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PDB: 66 件

6TQN
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rrn anti-termination complex without S4
分子名称: 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N.
登録日2019-12-17
公開日2020-08-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis.
Mol.Cell, 79, 2020
6TQO
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rrn anti-termination complex
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ...
著者Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N.
登録日2019-12-17
公開日2020-08-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis.
Mol.Cell, 79, 2020
7RMR
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Crystal structure of [I11L]cycloviolacin O2
分子名称: D-[I11L]cycloviolacin O2, THIOCYANATE ION, [I11L]cycloviolacin O2
著者Huang, Y.H, Du, Q, Craik, D.J.
登録日2021-07-28
公開日2021-09-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides.
Molecules, 26, 2021
7RMQ
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Crystal structure of cycloviolacin O2
分子名称: Cycloviolacin O2, D-[I11L]cycloviolacin O2, FORMIC ACID
著者Huang, Y.H, Du, Q.
登録日2021-07-28
公開日2021-09-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides.
Molecules, 26, 2021
7RMS
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Crystal structure of [I11G]cycloviolacin O2
分子名称: D-[I11L]cycloviolacin O2, THIOCYANATE ION, [I11L]cycloviolacin O2
著者Huang, Y.H, Du, Q, Craik, D.J.
登録日2021-07-28
公開日2021-09-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides.
Molecules, 26, 2021
7YM1
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Structure of SsbA protein in complex with the anticancer drug 5-fluorouracil
分子名称: 5-FLUOROURACIL, GLYCEROL, Single-stranded DNA-binding protein
著者Huang, Y.H, Yang, P.C, Chiang, W.Y, Lin, E.S, Huang, C.Y.
登録日2022-07-27
公開日2023-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Crystal Structure of DNA Replication Protein SsbA Complexed with the Anticancer Drug 5-Fluorouracil.
Int J Mol Sci, 24, 2023
8WQ9
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BU of 8wq9 by Molmil
Crystal structure of dihydropyrimidinase complexed with gamma-aminobutyric acid
分子名称: D-hydantoinase/dihydropyrimidinase, GAMMA-AMINO-BUTANOIC ACID, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2023-10-11
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The complexed crystal structure of dihydropyrimidinase reveals a potential interactive link with the neurotransmitter gamma-aminobutyric acid (GABA).
Biochem.Biophys.Res.Commun., 692, 2024
4QXW
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Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain
分子名称: Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside
著者Huang, Y.H, Gandhi, A.K, Russell, A, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S.
登録日2014-07-22
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Nature, 517, 2015
5YKD
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Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 at 2.17 angstrom resolution
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2017-10-14
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis for pH-Dependent Oligomerization of Dihydropyrimidinase fromPseudomonas aeruginosaPAO1.
Bioinorg Chem Appl, 2018, 2018
5DZL
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Crystal structure of the protein human CEACAM1
分子名称: Carcinoembryonic antigen-related cell adhesion molecule 1
著者Huang, Y.H, Russell, A, Gandhi, A.K, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S.
登録日2015-09-25
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4006 Å)
主引用文献CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Nature, 517, 2015
4F5E
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Crystal structure of ERIS/STING
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Transmembrane protein 173
著者Huang, Y.H, Liu, X.Y, Su, X.D.
登録日2012-05-13
公開日2012-06-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献The structural basis for the sensing and binding of cyclic di-GMP by STING
Nat.Struct.Mol.Biol., 19, 2012
4F5D
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ERIS/STING in complex with ligand
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Transmembrane protein 173
著者Huang, Y.H, Liu, X.Y, Su, X.D.
登録日2012-05-13
公開日2012-06-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structural basis for the sensing and binding of cyclic di-GMP by STING
Nat.Struct.Mol.Biol., 19, 2012
5YNZ
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BU of 5ynz by Molmil
Crystal structure of the dihydroorotase domain (K1556A) of human CAD
分子名称: CAD protein, ZINC ION
著者Huang, Y.H, Chen, K.L, Cheng, J.H, Huang, C.Y.
登録日2017-10-26
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.774 Å)
主引用文献Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site
Biochem. Biophys. Res. Commun., 505, 2018
5YUO
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BU of 5yuo by Molmil
Crystal structure of SSB protein from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, Single-stranded DNA-binding protein
著者Huang, Y.H, Huang, C.Y.
