6TQN
| rrn anti-termination complex without S4 | 分子名称: | 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | 登録日 | 2019-12-17 | 公開日 | 2020-08-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6TQO
| rrn anti-termination complex | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | 登録日 | 2019-12-17 | 公開日 | 2020-08-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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7RMR
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7RMQ
| Crystal structure of cycloviolacin O2 | 分子名称: | Cycloviolacin O2, D-[I11L]cycloviolacin O2, FORMIC ACID | 著者 | Huang, Y.H, Du, Q. | 登録日 | 2021-07-28 | 公開日 | 2021-09-22 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides. Molecules, 26, 2021
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7RMS
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7YM1
| Structure of SsbA protein in complex with the anticancer drug 5-fluorouracil | 分子名称: | 5-FLUOROURACIL, GLYCEROL, Single-stranded DNA-binding protein | 著者 | Huang, Y.H, Yang, P.C, Chiang, W.Y, Lin, E.S, Huang, C.Y. | 登録日 | 2022-07-27 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Crystal Structure of DNA Replication Protein SsbA Complexed with the Anticancer Drug 5-Fluorouracil. Int J Mol Sci, 24, 2023
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8WQ9
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4QXW
| Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | 著者 | Huang, Y.H, Gandhi, A.K, Russell, A, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2014-07-22 | 公開日 | 2014-11-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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5YKD
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5DZL
| Crystal structure of the protein human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1 | 著者 | Huang, Y.H, Russell, A, Gandhi, A.K, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2015-09-25 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4006 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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4F5E
| Crystal structure of ERIS/STING | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Transmembrane protein 173 | 著者 | Huang, Y.H, Liu, X.Y, Su, X.D. | 登録日 | 2012-05-13 | 公開日 | 2012-06-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | The structural basis for the sensing and binding of cyclic di-GMP by STING Nat.Struct.Mol.Biol., 19, 2012
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4F5D
| ERIS/STING in complex with ligand | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Transmembrane protein 173 | 著者 | Huang, Y.H, Liu, X.Y, Su, X.D. | 登録日 | 2012-05-13 | 公開日 | 2012-06-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structural basis for the sensing and binding of cyclic di-GMP by STING Nat.Struct.Mol.Biol., 19, 2012
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5YNZ
| Crystal structure of the dihydroorotase domain (K1556A) of human CAD | 分子名称: | CAD protein, ZINC ION | 著者 | Huang, Y.H, Chen, K.L, Cheng, J.H, Huang, C.Y. | 登録日 | 2017-10-26 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.774 Å) | 主引用文献 | Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site Biochem. Biophys. Res. Commun., 505, 2018
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5YUO
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6AEQ
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5YYU
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6AEP
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5XGT
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6AJD
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6JDG
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6IRQ
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6KLK
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5YUN
| Crystal structure of SSB complexed with myc | 分子名称: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein | 著者 | Huang, Y.H, Huang, C.Y. | 登録日 | 2017-11-22 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal structure of SSB complexed with inhibitor myricetin. Biochem. Biophys. Res. Commun., 504, 2018
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6IB7
| Structure of wild type SuhB | 分子名称: | GLYCEROL, Inositol-1-monophosphatase, MAGNESIUM ION | 著者 | Huang, Y.H, Loll, B, Wahl, M.C. | 登録日 | 2018-11-29 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis. Nucleic Acids Res., 47, 2019
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6IB8
| Structure of a complex of SuhB and NusA AR2 domain | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, Inositol-1-monophosphatase, ... | 著者 | Huang, Y.H, Loll, B, Wahl, M.C. | 登録日 | 2018-11-29 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.646 Å) | 主引用文献 | Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis. Nucleic Acids Res., 47, 2019
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