4H5J
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8CUK
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8DIT
| Cryo-EM structure of a HOPS core complex containing Vps33, Vps16, and Vps18 | Descriptor: | Vacuolar protein sorting-associated protein 16, Vacuolar protein sorting-associated protein 18, Vacuolar protein sorting-associated protein 33 | Authors: | Port, S.A, Farrell, P.D, Jeffrey, P.D, DiMaio, F, Hughson, F.M. | Deposit date: | 2022-06-29 | Release date: | 2022-08-31 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Cryo-EM structure of the HOPS core complex and its implication for SNARE assembly To Be Published
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6U3W
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1ZHH
| Crystal Structure of the Apo Form of Vibrio Harveyi LUXP Complexed with the Periplasmic Domain of LUXQ | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Autoinducer 2 sensor kinase/phosphatase luxQ, Autoinducer 2-binding periplasmic protein luxP | Authors: | Neiditch, M.B, Federle, M.J, Miller, S.T, Bassler, B.L, Hughson, F.M. | Deposit date: | 2005-04-25 | Release date: | 2005-05-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Regulation of LuxPQ Receptor Activity by the Quorum-Sensing Signal Autoinducer-2. Mol.Cell, 18, 2005
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4U6U
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1OT8
| Structure of the Ankyrin Domain of the Drosophila Notch Receptor | Descriptor: | MAGNESIUM ION, Neurogenic locus Notch protein | Authors: | Zweifel, M.E, Leahy, D.J, Hughson, F.M, Barrick, D. | Deposit date: | 2003-03-21 | Release date: | 2003-10-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and stability of the ankyrin domain of the Drosophila Notch receptor Protein Sci., 12, 2003
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8FTU
| Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1 | Authors: | Travis, S.M, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2023-01-13 | Release date: | 2023-03-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (5.73 Å) | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs. Nat.Struct.Mol.Biol., 31, 2024
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1JX6
| CRYSTAL STRUCTURE OF LUXP FROM VIBRIO HARVEYI COMPLEXED WITH AUTOINDUCER-2 | Descriptor: | 3A-METHYL-5,6-DIHYDRO-FURO[2,3-D][1,3,2]DIOXABOROLE-2,2,6,6A-TETRAOL, CALCIUM ION, LUXP PROTEIN | Authors: | Chen, X, Schauder, S, Potier, N, Van Dorsselaer, A, Pelczer, I, BassleR, B.L, Hughson, F.M. | Deposit date: | 2001-09-05 | Release date: | 2002-02-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural identification of a bacterial quorum-sensing signal containing boron. Nature, 415, 2002
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5EP0
| Quorum-Sensing Signal Integrator LuxO - Receiver+Catalytic Domains | Descriptor: | 1,2-ETHANEDIOL, Putative repressor protein luxO, SULFATE ION | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
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5EP2
| Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor | Descriptor: | 2,2-dimethylpropyl 2-[[3,5-bis(oxidanylidene)-2~{H}-1,2,4-triazin-6-yl]sulfanyl]ethanoate, ACETATE ION, Putative repressor protein luxO | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.421 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
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8EKI
| CryoEM structure of the Dsl1 complex bound to SNAREs Sec20 and Use1 | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC20, Protein transport protein SEC39, ... | Authors: | DAmico, K.A, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs. Nat.Struct.Mol.Biol., 31, 2024
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5BV0
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5BUZ
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5BV1
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1TM2
| Crystal Structure of the apo form of the Salmonella typhimurium AI-2 receptor LsrB | Descriptor: | sugar transport protein | Authors: | Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M. | Deposit date: | 2004-06-10 | Release date: | 2004-09-28 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2 Mol.Cell, 15, 2004
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1TJY
| Crystal Structure of Salmonella typhimurium AI-2 receptor LsrB in complex with R-THMF | Descriptor: | (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran, sugar transport protein | Authors: | Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M. | Deposit date: | 2004-06-07 | Release date: | 2004-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2 Mol.Cell, 15, 2004
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1HTM
| STRUCTURE OF INFLUENZA HAEMAGGLUTININ AT THE PH OF MEMBRANE FUSION | Descriptor: | HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN | Authors: | Bullough, P.A, Hughson, F.M, Skehel, J.J, Wiley, D.C. | Deposit date: | 1994-11-02 | Release date: | 1995-02-14 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of influenza haemagglutinin at the pH of membrane fusion. Nature, 371, 1994
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6U3V
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6TZT
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6XMD
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6XJL
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6XM1
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6WC3
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3ETU
| Crystal structure of yeast Dsl1p | Descriptor: | Protein transport protein DSL1 | Authors: | Ren, Y, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2008-10-08 | Release date: | 2009-01-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nat.Struct.Mol.Biol., 16, 2009
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