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PDB: 292 件
4YA1
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BU of 4ya1 by Molmil
Yeast 20S proteasome beta2-H116N mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Groll, M.
登録日2015-02-17
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y9Y
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BU of 4y9y by Molmil
Yeast 20S proteasome beta2-H116E mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Proteasome subunit alpha type-1, ...
著者Huber, E.M, Groll, M.
登録日2015-02-17
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4YA0
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BU of 4ya0 by Molmil
Yeast 20S proteasome beta2-H116E mutant in complex with Ac-PAE-ep
分子名称: Ac-PAE-ep, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-02-17
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8T
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BU of 4y8t by Molmil
Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAE-ep
分子名称: Ac-PAE-ep, MAGNESIUM ION, Proteasome subunit alpha type-1, ...
著者Huber, E.M, Groll, M.
登録日2015-02-16
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Z1L
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BU of 4z1l by Molmil
Yeast 20S proteasome in complex with belactosin C derivative 3
分子名称: (2S,3S)-2-{(1R)-2-[(3,5-dimethoxybenzyl)amino]-1-hydroxy-2-oxoethyl}-3-methylpentanoic acid, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-03-27
公開日2015-05-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Minimal beta-Lactone Fragment for Selective beta 5c or beta 5i Proteasome Inhibitors.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y8R
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BU of 4y8r by Molmil
Yeast 20S proteasome beta2-H116D mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-02-16
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y6A
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BU of 4y6a by Molmil
Yeast 20S proteasome beta2-H114D mutant in complex with Ac-PAD-ep
分子名称: Ac-PAD-ep, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-02-12
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
6HFM
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BU of 6hfm by Molmil
Hsp90 co-chaperone Cns1 C-domain from Saccharomyces cerevisiae
分子名称: Hsp70/Hsp90 co-chaperone CNS1, MAGNESIUM ION
著者Huber, E.M, Groll, M.
登録日2018-08-21
公開日2019-03-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
Mol.Cell, 74, 2019
5LX0
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BU of 5lx0 by Molmil
Cys-Gly dipeptidase GliJ (space group P3221)
分子名称: Dipeptidase, FE (III) ION
著者Huber, E.M, Groll, M.
登録日2016-09-19
公開日2017-05-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ.
ACS Chem. Biol., 12, 2017
6HFO
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BU of 6hfo by Molmil
Human Hsp90 co-chaperone TTC4 C-domain
分子名称: PHOSPHATE ION, Tetratricopeptide repeat protein 4
著者Huber, E.M, Groll, M.
登録日2018-08-21
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
Mol.Cell, 74, 2019
6HFT
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BU of 6hft by Molmil
Hsp90 co-chaperone Cns1 from Saccharomyces cerevisiae (delta69)
分子名称: Hsp70/Hsp90 co-chaperone CNS1, MAGNESIUM ION
著者Huber, E.M, Groll, M.
登録日2018-08-21
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
Mol.Cell, 74, 2019
4QUY
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BU of 4quy by Molmil
yCP beta5-A49S-mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-14
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QW3
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BU of 4qw3 by Molmil
yCP beta5-C63F mutant in complex with bortezomib
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-16
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QZ3
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BU of 4qz3 by Molmil
yCP beta5-A49V mutant in complex with the epoxyketone inhibitor ONX 0914
分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-27
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QZ4
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BU of 4qz4 by Molmil
yCP beta5-A49S mutant in complex with the epoxyketone inhibitor ONX 0914
分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-27
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVQ
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BU of 4qvq by Molmil
yCP beta5-M45I mutant in complex with bortezomib
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-15
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QWI
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BU of 4qwi by Molmil
yCP beta5-A49S-mutant in complex with carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-16
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV7
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BU of 4qv7 by Molmil
yCP beta5-A50V mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-14
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QW0
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BU of 4qw0 by Molmil
yCP beta5-A49T-A50V-double mutant in complex with bortezomib
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-16
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV5
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BU of 4qv5 by Molmil
yCP beta5-M45I mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-14
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QZ5
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BU of 4qz5 by Molmil
yCP beta5-A49T-mutant in complex with ONX 0914
分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-27
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QWG
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BU of 4qwg by Molmil
yCP beta5-A49V mutant in complex with carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-16
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV9
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BU of 4qv9 by Molmil
yCP beta5-C63F mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-14
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QW4
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BU of 4qw4 by Molmil
yCP in complex with carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-16
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QWU
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BU of 4qwu by Molmil
yCP beta5-C52F mutant in complex with bortezomib
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-17
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015

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