETHYL)ETHER, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein
著者Minasov, G, Nocadello, S, Shuvalova, L, Filippova, E.V, Halavaty, A, Dubrovska, I, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-09-30
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献2.0 Angstrom Crystal Structure of Superantigen-like Protein from Staphylococcus aureus in Complex with 3-N-Acetylneuraminyl-N-acetyllactosamine.
TO BE PUBLISHED
3P66
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BU of 3p66 by Molmil
Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme
分子名称: GOLD 3+ ION, Lysozyme C
著者Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y.
登録日2010-10-11
公開日2011-02-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.
Nat Nanotechnol, 6, 2011
2YDE
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH S-2-HYDROXYGLUTARATE
分子名称: (2S)-2-HYDROXYPENTANEDIOIC ACID, FE (III) ION, GLYCEROL, ...
著者Chowdhury, R, Clifton, I.J, Schofield, C.J.
登録日2011-03-18
公開日2011-03-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
EMBO Rep., 12, 2011
6K1G
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Crystal structure of the L-fucose isomerase soaked with Mn2+ from Raoultella sp.
分子名称: L-fucose isomerase, MANGANESE (II) ION
著者Kim, I.J, Kim, D.H, Nam, K.H, Kim, K.H.
登録日2019-05-10
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Enzymatic synthesis of l-fucose from l-fuculose using a fucose isomerase fromRaoultellasp. and the biochemical and structural analyses of the enzyme.
Biotechnol Biofuels, 12, 2019
7LOP
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BU of 7lop by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV05-163 and CR3022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2021-02-10
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.246 Å)
主引用文献Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.
Science, 373, 2021
1TKK
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The Structure of a Substrate-Liganded Complex of the L-Ala-D/L-Glu Epimerase from Bacillus subtilis
分子名称: ALANINE, GLUTAMIC ACID, MAGNESIUM ION, ...
著者Klenchin, V.A, Schmidt, D.M, Gerlt, J.A, Rayment, I.
登録日2004-06-08
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Evolution of Enzymatic Activities in the Enolase Superfamily: Structure of a Substrate-Liganded Complex of the l-Ala-d/l-Glu Epimerase from Bacillus subtilis(,).
Biochemistry, 43, 2004
3CVX
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Drosophila melanogaster (6-4) photolyase H369M mutant bound to ds DNA with a T-T (6-4) photolesion
分子名称: DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2009-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and mechanism of a coenzyme F0 accelerated (6-4) photolyase from the fruit fly
To be Published
3CN4
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Human transthyretin (TTR) in complex with N-(3,5-Dibromo-4-hydroxyphenyl)benzamide
分子名称: N-(3,5-dibromo-4-hydroxyphenyl)benzamide, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2008-03-24
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
2LO8
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Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA
分子名称: DNA_(5'-D(*GP*CP*CP*GP*CP*AP*GP*TP*GP*C)-3')_
著者Morrow, J.R, Fountain, M.A, del Mundo, I.A, Siter, K.E.
登録日2012-01-18
公開日2012-03-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA.
Inorg.Chem., 51, 2012
3G51
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Structural diversity of the active conformation of the N-terminal kinase domain of p90 ribosomal S6 kinase 2
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-3
著者Kurinov, I.
登録日2009-02-04
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2
Plos One, 4, 2009
2HG5
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Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter
分子名称: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, CESIUM ION, FAB HEAVY CHAIN, ...
著者Valiyaveetil, F.I, MacKinnon, R, Muir, T.W.
登録日2006-06-26
公開日2006-09-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
J.Am.Chem.Soc., 128, 2006
4RGZ
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Crystal structure of recombinant prolidase from Thermococcus sibiricus at P21221 spacegroup
分子名称: PHOSPHATE ION, Xaa-Pro aminopeptidase, ZINC ION
著者Timofeev, V.I, Korgenevsky, D.A, Gorbacheva, M.A, Boyko, K.M, Slutsky, E, Rakitina, T.V, Lipkin, A.V, Popov, V.O.
登録日2014-10-01
公開日2015-08-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of recombinant prolidase from Thermococcus sibiricus in space group P21221.
Acta Crystallogr.,Sect.F, 71, 2015
2LO5
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Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA, Structure of a Thymine bulge
分子名称: DNA (5'-D(*GP*GP*CP*CP*GP*CP*AP*GP*TP*GP*CP*C)-3')
著者Morrow, J.R, Fountain, M.A, del Mundo, I.A, Siter, K.E.
登録日2012-01-17
公開日2012-03-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA.
Inorg.Chem., 51, 2012
8UYS
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SARS-CoV-2 5' proximal stem-loop 5
分子名称: SARS-CoV-2 RNA SL5 domain.
著者Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R.
登録日2023-11-14
公開日2023-12-06
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
3CZL
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Crystal Structure Analysis of Sucrose hydrolase(SUH) E322Q-glucose complex
分子名称: alpha-D-glucopyranose, sucrose hydrolase
著者Kim, M.I, Rhee, S.
登録日2008-04-29
公開日2008-07-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures and mutagenesis of sucrose hydrolase from Xanthomonas axonopodis pv. glycines: insight into the exclusively hydrolytic amylosucrase fold.
J.Mol.Biol., 380, 2008
8UYJ
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BtCoV-HKU5 5' proximal stem-loop 5, conformation 4
分子名称: BtCoV-HKU5 5' proximal stem-loop 5, conformation 4
著者Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R.
登録日2023-11-13
公開日2023-12-06
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024

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件を2024-08-07に公開中

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