登録日2017-11-22
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.037 Å)
主引用文献The glycine-rich flexible region in SSB is crucial for PriA stimulation.
RSC Adv., 8, 2018
6AEQ
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BU of 6aeq by Molmil
Crystal structure of the ssDNA-binding domain of DnaT from Salmonella enterica Serovar Typhimurium LT2
分子名称: Primosomal protein 1
著者Huang, Y.H, Huang, C.Y.
登録日2018-08-06
公開日2019-03-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2518084 Å)
主引用文献Crystal structure of the C-terminal domain of the primosomal DnaT protein: Insights into a new oligomerization mechanism.
Biochem. Biophys. Res. Commun., 511, 2019
5YYU
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BU of 5yyu by Molmil
Crystal structure of Staphylococcus aureus single-stranded DNA-binding protein SsbB
分子名称: Single-stranded DNA-binding protein
著者Huang, Y.H, Huang, C.Y.
登録日2017-12-11
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献Characterization of single-stranded DNA-binding protein SsbB from Staphylococcus aureus: SsbB cannot stimulate PriA helicase.
Rsc Adv, 8, 2018
6AEP
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Crystal structure of the ssDNA-binding domain of DnaT from Salmonella enterica Serovar Typhimurium LT2 at 1.84 angstrom resolution
分子名称: Primosomal protein 1
著者Huang, Y.H, Huang, C.Y.
登録日2018-08-06
公開日2019-08-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.844 Å)
主引用文献Crystal structure of the ssDNA-binding domain of DnaT from Salmonella enterica Serovar Typhimurium LT2 at 1.84 angstrom resolution
To Be Published
5XGT
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BU of 5xgt by Molmil
Crystal structure of the N-terminal domain of Staphylococcus aureus single-stranded DNA-binding protein SsbA at 1.82 angstrom resolution
分子名称: GLYCEROL, Single-stranded DNA-binding protein
著者Huang, Y.H, Chen, C.J, Huang, C.Y.
登録日2017-04-17
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Staphylococcus aureus single-stranded DNA-binding protein SsbA can bind but cannot stimulate PriA helicase.
PLoS ONE, 12, 2017
6AJD
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BU of 6ajd by Molmil
Crystal structure of a monometallic dihydropyrimidinase from Pseudomonas aeruginosa PAO1 reveals no lysine carbamylation within the active site
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2018-08-27
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.223 Å)
主引用文献Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site
Biochem. Biophys. Res. Commun., 505, 2018
6JDG
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Complexed crystal structure of PaSSB with ssDNA dT20 at 2.39 angstrom resolution
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Single-stranded DNA-binding protein
著者Huang, Y.H, Huang, C.Y.
登録日2019-02-01
公開日2019-12-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.388 Å)
主引用文献Complexed crystal structure of SSB reveals a novel single-stranded DNA binding mode (SSB)3:1: Phe60 is not crucial for defining binding paths.
Biochem.Biophys.Res.Commun., 520, 2019
6IRQ
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BU of 6irq by Molmil
Complexed crystal structure of PaSSB with ssDNA dT25 at 1.91 angstrom resolution
分子名称: DNA (25-MER), Single-stranded DNA-binding protein
著者Huang, Y.H, Huang, C.Y.
登録日2018-11-14
公開日2019-12-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Characterization of an SSB-dT25 complex: structural insights into the S-shaped ssDNA binding conformation.
Rsc Adv, 9, 2019
6KLK
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Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU
分子名称: 5-FLUOROURACIL, D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Chen, I.C, Huang, C.Y.
登録日2019-07-30
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.759 Å)
主引用文献Crystal structure of dihydropyrimidinase in complex with anticancer drug 5-fluorouracil.
Biochem.Biophys.Res.Commun., 519, 2019
5YUN
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Crystal structure of SSB complexed with myc
分子名称: 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein
著者Huang, Y.H, Huang, C.Y.
登録日2017-11-22
公開日2018-10-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structure of SSB complexed with inhibitor myricetin.
Biochem. Biophys. Res. Commun., 504, 2018
6IB7
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Structure of wild type SuhB
分子名称: GLYCEROL, Inositol-1-monophosphatase, MAGNESIUM ION
著者Huang, Y.H, Loll, B, Wahl, M.C.
登録日2018-11-29
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.245 Å)
主引用文献Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis.
Nucleic Acids Res., 47, 2019
6IB8
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Structure of a complex of SuhB and NusA AR2 domain
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, Inositol-1-monophosphatase, ...
著者Huang, Y.H, Loll, B, Wahl, M.C.
登録日2018-11-29
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.646 Å)
主引用文献Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis.
Nucleic Acids Res., 47, 2019

 

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